Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Steven M. Erb"'
Genetic Adaptation by Dengue Virus Serotype 2 to Enhance Infection of Aedes aegypti Mosquito Midguts
Publikováno v:
Viruses, Vol 14, Iss 7, p 1569 (2022)
Dengue viruses (DENVs), serotypes 1–4, are arthropod-borne viruses transmitted to humans by mosquitoes, primarily Aedes aegypti. The transmission cycle begins when Ae. aegypti ingest blood from a viremic human and the virus infects midgut epithelia
Externí odkaz:
https://doaj.org/article/eb6e14df614b47c3af4df3df0f058344
Autor:
Paul Nelson, Ashaben Patel, Ravi S. Shukla, Jill A Livengood, Steven M. Erb, David B. Volkin, Ozan S. Kumru, Lee M. Smith, Strange Linda Marie, Sangeeta B. Joshi
Publikováno v:
Vaccine. 36(22)
A combination experimental approach, utilizing semi-empirical excipient screening followed by statistical modeling using design of experiments (DOE), was undertaken to identify stabilizing candidate formulations for a lyophilized live attenuated Flav
Autor:
Betty E. Luy, Siritorn Butrapet, Kelley J. Moss, Thomas Childers, Carol D. Blair, John T. Roehrig, Amanda E. Calvert, Steven M. Erb, Claire Y.-H. Huang
Publikováno v:
Virology. 413:118-127
Fifteen mutant dengue viruses were engineered and used to identify AAs in the molecular hinge of the envelope protein that are critical to viral infection. Substitutions at Q52, A54, or E133 reduced infectivity in mammalian cells and altered the pH t
Autor:
Siritorn Butrapet, John T. Roehrig, Kelly J. Moss, Claire Y.-H. Huang, Shawn J. Silengo, Thomas Childers, Richard M. Kinney, Steven M. Erb, Amanda E. Calvert, Carol D. Blair
Publikováno v:
Virology. 396:305-315
The flaviviral envelope (E) protein directs virus-mediated membrane fusion. To investigate membrane fusion as a requirement for virus growth, we introduced 27 unique mutations into the fusion peptide of an infectious cDNA clone of dengue 2 virus and
Autor:
Tung Nguyen, Li-Mei Chen, Xui Hua Lu, Sherif R. Zaki, Chun Kang, Jae Hong Kim, Long T. Hoang, Jeannette Guarner, Sunthareeya Waicharoen, Nancy J. Cox, Pranee Thawatsupha, Steven M. Erb, Lindsay Edwards, Patricia W. Greer, Kristy J. Szretter, Doan C. Nguyen, Terrence M. Tumpey, Malinee Chittaganpitch, Lien S. Phuong, Jacqueline M. Katz, Wilina Lim, Diep T. Nguyen, Taronna R. Maines, Ruben O. Donis, Hanh T. Nguyen
Publikováno v:
Journal of Virology. 79:11788-11800
The spread of highly pathogenic avian influenza H5N1 viruses across Asia in 2003 and 2004 devastated domestic poultry populations and resulted in the largest and most lethal H5N1 virus outbreak in humans to date. To better understand the potential of
Autor:
Thomas Childers, John T. Roehrig, Steven M. Erb, Amanda E. Calvert, Carol D. Blair, Shawn J. Silengo, Siritorn Butrapet, Betty E. Luy, Claire Y.-H. Huang, Kelley J. Moss
Publikováno v:
Virology. (2):328-335
The FG extended loop in domain III of the dengue virus type 2 (DENV2) envelope protein is postulated to be a molecular determinant for host cell infectivity. To determine the contribution of the FG loop to virus infectivity, an infectious cDNA clone
Autor:
Anucha Apisarnthanarak, Piyaporn Apisarnthanarak, Steven M. Erb, Sunthareeya Waicharoen, Malinee Chittaganpitch, Somchai Sangkitporn, Iain Stephenson, Rungruang Kitphati, Victoria J. Fraser, Linda M. Mundy, Jacqueline M. Katz, Uayporn Pinitchai, Pranee Thawatsupha
Publikováno v:
Scopus-Elsevier
After the initial atypical presentation of a patient with avian influenza (H5N1) infection, paired acute-phase and convalescent-phase serum samples obtained from 25 health care workers (HCWs) who were exposed to the patient were compared with paired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1050577dc355d3cd8abff5c56528ec78
http://www.scopus.com/inward/record.url?eid=2-s2.0-29644443464&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-29644443464&partnerID=MN8TOARS