Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Steven Messina-Graham"'
Publikováno v:
Blood Cells, Molecules, and Diseases. 58:13-18
SDF-1/CXCL12 is a potent chemokine required for the homing and engraftment of hematopoietic stem and progenitor cells. Previous Data from our group has shown that in an SDF-1/CXCL12 transgenic mouse model, Lineage− Sca-1+ c-Kit+ (LSK) bone marrow c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899d8f2bbb2a2a32af53d65d89e1a912
https://doi.org/10.1016/j.bcmd.2016.01.008
https://doi.org/10.1016/j.bcmd.2016.01.008
Publikováno v:
STEM CELLS. 32:1183-1194
SIRT1, an NAD-dependent deacetylase, plays a role in regulation of autophagy. SIRT1 increases mitochondrial function and reduces oxidative stress, and has been linked to age-related reactive oxygen species (ROS) generation, which is highly dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cebc8900537436d157934111982f44
https://doi.org/10.1002/stem.1641
https://doi.org/10.1002/stem.1641
Autor:
Hal E. Broxmeyer, Nieves Velez de Mendizabal, Robert Matthew Strother, Robert R. Bies, Sherif S. Farag, Steven Messina-Graham, Shripad D. Chitnis
Publikováno v:
Clinical Pharmacokinetics. 53:247-259
Background and Objectives Dipeptidyl peptidase-4 (DPP4) inhibition is a potential strategy to increase the engraftment rate of haematopoietic stem/progenitor cells. A recent clinical trial using sitagliptin, a DPP4 inhibitor approved for type 2 diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::487867743d6196e28cf94b8a95e64216
https://doi.org/10.1007/s40262-013-0109-y
https://doi.org/10.1007/s40262-013-0109-y
Publikováno v:
Cryobiology. 85:157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0b1eddddc5190d47515860b32b51d1
https://doi.org/10.1016/j.cryobiol.2018.10.146
https://doi.org/10.1016/j.cryobiol.2018.10.146
Autor:
Angie Secrest, Rafat Abonour, Michael J. Robertson, Kenneth Cornetta, R. Matthew Strother, Steven Messina-Graham, Jennifer E. Schwartz, David R. Jones, Lisa L. Wood, Shivani Srivastava, Hal E. Broxmeyer, Sherif S. Farag
Publikováno v:
Stem Cells and Development. 22:1007-1015
Delayed engraftment is a significant limitation of umbilical cord blood (UCB) transplantation due to low stem cell numbers. Inhibition of dipeptidyl peptidase (DPP)-4 enhanced engraftment in murine transplants. We evaluated the feasibility of systemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982ef8bb2fc865d4875ad5f8cdfbe9fb
https://doi.org/10.1089/scd.2012.0636
https://doi.org/10.1089/scd.2012.0636
Autor:
Jonathan Hoggatt, Giao Hangoc, Steven Messina-Graham, Sara L. Rohrabaugh, Sherif S. Farag, Brahmananda R. Chitteti, Louis M. Pelus, Heather O'Leary, Xuan Ou, Jennifer M. Speth, Hal E. Broxmeyer, Timothy B. Campbell, Scott Cooper, Charlie Mantel, Edward F. Srour
Publikováno v:
Nature Medicine. 18:1786-1796
Enhancement of hematopoietic recovery after radiation, chemotherapy, or hematopoietic stem cell (HSC) transplantation is clinically relevant. Dipeptidylpeptidase (DPP4) cleaves a wide variety of substrates, including the chemokine stromal cell-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5807d47d67c4562960e4f6254fe24379
https://doi.org/10.1038/nm.2991
https://doi.org/10.1038/nm.2991
Autor:
Xin-Yuan Fu, Steven Messina-Graham, Hal E. Broxmeyer, Giao Hangoc, Akira Moh, Scott Cooper, Charlie Mantel
Publikováno v:
Blood. 120:2589-2599
Nuclear transcription factor Stat3 is important for proper regulation of hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) proliferation, survival, and cytokine signaling responses. A new, noncanonical role for Stat3 in mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769551c9477d73d51f638b8b3b22374d
https://doi.org/10.1182/blood-2012-01-404004
https://doi.org/10.1182/blood-2012-01-404004
Autor:
Alice Y. Shih, Robert F. Mattrey, Warren C. Plaisted, Annelie E. Abrahamsson Schairer, Isabel G. Newton, Catriona Jamieson, Evan Y. Snyder, Steven Messina-Graham
Publikováno v:
Contrast Media & Molecular Imaging. 7:525-536
Capitalizing on cellular homing to cancer is a promising strategy for targeting malignant cells for diagnostic, monitoring and therapeutic purposes. Murine C17.2 neural progenitor cells (NPC) demonstrate a tropism for cell line-derived tumors, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daf6769ee5a3112a12a7f1d22258c0bf
https://doi.org/10.1002/cmmi.1485
https://doi.org/10.1002/cmmi.1485
Publikováno v:
Blood. 126:2389-2389
SDF-1, also known as CXCL12, is a potent and well-characterized chemokine required for the homing and engraftment of hematopoietic stem and progenitor cells (HSPCs) during hematopoietic stem cell transplantation (Sharma et al., 2011, Stem Cells Dev.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::199535dd9f3300f1db1c63331a18b470
https://doi.org/10.1182/blood.v126.23.2389.2389
https://doi.org/10.1182/blood.v126.23.2389.2389
Autor:
Mircea Ivan, Xinxin Huang, Reuben Kapur, Hal E. Broxmeyer, Kye Seong Kim, Louis M. Pelus, Giao Hangoc, Nadia Falah, Heather O'Leary, Scott Cooper, Nickolay Brustovetsky, Charlie Mantel, Steven Messina-Graham, Man Ryul Lee, Brahmananda R. Chitteti, Edward F. Srour
Publikováno v:
Blood. 124:2905-2905
Hematopoietic stem cells (HSCs) reside in hypoxic niches within the bone marrow (BM). Yet, all HSC studies have been performed to date with cells immediately isolated in non-physiologic ambient air, whether or not they are subsequently processed in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caa6e0cf27bb54d64724d72441047472
https://doi.org/10.1182/blood.v124.21.2905.2905
https://doi.org/10.1182/blood.v124.21.2905.2905