Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Steven McClellan"'
Autor:
Rebecca M. Borneman, Elaine Gavin, Alla Musiyenko, Wito Richter, Kevin J. Lee, David K. Crossman, Joel F. Andrews, Annelise M. Wilhite, Steven McClellan, Ileana Aragon, Antonio B. Ward, Xi Chen, Adam B. Keeton, Kristy Berry, Gary A. Piazza, Jennifer M. Scalici, Luciana Madeira da Silva
Publikováno v:
Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-17 (2022)
Abstract A leading theory for ovarian carcinogenesis proposes that inflammation associated with incessant ovulation is a driver of oncogenesis. Consistent with this theory, nonsteroidal anti-inflammatory drugs (NSAIDs) exert promising chemopreventive
Externí odkaz:
https://doaj.org/article/7aeee746c49843a59c7f588c890c9c9e
Autor:
Christopher A. Koczor, Kate M. Saville, Joel F. Andrews, Jennifer Clark, Qingming Fang, Jianfeng Li, Rasha Q. Al-Rahahleh, Md Ibrahim, Steven McClellan, Mikhail V. Makarov, Marie E. Migaud, Robert W. Sobol
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109917- (2021)
Summary: Assembly and disassembly of DNA repair protein complexes at DNA damage sites are essential for maintaining genomic integrity. Investigating factors coordinating assembly of the base excision repair (BER) proteins DNA polymerase β (Polβ) an
Externí odkaz:
https://doaj.org/article/6a82efe53d94463fb399bda39a6d5f71
Autor:
Arthur E. Frankel MD, Sachin Deshmukh PhD, Amit Reddy MD, John Lightcap PhD, Maureen Hayes, Steven McClellan, Seema Singh PhD, Brooks Rabideau PhD, T. Grant Glover PhD, Bruce Roberts PhD, Andrew Y. Koh MD
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
The past decade has seen tremendous advances in both our understanding of cancer immunosuppressive microenvironments and colonic bacteria facilitated by immune checkpoint inhibitor antibodies and next generation sequencing, respectively. Because an i
Externí odkaz:
https://doaj.org/article/aad2bd1ca75c42c481cbc7b4e261abbb
Autor:
Ritu Arora, Clayton Yates, Bernard D Gary, Steven McClellan, Ming Tan, Yaguang Xi, Eddie Reed, Gary A Piazza, Laurie B Owen, Windy Dean-Colomb
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98370 (2014)
BACKGROUND:Triple-negative breast cancer (TNBC) is a highly diverse group that is associated with an aggressive phenotype. Its treatment has been challenging due to its heterogeneity and absence of well-defined molecular targets. Thus, there is an ur
Externí odkaz:
https://doaj.org/article/6d806862270943d79e0000e9aee3c223
Autor:
Sumit Arora, Arun Bhardwaj, Sanjeev K Srivastava, Seema Singh, Steven McClellan, Bin Wang, Ajay P Singh
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21573 (2011)
Survival rates for patients with pancreatic cancer are extremely poor due to its asymptomatic progression to advanced and metastatic stage for which current therapies remain largely ineffective. Therefore, novel therapeutic agents and treatment appro
Externí odkaz:
https://doaj.org/article/47ff7806b8cd4f9dade32bf04c9a80a3
Autor:
Ming Tan, Oystein Fodstad, Gary A. Piazza, Wensheng Lin, Yifeng Lin, Steven McClellan, Tung Vu, David C. Schmitt, Joshua B. Phillips, Zixing Liu, Ritu Arora, Luciana Madeira da Silva, Hao Liu, Sangbin Lim
B7-H3 is a member of B7 family of immunoregulatory transmembrane glycoproteins expressed by T cells. While B7-H3 overexpression is associated with poor outcomes in multiple cancers, it also has immune-independent roles outside T cells and its precise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064abd0554c56d9595caad8a2d475c62
https://doi.org/10.1158/0008-5472.c.6508131
https://doi.org/10.1158/0008-5472.c.6508131
Autor:
Ming Tan, Oystein Fodstad, Gary A. Piazza, Wensheng Lin, Yifeng Lin, Steven McClellan, Tung Vu, David C. Schmitt, Joshua B. Phillips, Zixing Liu, Ritu Arora, Luciana Madeira da Silva, Hao Liu, Sangbin Lim
Fig. S1: Glucose uptake and lactate production in B7-H3 knockdown Fig. S2: Growth inhibition W/O B7-H3 Fig S3: Proliferation assay in glucose deprivation. Fig. S4: Expression in B7-H3 knockdown w/o CoCl2. Fig. S5: mRNA levels. Fig. S6: Reduction of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09eb9b21202d1b0db830f93ef424dd2e
https://doi.org/10.1158/0008-5472.22411032.v1
https://doi.org/10.1158/0008-5472.22411032.v1
Autor:
Ming Tan, Oystein Fodstad, Gary A. Piazza, Wensheng Lin, Yifeng Lin, Steven McClellan, Tung Vu, David C. Schmitt, Joshua B. Phillips, Zixing Liu, Ritu Arora, Luciana Madeira da Silva, Hao Liu, Sangbin Lim
Legends for Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd85b1322d968885db1de21e1164be6
https://doi.org/10.1158/0008-5472.22411035.v1
https://doi.org/10.1158/0008-5472.22411035.v1
Autor:
Jianfeng, Li, Christopher A, Koczor, Kate M, Saville, Faisal, Hayat, Alison, Beiser, Steven, McClellan, Marie E, Migaud, Robert W, Sobol
Publikováno v:
Cancers. 14(15)
Glioblastoma multiforme (GBM) is an incurable brain cancer with an average survival of approximately 15 months. Temozolomide (TMZ) is a DNA alkylating agent for the treatment of GBM. However, at least 50% of the patients treated with TMZ show poor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e445ed0696825c58be60f19cabb25ee8
https://pubmed.ncbi.nlm.nih.gov/35892832
https://pubmed.ncbi.nlm.nih.gov/35892832
Publikováno v:
Cancer Research. 83:1424-1424
Introduction: Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide. The balance between cancer cell proliferation and apoptosis, which maintains intestinal epithelial cell homeostasis, is disturbed in CRC. Furthermore, deregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0999af8577c5b808fc763ee6739fe0d
https://doi.org/10.1158/1538-7445.am2023-1424
https://doi.org/10.1158/1538-7445.am2023-1424