Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Steven McGraw"'
Autor:
Jonathan S. Bleeker, MD, Christopher J. Sumey, MD, Steven F. Powell, MD, Preston D. Steen, MD, Michael D. Keppen, MD, Michele Lohr, MD, Thavam Thambi-Pillai, MD, Peter Kurniali, MD, Miroslaw Mazurczak, MD, Mark M. Gitau, MD, Miran J. Blanchard, MD, Ryan K. Nowak, MD, Steven McGraw, MD, Robert Sticca, MD, Daniel Tuvin, MD, Gary Timmerman, MD
Publikováno v:
Surgery Open Science, Vol 2, Iss 4, Pp 25-31 (2020)
Background: Treatment paradigms for borderline resectable pancreatic cancer are evolving with increasing use of neoadjuvant chemotherapy and neoadjuvant chemoradiation. Variations in the definition of borderline resectable pancreatic cancer and neoad
Externí odkaz:
https://doaj.org/article/5d764d46775f4490a0e8ad7e217a1857
Autor:
Kathryn A. Gold, Ezra E.W. Cohen, Christopher D. Fischer, Christopher Joseph Sumey, Ryan Kenneth Nowak, Steven McGraw, Paul A. Thompson, William C. Spanos, Juan Luis Callejas-Valera, Ashley Wayne Jensen, Miran J. Blanchard, Michele Lohr, Lora Jane Black, Mark M. Gitau, Julie Bykowski, Steven Francis Powell, Christie Ellison, John H. Lee
Publikováno v:
J Clin Oncol
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 38, iss 21
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 38, iss 21
PURPOSE Pembrolizumab is a humanized monoclonal antibody that blocks interaction between programmed death receptor-1 (PD-1) and its ligands (PD-L1, PD-L2). Although pembrolizumab is approved for recurrent/metastatic head and neck squamous cell carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19be478bffc9e3635bed30f4041686a2
https://europepmc.org/articles/PMC7365766/
https://europepmc.org/articles/PMC7365766/
Autor:
Caterina Giannini, David Schiff, Timothy J. Kaufmann, S. Keith Anderson, Jann N. Sarkaria, Patrick J. Flynn, Evanthia Galanis, Patrick J. Peller, Paul D. Brown, Daniel J. Ma, Steven McGraw, Keith L. Ligon, Kurt A. Jaeckle, Joon H. Uhm, Jan C. Buckner
Publikováno v:
Neuro-Oncology. 17:1261-1269
Background The mammalian target of rapamycin (mTOR) functions within the phosphatidylinositol-3 kinase (PI3K)/Akt pathway as a critical modulator of cell survival. This clinical trial evaluated the combination of the mTOR inhibitor everolimus with co
Autor:
Sonja Althammer, Keith Steele, Marlon Rebelatto, Tze Heng Tan, Tobias Wiestler, Guenter Schmidt, Brandon Higgs, Xia Li, Li Shi, Xiaoping Jin, Joyce Antal, Ashok Gupta, Koustubh Ranade, Gerd Binning, Joaquim Bellmunt, Ronald de Wit, David J. Vaughn, Yves Fradet, Jae Lyun Lee, Lawrence Fong, Nicholas J. Vogelzang, Miguel A. Climent, Daniel P. Petrylak, Toni K. Choueiri, Andrea Necchi, Winald Gerritsen, Howard Gurney, David I. Quinn, Stéphane Culine, Cora N. Sternberg, Yabing Mai, Markus Puhlmann, Rodolfo F. Perini, Dean F. Bajorin, Padmanee Sharma, Margaret K. Callahan, Emiliano Calvo, Joseph W. Kim, Filipo de Braud, Patrick A. Ott, Petri Bono, Rathi N. Pillai, Michael Morse, Dung T. Le, Matthew Taylor, Pavlina Spilliopoulou, Johanna Bendell, Dirk Jaeger, Emily Chan, Scott J. Antonia, Paolo A. Ascierto, Delphine Hennicken, Marina Tschaika, Alex Azrilevich, Jonathan Rosenberg, Ofer Levy, Christopher Chan, Gady Cojocaru, Spencer Liang, Eran Ophir, Sudipto Ganguly, Amir Toporik, Maya Kotturi, Tal Fridman Kfir, Benjamin M. Murter, Kathryn Logronio, Liat Dassa, Ling Leung, Shirley Greenwald, Meir Azulay, Sandeep Kumar, Zoya Alteber, Xiaoyu Pan, Arthur Machlenkin, Yair Benita, Andrew W. Drake, Ayelet Chajut, Ran Salomon, Ilan Vankin, Einav Safyon, John Hunter, Zurit Levine, Mark White, Rom Leidner, Hyunseok Kang, Robert Haddad, Neil H. Segal, Lori J. Wirth, Robert L. Ferris, F. Stephen Hodi, Rachel E. Sanborn, Thomas F. Gajewski, William Sharfman, Dan McDonald, Shivani Srivastava, Xuemin Gu, Penny Phillips, Chaitali Passey, Tanguy Seiwert, Tsadik Habtetsion, Gang Zhou, Donastas Sakellariou-Thompson, Cara Haymaker, Caitlin Creasy, Mark Hurd, Naohiro Uraoka, Jaime Rodriguez Canales, Scott Koptez, Patrick Hwu, Anirban Maitra, Chantale Bernatchez, Scott M. Coyle, Kole T. Roybel, Levi J. Rupp, Stephen P. Santoro, Stephanie Secrest, Michael Spelman, Hanson Ho, Tina Gomes, Tiffany Tse, Chia Yung-Wu, Jack Taunton, Wendell Lim, Peter Emtage, Tarsem Moudgil, Carmen Ballesteros-Merino, Traci Hilton, Christopher Paustian, David Page, Walter Urba, Bernard Fox, Bryan Bell, Ashish Patel, Tove Olafsen, Daulet Satpayev, Michael Torgov, Filippo Marchioni, Jason Romero, Ziyue Karen Jiang, Charles Zamilpa, Jennifer S. Keppler, Alessandro Mascioni, Fang Jia, Chen-Yu Lee, Jean Gudas, Ryan J. Sullivan, Yujin Hoshida, Theodore Logan, Nikhil Khushalani, Anita Giobbie-Hurder, Kim Margolin, Joanna Roder, Rupal Bhatt, Henry Koon, Thomas Olencki, Thomas Hutson, Brendan Curti, Shauna Blackmon, James W. Mier, Igor Puzanov, Heinrich Roder, John Stewart, Asim Amin, Marc S. Ernstoff, Joseph I. Clark, Michael B. Atkins, Howard L. Kaufman, Jeffrey Sosman, Sabina Signoretti, David F. McDermott, Abraham A. Anderson, Mohammed M. Milhem, Robert H. I. Andtbacka, David Minor, Kevin S. Gorski, Daniel M. Baker, Omid Hamid, Emmanuel Akporiaye, Yoshinobu Koguchi, Kim Sutcliffe, Kristie Conder, Thomas Marron, Nina Bhardwaj, Linda Hammerich, Fiby George, Seunghee Kim-Schulze, Tibor Keler, Tom Davis, Elizabeth Crowley, Andres Salazar, Joshua Brody, Arta Monjazeb, Megan E. Daly, Jonathan Riess, Tianhong Li, William J. Murphy, Karen Kelly, Zhiwei Hu, Rulong Shen, Amanda Campbell, Elizabeth McMichael, Lianbo Yu, Bhuvaneswari Ramaswam, Cheryl A. London, Tian Xu, William Carson, Kathleen M. Kokolus, Elizabeth A. Repasky, Todd D. Schell, Joseph D. Drabick, David J. Messenheimer, Shawn Jensen, Mark Rubinstein, Kristina Andrijauskaite, Marzena Swiderska-syn, Kristin Lind, Agnes Choppin, Marina K. Roell, John Wrangle, Peter Rhode, Hing Wong, Shamim Ahmad, Mason Webb, Rasha Abu-Eid, Rajeev Shrimali, Vivek Verma, Atbin Doroodchi, Zuzana Berrong, David Yashar, Raed Samara, Mikayel Mkrtichyan, Samir Khleif, Steven Powell, Mark Gitau, Christopher Sumey, Andrew Terrell, Michele Lohr, Ryan K. Nowak, Steven McGraw, Ash Jensen, Miran Blanchard, Kathryn A. Gold, Ezra E. W. Cohen, Christie Ellison, Lora Black, John Lee, William Chad Spanos, Erik Wennerberg, Emily Schwitzer, Claire Lhuillier, Graeme Koelwyn, Rebecca Hiner, Lee Jones, Sandra Demaria, Vandeveer Amanda, John W. Greiner, Jeffrey Schlom, Michelle Bookstaver, Christopher M. Jewell, Andrew Gunderson, Brian Boulmay, Rui Li, Bradley Spieler, Kyle Happel, Zipei Feng, Christopher Dubay, Brenda Fisher, Sandra Aung, Eileen Mederos, Carlo B. Bifulco, Michael McNamara, Keith Bahjat, William Redmond, Augusto Ochoa, Hong-Ming Hu, Adi Mehta, Fridtjof Lund-Johansen, Frank Bedu-Addo, Greg Conn, Michael King, Panna Dutta, Robert Shepard, Mark Einstein, Sylvia Adams, Ena Wang, Ping Jin, Yelena Novik, Debra Morrison, Ruth Oratz, Franco M. Marincola, David Stroncek, Judith Goldberg, Silvia C. Formenti, Jérôme Galon, Bernhard Mlecnik, Florence Marliot, Fang-Shu Ou, Alessandro Lugli, Inti Zlobec, Tilman T. Rau, Iris D. Nagtegaal, Elisa Vink-Borger, Arndt Hartmann, Carol Geppert, Michael H. Roehrl, Prashant Bavi, Pamela S. Ohashi, Julia Y. Wang, Linh T. Nguyen, SeongJun Han, Heather L. MacGregor, Sara Hafezi-Bakhtiari, Bradley G. Wouters, Yutaka Kawakami, Boryana Papivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Kyogo Itoh, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Marc Van den Eynde, Anne Jouret-Mourin, Jean-Pascal Machiels, Tessa Fredriksen, Lucie Lafontaine, Bénédicte Buttard, Sarah Church, Pauline Maby, Helen Angell, Mihaela Angelova, Angela Vasaturo, Gabriela Bindea, Anne Berger, Christine Lagorce, Prabhu S. Patel, Hemangini H. Vora, Birva Shah, Jayendrakumar B. Patel, Kruti N. Rajvik, Shashank J. Pandya, Shilin N. Shukla, Yili Wang, Guanjun Zhang, Giuseppe V. Masucci, Emilia K. Andersson, Fabio Grizzi, Luigi Laghi, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Cilberto, Franco Marincola, Daniel J. Sargent, Bernard A. Fox, Alain Algazi, Katy Tsai, Michael Rosenblum, Prachi Nandoskar, Amy Li, John Nonomura, Kathryn Takamura, Mary Dwyer, Erica Browning, Reneta Talia, Chris Twitty, Sharron Gargosky, Jean Campbell, Mai Le, Robert H. Pierce, Adil Daud, Robyn Gartrell, Douglas Marks, Edward Stack, Yan Lu, Daisuke Izaki, Kristen Beck, Dan Tong Jia, Paul Armenta, Ashley White-Stern, Yichun Fu, Zoe Blake, Bret Taback, Basil Horst, Yvonne M. Saenger, Steven Leonardo, Keith Gorden, Ross B. Fulton, Kathryn Fraser, Takashi O. Kangas, Richard Walsh, Kathleen Ertelt, Jeremy Graff, Mark Uhlik, Jennifer S. Sims, Liang Lei, Takashi Tsujiuchi, Jeffrey N. Bruce, Peter Canoll, Anthony W Tolcher, Evan W Alley, Gurunadh Chichili, Jan E Canoll, Paul Moore, Ezio Bonvini, Syd Johnson, Sadhna Shankar, James Vasselli, Jon Wigginton, John Powderly
Publikováno v:
Journal for ImmunoTherapy of Cancer. 4
O1 Combinatorial CD8+ and PD-L1+ cell densities correlate with response and improved survival in non-small cell lung cancer (NSCLC) patients treated with durvalumab #### Sonja Althammer1, Keith Steele2, Marlon Rebelatto2, Tze Heng Tan1, Tobias Wiestl
Autor:
Wenting Wu, Joon H. Uhm, Caterina Giannini, Jann N. Sarkaria, Steven McGraw, Kurt A. Jaeckle, Patrick J. Peller, Evanthia Galanis, Paul D. Brown, Jan C. Buckner
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 81:468-475
Background The mammalian target of rapamycin (mTOR) functions within the PI3K/Akt signaling pathway as a critical modulator of cell survival. On the basis of promising preclinical data, the safety and tolerability of therapy with the mTOR inhibitor R
Autor:
Thavam C. Thambi-Pillai, Preston D. Steen, Peter Kurniali, Michael D. Keppen, Steven Francis Powell, Robert Sticca, Daniel Tuvin, Mark M. Gitau, Miran J. Blanchard, Jonathan Bleeker, Gary Timmerman, Christopher Joseph Sumey, Steven McGraw, Miroslaw Mazurczak, Michele Lohr, Ryan Kenneth Nowak
Publikováno v:
Journal of Clinical Oncology. 36:493-493
493 Background: Treatment paradigms for borderline resectable pancreatic cancer (BRPC) continue to evolve with increasing use of neoadjuvant chemotherapy (NAC) and chemoradiation (NACR). Variations in the definition of BRPC and in neoadjuvant approac
Autor:
Michele Lohr, Ezra E.W. Cohen, William C. Spanos, Andrew M Terrell, Lora Jane Black, Steven Francis Powell, Paul A. Thompson, Mark M. Gitau, Christopher Joseph Sumey, Steven McGraw, Ashley W. Jensen, Ryan Kenneth Nowak, Kathryn A. Gold, Miran J. Blanchard, John H. Lee, John Reynolds, Christie Ellison
Publikováno v:
Journal of Clinical Oncology. 35:6011-6011
6011 Background: Pembrolizumab (pembro) is a humanized monoclonal antibody that blocks the programmed death receptor-1 (PD-1) interaction with its ligands (PD-L1, PD-L2). While pembro is approved for platinum-refractory, recurrent/metastatic SCCHN, i
Autor:
Wenting Wu, Jann N. Sarkaria, Patrick J. Flynn, Caterina Giannini, Daniel J. Ma, David Schiff, Patrick J. Peller, Joon H. Uhm, Kurt A. Jaeckle, Evanthia Galanis, Steven McGraw, Jan C. Buckner, Paul D. Brown
Publikováno v:
Journal of Clinical Oncology. 30:2031-2031
2031 Background: The mammalian target of rapamycin (mTOR) functions within the PI3K/Akt pathway as a critical modulator of cell survival. Preclinical studies in GBM indicate that the combination of mTOR inhibitors, such as everolimus (RAD001), with e