Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Steven M. Podos"'
Publikováno v:
Acta Ophthalmologica. 62:142-149
Of 59 phakic eyes with open-angle glaucoma initially treated with laser trabeculoplasty, 45 eyes were followed at least 6 months. Intraocular pressure (IOP) at 6 months was less than 22 mmHg in 37 (82%), of which 25 (81%) were on fewer medications; o
Publikováno v:
Acta Ophthalmologica. 56:6-10
A controlled trial was instituted to compare the effect on intraocular pressure of topical administration of timolol maleate with epinephrine hydrochloride. A bottling error by the manufacturer resulted in the placebo bottles containing 1.5% timolol
Publikováno v:
Journal of Glaucoma. 17:73-78
To evaluate the effects of flunarizine, a nonselective calcium channel blocker, on intraocular pressure (IOP) in monkeys with laser-induced unilateral glaucoma and on aqueous humor dynamics in normal monkeys.The IOP was measured before and hourly for
Autor:
Lin Guo, Xuyang Liu, Haiyan Wang, Steven M. Podos, Paul L. Kaufman, B'Ann T. Gabelt, Ping-Yu Lee, Ningli Wang
Publikováno v:
Current Eye Research. 32:843-850
To determine the effects of misakinolide (MISA) A, which leads to the disassembly of actin filaments, on the actin cytoskeleton of cultured human trabecular meshwork (HTM) cells and on intraocular pressure (IOP) in living rats and monkeys.Cultured HT
Autor:
John Danias, David Goldblum, Fran Shen, YL Su, Steven M. Podos, Scott E. Brodie, Maria-Florencia Zamora, Manolis Kavalarakis, Kevin C. Lee, Thom Mittag, Bin Chen
Publikováno v:
Experimental Eye Research. 82:219-228
Episcleral vein cauterization (EVC) is used in rats to generate a glaucoma model with high intraocular pressure (IOP). The long-term retinal damage in this glaucoma model, however, has not been accurately quantified. We report the location and amount
Publikováno v:
Experimental Eye Research. 80:629-632
To evaluate the effect of CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure (IOP) in monkey eyes with unilateral laser-induced glaucoma. A multiple-dose study was performed in 8 glaucomatous monkey eyes. One 50 microl drop of CS
Publikováno v:
Survey of Ophthalmology. 45:S277-S283
Apoptosis may contribute to retinal ganglion cell loss in glaucoma and glaucoma models. Recent research has suggested that mitochondrially dependent apoptosis signaling may contribute to apoptosis in a rat model of glaucoma involving chronic increase
Publikováno v:
Journal of Glaucoma. 9:458-462
To investigate the additive ocular hypotensive effect of brimonidine, dorzolamide, latanoprost, or artificial tears to timolol in monkey eyes with laser-induced unilateral glaucoma.Eight monkeys were used and each animal received all four combination
Publikováno v:
Molecular and Cellular Biochemistry. 204:11-16
The divalent cation requirements of NOS activity in bovine retina homogenate supernatant were investigated. Supernatants were assayed under standard conditions (in mM: EDTA 0.45, Ca2+ 0.25, Mg2+ 4.0). In order to investigate the enzyme's dependence o
Autor:
Thom Mittag, Scott E. Brodie, Andreas U. Bayer, Klaus-Peter Maag, Philip Cook, Steven M. Podos
Publikováno v:
Documenta Ophthalmologica. 98:233-246
To compare corneal electrodes commonly used in rodent eyes for repeat and left versus right eye accuracy and variability to record the flash electroretinogram (ERG). Animals studied were eight C57BL/6 mice and eight rats of the Wistar strain. Scotopi