Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Steven Mark Dunn"'
1
Akademický článek
From bench to bedside: 64Cu/177Lu 1C1m-Fc anti TEM-1: mice-to-human dosimetry extrapolations for future theranostic applications
Autor: Silvano Gnesin, Nicolas Chouin, Michel Cherel, Steven Mark Dunn, Niklaus Schaefer, Alain Faivre-Chauvet, John O. Prior, Judith Anna Delage
Publikováno v: EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The development of diagnostic and therapeutic radiopharmaceuticals is an hot topic in nuclear medicine. Several radiolabeled antibodies are under development necessitating both biokinetic and dosimetry extrapolations for effective human tran
Externí odkaz: https://doaj.org/article/675c9d24f452478b9c0e94b40b313ada
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2
Akademický článek
Impact of DOTA Conjugation on Pharmacokinetics and Immunoreactivity of [177Lu]Lu-1C1m-Fc, an Anti TEM-1 Fusion Protein Antibody in a TEM-1 Positive Tumor Mouse Model
Autor: Judith Anna Delage, Alain Faivre-Chauvet, Jacques Barbet, Julie Katrin Fierle, Niklaus Schaefer, George Coukos, David Viertl, Steven Mark Dunn, Silvano Gnesin, John O. Prior
Publikováno v: Pharmaceutics, Vol 13, Iss 1, p 96 (2021)
1C1m-Fc, an anti-tumor endothelial marker 1 (TEM-1) scFv-Fc fusion protein antibody, was previously successfully radiolabeled with 177Lu. TEM-1 specific tumor uptake was observed together with a non-saturation dependent liver uptake that could be rel
Externí odkaz: https://doaj.org/article/b9a323a8b9be4b5b9e09a874af5200aa
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3
Akademický článek
From bench to bedside: 64Cu/177Lu 1C1m-Fc anti TEM-1: mice-to-human dosimetry extrapolations for future theranostic applications.
Autor: Gnesin, Silvano1 (AUTHOR), Chouin, Nicolas2 (AUTHOR), Cherel, Michel3 (AUTHOR), Dunn, Steven Mark4 (AUTHOR), Schaefer, Niklaus5 (AUTHOR), Faivre-Chauvet, Alain3 (AUTHOR), Prior, John O.5 (AUTHOR) John.Prior@chuv.ch, Delage, Judith Anna6 (AUTHOR)
Publikováno v: EJNMMI Research. 6/14/2023, Vol. 13 Issue 1, p1-11. 11p.
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4
Akademický článek
Copper-64-Labeled 1C1m-Fc, a New Tool for TEM-1 PET Imaging and Prediction of Lutetium-177-Labeled 1C1m-Fc Therapy Efficacy and Safety.
Autor: Delage, Judith Anna1 (AUTHOR) judith.delage@chuv.ch, Gnesin, Silvano2 (AUTHOR) silvano.gnesin@chuv.ch, Prior, John O.3 (AUTHOR) judith.delage@chuv.ch, Barbet, Jacques4 (AUTHOR) jacques.barbet@univ-nantes.fr, Le Saëc, Patricia5 (AUTHOR) patricia.lesaec@univ-nantes.fr, Marionneau-Lambot, Séverine5 (AUTHOR) severine.marionneau-lambot@univ-nantes.fr, Gouard, Sébastien5 (AUTHOR) sebastien.gouard@univ-nantes.fr, Chérel, Michel5 (AUTHOR) michel.cherel@univ-nantes.fr, Bourgeois, Mickael4 (AUTHOR) mickael.bourgeois@univ-nantes.fr, Schaefer, Niklaus3 (AUTHOR), Viertl, David6,7 (AUTHOR) david.viertl@chuv.ch, Fierle, Julie Katrin8 (AUTHOR) julie.fierle@unil.ch, Dunn, Steven Mark8 (AUTHOR) steven.dunn@chuv.ch, Faivre-Chauvet, Alain5 (AUTHOR) alain.faivre-chauvet@univ-nantes.fr
Publikováno v: Cancers. Dec2021, Vol. 13 Issue 23, p5936. 1p.
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5
Akademický článek
Impact of DOTA Conjugation on Pharmacokinetics and Immunoreactivity of [ 177 Lu]Lu-1C1m-Fc, an Anti TEM-1 Fusion Protein Antibody in a TEM-1 Positive Tumor Mouse Model.
Autor: Delage, Judith Anna1 (AUTHOR) judith.delage@chuv.ch, Faivre-Chauvet, Alain2 (AUTHOR) alain.faivre-chauvet@univ-nantes.fr, Barbet, Jacques3 (AUTHOR) jacques.barbet@univ-nantes.fr, Fierle, Julie Katrin4 (AUTHOR) julie.fierle@unil.ch, Schaefer, Niklaus5 (AUTHOR) niklaus.schaefer@chuv.ch, Coukos, George6 (AUTHOR) george.coukos@chuv.ch, Viertl, David5 (AUTHOR) david.viertl@chuv.ch, Dunn, Steven Mark4 (AUTHOR) steven.dunn@chuv.ch, Gnesin, Silvano7 (AUTHOR) silvano.gnesin@chuv.ch, Prior, John O.5 (AUTHOR) judith.delage@chuv.ch
Publikováno v: Pharmaceutics. Jan2021, Vol. 13 Issue 1, p96. 1p.
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