Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Steven M. Rothman"'
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 637-643 (2006)
Cooling is a potential treatment for several neurological diseases. We have examined rodent and cat neocortex, cooled to 5 and 3°C, respectively, to identify a lower limit for safely cooling brain. Rat neocortex, intermittently cooled with a thermoe
Externí odkaz:
https://doaj.org/article/de9f1bf4844d4681a58b473899968304
Autor:
Shuli Xia, Zu Yun Cai, Liu Lin Thio, Jeong Sook Kim-Han, Laura L. Dugan, Douglas F. Covey, Steven M. Rothman
Publikováno v:
Neurobiology of Disease, Vol 9, Iss 3, Pp 282-293 (2002)
We synthesized an estrogen analog, ZYC-5, lacking activity at the classical estrogen receptor and examined its neuroprotective potential against necrosis induced by N-methyl-d-aspartate (NMDA) and apoptosis/necrosis induced by the NMDA receptor antag
Externí odkaz:
https://doaj.org/article/4d50ae677f1c41dfb513448688d11746
Publikováno v:
Neurobiology of Disease, Vol 3, Iss 4, Pp 287-298 (1997)
Mitochondrial encephalomyopathies arise from mutations in the mitochondrial or nuclear genome and result in defective energy metabolism. Investigation of cellular pathophysiology in these disorders has been limited to nonneuronal explant cultures suc
Externí odkaz:
https://doaj.org/article/9afc2cd7448b499b977e4c8c1f791586
Autor:
Sarah W. Alander, Steven M. Rothman
Publikováno v:
Pediatric Emergency Care. 34:102-105
We aimed to characterize the utility of neuroimaging for head trauma in a suburban community hospital and determine whether imaging practices conform to most recent pediatric guidelines. The electronic medical record was surveyed for computed tomogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9970cb4db3e94423fc92213dc3bf8014
https://doi.org/10.1097/pec.0000000000000683
https://doi.org/10.1097/pec.0000000000000683
Publikováno v:
Epilepsy Research. 117:17-22
Seletracetam (SEL), an analog of the antiepileptic drug levetiracetam (LEV), decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A with a higher affinity than LEV. Experiments were performed to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269343eec26cda86a857182858acb4b2
https://doi.org/10.1016/j.eplepsyres.2015.08.006
https://doi.org/10.1016/j.eplepsyres.2015.08.006
Autor:
William D. Graf, Dan Larriviere, Geoffrey P. Miller, Saskia K. Nagel, Steven M. Rothman, Leon G. Epstein
Publikováno v:
Neurology. 80:1251-1260
The use of prescription medication to augment cognitive or affective function in healthy persons—or neuroenhancement—is increasing in adult and pediatric populations. In children and adolescents, neuroenhancement appears to be increasing in paral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd075049d278646bcc02b06bd1e6ebe
https://doi.org/10.1212/wnl.0b013e318289703b
https://doi.org/10.1212/wnl.0b013e318289703b
Autor:
Steven M. Rothman, Derek R. Verley, John W. Miller, Jeffrey G. Ojemann, Clifford L. Eastman, Hui Wen Wilkerson, Felix Darvas, Federico M. Farin, Nancy R. Temkin, Jason S. Fender, Raimondo D'Ambrosio, Matthew D. Smyth
Publikováno v:
Annals of Neurology. 73:199-209
Objective Post-traumatic epilepsy is prevalent, often difficult to manage, and currently cannot be prevented. Although cooling is broadly neuroprotective, cooling-induced prevention of chronic spontaneous recurrent seizures has never been demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ac4f96a8155631a7e2e47cbeed01fb
https://doi.org/10.1002/ana.23764
https://doi.org/10.1002/ana.23764
Autor:
Matthew D. Smyth, Steven M. Rothman, Karen Steger-May, Hussan S. Mohammed, Rebecca Munro, Robert L. Grubb, David D. Limbrick, Judith L.Z. Weisenberg, Christian B. Kaufman
Publikováno v:
Epilepsia. 53:712-720
Summary Purpose: The short-term efficacy and safety of epilepsy surgery relative to medical therapy has been established, but it remains underutilized. There is a lack of data regarding the long-term seizure-control rates and quality of life outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e207409d4a25288c1f5fd42f7eb8c3
https://doi.org/10.1111/j.1528-1167.2011.03398.x
https://doi.org/10.1111/j.1528-1167.2011.03398.x
Publikováno v:
Epilepsia. 53:469-476
SUMMARY Purpose: Previous work has shown that levetiracetam (LEV) binds the vesicular protein SV2A and reduces excitatory neurotransmitter release during trains of highfrequency activity, most likely by accessing its binding site through vesicular en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4c793cb6f9fd9e96ce5b4faaa472f9a
https://doi.org/10.1111/j.1528-1167.2011.03392.x
https://doi.org/10.1111/j.1528-1167.2011.03392.x
Publikováno v:
Pediatric Neurology. 43:49-52
Wegener's granulomatosis is a necrotizing, granulomatous vasculitis that primarily affects the respiratory tract and kidneys. It is rare in children. Few pediatric and adult case reports described seizures and central nervous system involvement at in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40857ada9a37fdcfa87afef863969ac8
https://doi.org/10.1016/j.pediatrneurol.2010.03.014
https://doi.org/10.1016/j.pediatrneurol.2010.03.014