Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steven M. Yannone"'
Autor:
Fengtao Su, Shibani Mukherjee, Yanyong Yang, Eiichiro Mori, Souparno Bhattacharya, Junya Kobayashi, Steven M. Yannone, David J. Chen, Aroumougame Asaithamby
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1387-1401 (2014)
WRN, the protein defective in Werner syndrome (WS), is a multifunctional nuclease involved in DNA damage repair, replication, and genome stability maintenance. It was assumed that the nuclease activities of WRN were critical for these functions. Here
Externí odkaz:
https://doaj.org/article/9d9fc5675c0d4bcfaa8258bf05452789
Autor:
Felice C. Lightstone, Greg L. Hura, Steven M. Yannone, Xiaoyu Hu, Hal S. Padgett, Matthew Mcgee, David S. Shin, John A. Tainer, Henry Y. H. Tang, Yue Yang
Publikováno v:
Biochemistry. 57:6688-6700
Protein engineering to alter recognition underlying ligand binding and activity has enormous potential. Here, ligand binding for Escherichia coli phosphoenolpyruvate carboxykinase (PEPCK), which converts oxaloacetate into CO(2) and phosphoenolpyruvat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9a1656dc04d3ecea8fd853daf77967
https://doi.org/10.1021/acs.biochem.8b00963
https://doi.org/10.1021/acs.biochem.8b00963
Autor:
Jean-Philippe Coppe, Funda Vakar-Lopez, Denise P. Muñoz, Adam Freund, Pierre Yves Desprez, David H. Raulet, Peter S. Nelson, Francis Rodier, Misako Kawahara, Judith Campisi, Jennifer D. Wu, Steven M. Yannone, Anneleen Daemen, Yu Sun, Laura J. van't Veer
Publikováno v:
JCI insight, vol 5, iss 14
Cellular senescence is a tumor-suppressive mechanism that can paradoxically contribute to aging pathologies. Despite evidence of immune clearance in mouse models, it is not known how senescent cells (SnCs) persist and accumulate with age or in tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6c498f1af7422fa4bf01f566b83143
https://escholarship.org/uc/item/015092m5
https://escholarship.org/uc/item/015092m5
Autor:
Hirohiko Yajima, David J. Chen, Yanyong Yang, Aroumougame Asaithamby, Steven M. Yannone, Subroto Ghose, Souparno Bhattacharya, Salim Abdisalaam, Ritu Mishra, Fengtao Su, Kalayarasan Srinivasan, Shibani Mukherjee
Publikováno v:
Oncotarget
Faithful and complete genome replication in human cells is essential for preventing the accumulation of cancer-promoting mutations. WRN, the protein defective in Werner syndrome, plays critical roles in preventing replication stress, chromosome insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b19620f015df58e5cd43804c9f0334
https://doi.org/10.18632/oncotarget.6659
https://doi.org/10.18632/oncotarget.6659
Autor:
Gary Siuzdak, Gary J. Patti, Zheng-Jiang Zhu, Caroline H. Johnson, Junhua Wang, Steven M. Yannone, Andrew Schultz
Publikováno v:
Nature Protocols. 8:451-460
Untargeted metabolomics provides a comprehensive platform for identifying metabolites whose levels are altered between two or more populations. By using liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS), hundreds to thou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd17538c2e0fc09230d9767915af7878
https://doi.org/10.1038/nprot.2013.004
https://doi.org/10.1038/nprot.2013.004
Autor:
Sri Lakshmi Chalasani, Matthew C. T. Hartman, Lawrence F. Povirk, Steven M. Yannone, Konstantin Akopiants, Mohammed Almohaini, Tong Zhou, Duaa Bafail, Dale A. Ramsden
DNA double-strand breaks induced by ionizing radiation are often accompanied by ancillary oxidative base damage that may prevent or delay their repair. In order to better define the features that make some DSBs repair-resistant, XLF-dependent nonhomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dba4be206935154e70784f4963b116a
https://europepmc.org/articles/PMC4851560/
https://europepmc.org/articles/PMC4851560/
Autor:
Milton T. Stubbs, Ross W. Walton, Peter Hwu, Robert M. Glaeser, Bong-Gyoon Han, Amos Song, Ming Dong, Pablo Arbeláez, Steven M. Yannone
Publikováno v:
Journal of Structural Biology. 180:249-253
Chemical biotinylation of protein complexes followed by binding to two-dimensional (monolayer) crystals of streptavidin is shown to be an effective way to prepare cryo-EM specimens from samples at low protein concentration. Three different multiprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fb249f8343e561749b3749e2213f93
https://doi.org/10.1016/j.jsb.2012.04.025
https://doi.org/10.1016/j.jsb.2012.04.025
Publikováno v:
Current Opinion in Biotechnology. 23:89-95
The vital nature of metal uptake and balance in biology is evident in the highly evolved strategies to facilitate metal homeostasis in all three domains of life. Several decades of study on metals and metalloproteins have revealed numerous essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d04bb602d22a989ab89c68e858218f
https://doi.org/10.1016/j.copbio.2011.11.005
https://doi.org/10.1016/j.copbio.2011.11.005
Autor:
J. Christopher Bare, Min Pan, Joseph Slagel, David J Reiss, Sujung Lim, Robert L. Moritz, Steven M. Yannone, Murray Hackett, John A. Leigh, Sung Ho Yoon, Nitin S. Baliga, Dan Tenenbaum, Michael W. W. Adams, Angeli Lal Menon, Adam Barnebey
Publikováno v:
Genome Research. 21:1892-1904
Assembly of genes into operons is generally viewed as an important process during the continual adaptation of microbes to changing environmental challenges. However, the genome reorganization events that drive this process are also the roots of insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6e89a8dfef6c009698e6899abc161e
https://doi.org/10.1101/gr.122218.111
https://doi.org/10.1101/gr.122218.111
Publikováno v:
Nucleic Acids Research
Deficiency in Artemis is associated with lack of V(D)J recombination, sensitivity to radiation and radiomimetic drugs, and failure to repair a subset of DNA double-strand breaks (DSBs). Artemis harbors an endonuclease activity that trims both 5'- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453503f5ff98715044f36dcd69dfd39e
https://doi.org/10.1093/nar/gkr257
https://doi.org/10.1093/nar/gkr257