Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Steven M. Goldfine"'
Publikováno v:
Cardiology. 90:101-109
Myocardial fibrosis and myocyte degeneration have been reported in patients with chronic aortic regurgitation (AR), and may be related to the pathophysiology of congestive heart failure (CHF) in this disease. To define the relationship between myocar
Autor:
Mark Morgan, Edmund M. Herrold, Raffaele Gentile, Jeffrey S. Borer, Steven M. Goldfine, Pat B. Zanzonico, NM Magid, Ruth Hardoff, Ping Lu
Publikováno v:
Journal of Nuclear Cardiology. 4:25-32
Fiber dropout and myocyte necrosis precede heart failure in experimental aortic regurgitation (AR). The current study aimed to determine whether this process can be detected by noninvasive scintigraphic imaging. 111In-labeled antimyosin antibody Fab
Autor:
Robert S. Lees, Brian R. Moyer, Jeffrey S. Borer, John Lister-James, Ann M. Lees, Steven M. Goldfine, Edmund M. Herrold, Ping Lu, Pat Zanzonico, Richard T. Dean
Publikováno v:
American Journal of Therapeutics. 3:673-680
I-125 labeled SP4 is a synthetic oligopeptide derived from apolipoprotein B of low-density lipoprotein that has been shown to localized in atherosclerotic plaques in experimental animals. However, its biodistribution and mechanism of localization nee
Autor:
Edmund M. Herrold, Clare Hochreiter, John N. Carter, Sharada L. Truter, Steven M. Goldfine, Jeffrey S. Borer
Publikováno v:
Basic Science for the Cardiologist ISBN: 9780792386025
Regurgitant valvular heart diseases and, most particularly, insufficiency of the aortic and/or mitral valves (AR, MR), are among the more common, and most predictable, causes of congestive heart failure. Current data suggest that these conditions als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b101ba1630029234309db67b1bc8fbd7
https://doi.org/10.1007/978-0-585-38141-1_3
https://doi.org/10.1007/978-0-585-38141-1_3
Publikováno v:
Computers in Cardiology 1994.
In severe, chronic aortic regulation (AR) in man, systolic pressure time interval and diastolic pressure time interval measurements suggest an abnormal load-to-endocardial blood flow relationship. To better define this relationship, the authors exten
Autor:
Edmund M. Herrold, N.M. Magid, Steven M. Goldfine, Hua Zhou, Pat Zanzonico, S. Nakayama, A. J. L. Cooper, Jeffrey S. Borer
Publikováno v:
Computers in Cardiology 1994.
The authors have developed a 3-compartment model for determining the distribution of label derived from L-[l-/sup 14/C]leucine (LEU) in myocardial tissue. The 3 compartments are the pools of tissue precursor (i.e. free) LEU, protein-incorporated leuc
Autor:
Edmund M. Herrold, Massimiliano Szulc, Steven M. Goldfine, Jeffrey S. Borer, N.M. Magid, Pat Zanzonico, Ping Lu
Publikováno v:
Computers in Cardiology 1995.
We have previously shown that left ventricular (LV) shape transformation (from ellipsoid toward spherical) may modulate abnormal myocardial wall stresses occurring as a result of chronic severe aortic regurgitation (AR). If so then the extent of sphe
Myocardial connexin43 expression in left ventricular hypertrophy resulting from aortic regurgitation
Publikováno v:
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 8(1)
Intercellular conduction in the working myocardium of the mammalian heart is mediated by gap junctions composed of connexin43 or 45. Recently, it has been shown that myocardial connexin expression is malleable and may be altered with disease. To bett
Publikováno v:
American journal of therapeutics. 5(3)
Myocardial fibrosis and abnormal myocardial collagen content are common in many forms of pathological cardiac hypertrophy, including that mediated by pressure overload. Recently, in an experimental animal model of chronic aortic regurgitation (AR), w
Publikováno v:
American journal of therapeutics. 5(6)
Vesnarinone, a quinoline derivative with modest positive inotropic action, has been shown in several studies to benefit patients with clinical congestive heart failure. The cellular basis of its clinical benefit is not known, although the drug has se