Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Steven M. Walker"'
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Supplementary Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9837817e7906381d03da436c4c0aba83
https://doi.org/10.1158/1078-0432.22479923
https://doi.org/10.1158/1078-0432.22479923
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Figures S1-S9, Tables S1, S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496cf180498237ddd1cd669c0717922a
https://doi.org/10.1158/1078-0432.22479920
https://doi.org/10.1158/1078-0432.22479920
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Purpose:The DNA damage immune response (DDIR) assay was developed in breast cancer based on biology associated with deficiencies in homologous recombination and Fanconi anemia pathways. A positive DDIR call identifies patients likely to respond to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b0d147fbbb30b1796bb72b6461704c
https://doi.org/10.1158/1078-0432.c.6530324.v1
https://doi.org/10.1158/1078-0432.c.6530324.v1
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3561136117c96a00b0726edbd0837c50
https://doi.org/10.1158/1078-0432.22479926.v1
https://doi.org/10.1158/1078-0432.22479926.v1
Autor:
Richard D. Kennedy, Kevin M. Prise, D. Paul Harkin, Clark Chen, Karl T. Butterworth, Kienan I. Savage, Katarina Wikstrom, Jie Li, David Gonda, Steven M. Walker, Conor Hanna, Nuala McCabe
Supplementary Methods and Table 1. Supplementary Table 1: siRNA target genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843a5d95397c294d8fc2440ecb285426
https://doi.org/10.1158/0008-5472.22406378
https://doi.org/10.1158/0008-5472.22406378
Autor:
Richard D. Kennedy, Kevin M. Prise, D. Paul Harkin, Clark Chen, Karl T. Butterworth, Kienan I. Savage, Katarina Wikstrom, Jie Li, David Gonda, Steven M. Walker, Conor Hanna, Nuala McCabe
Ataxia telangiectasia mutated (ATM) is an important signaling molecule in the DNA damage response (DDR). ATM loss of function can produce a synthetic lethal phenotype in combination with tumor-associated mutations in FA/BRCA pathway components. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275637bd398ba31060294bd2db732e4a
https://doi.org/10.1158/0008-5472.c.6507065.v1
https://doi.org/10.1158/0008-5472.c.6507065.v1
Autor:
Richard D. Kennedy, Kevin M. Prise, D. Paul Harkin, Clark Chen, Karl T. Butterworth, Kienan I. Savage, Katarina Wikstrom, Jie Li, David Gonda, Steven M. Walker, Conor Hanna, Nuala McCabe
Supplementary Figures 1-4. Figure 1: ATM is a potential drug target for PTEN-deficient cells Figure 2: The synthetic lethality with PTEN loss and ATM inhibition is independent of AKT function Figure 3: The synthetic lethality with PTEN loss and ATM i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399c47a3b2804e0291e9d59ccc782a23
https://doi.org/10.1158/0008-5472.22406381
https://doi.org/10.1158/0008-5472.22406381
Autor:
Steven M. Walker, Daryl Watkins
Toxic Leadership: Research and Cases presents research and cases on toxic leadership that emerged from qualitative research on the followers of toxic leaders. The goal is to help students, researchers, and academics understand how toxic leadership em
Autor:
Tim Maughan, Matthew T. Seymour, Korsuk Sirinukunwattana, Enric Domingo, Andrew D Beggs, Viktor H. Koelzer, Andrew Blake, Celina Whalley, Graeme I. Murray, Steven M Walker, Claire Hardy, Clare Verrill, Aikaterini Chatzipli, Ian Tomlinson, Jens Rittscher, Philip D. Dunne, Chieh-Hsi Wu, Leslie Samuel, Philip Quirke, Keara L Redmond, Angela A Meade, Ultan McDermott, Susan D. Richman, Simon J. Leedham
Objective Complex phenotypes captured on histological slides represent the biological processes at play in individual cancers, but the link to underlying molecular classification has not been clarified or systematised. In colorectal cancer (CRC), his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c707e612d508812b17dc873ea732c4
Autor:
Steven M. Walker
Publikováno v:
Futures Thinking and Organizational Policy ISBN: 9783319949222
This case describes how a leader of a financial institution used systems thinking as a foresight tool to help survive global economic crisis during the Great Recession of 2008. Due to the leader’s systems thinking perspective, several behavioral th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50799885e693f26ca5b0c641116aa611
https://doi.org/10.1007/978-3-319-94923-9_13
https://doi.org/10.1007/978-3-319-94923-9_13