Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Steven M Taffet"'
Autor:
Mingliang Zhang, Chantal J. M. van Opbergen, Maartje Noorman, Harold V.M. van Rijen, Mario Delmar, Sarah H. Vermij, Anna Pfenniger, Jacques M.T. de Bakker, Marc A. Vos, Zhen Li, Roel van der Nagel, Aaron Glass, Jaël S Copier, Steven M. Taffet, Toon A.B. van Veen, Peter J. Mohler
Publikováno v:
International journal of molecular sciences, 20(17). Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4076 (2019)
International Journal of Molecular Sciences
van Opbergen, Chantal J M; Noorman, Maartje; Pfenniger, Anna; Copier, Jaël S; Vermij, Sarah H.; Li, Zhen; van der Nagel, Roel; Zhang, Mingliang; de Bakker, Jacques M T; Glass, Aaron M; Mohler, Peter J; Taffet, Steven M; Vos, Marc A; van Rijen, Harold V M; Delmar, Mario; van Veen, Toon A B (2019). Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress. International journal of molecular sciences, 20(17) Molecular Diversity Preservation International MDPI 10.3390/ijms20174076
Volume 20
Issue 17
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4076 (2019)
International Journal of Molecular Sciences
van Opbergen, Chantal J M; Noorman, Maartje; Pfenniger, Anna; Copier, Jaël S; Vermij, Sarah H.; Li, Zhen; van der Nagel, Roel; Zhang, Mingliang; de Bakker, Jacques M T; Glass, Aaron M; Mohler, Peter J; Taffet, Steven M; Vos, Marc A; van Rijen, Harold V M; Delmar, Mario; van Veen, Toon A B (2019). Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress. International journal of molecular sciences, 20(17) Molecular Diversity Preservation International MDPI 10.3390/ijms20174076
Volume 20
Issue 17
Human variants in plakophilin-2 (PKP2) associate with most cases of familial arrhythmogenic cardiomyopathy (ACM). Recent studies show that PKP2 not only maintains intercellular coupling, but also regulates transcription of genes involved in Ca2+ cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612a305374d1d1c344284cc5084b43b4
https://pure.amc.nl/en/publications/plakophilin2-haploinsufficiency-causes-calcium-handling-deficits-and-modulates-the-cardiac-response-towards-stress(2519daf6-96ab-4286-8e3a-ce0c4826d452).html
https://pure.amc.nl/en/publications/plakophilin2-haploinsufficiency-causes-calcium-handling-deficits-and-modulates-the-cardiac-response-towards-stress(2519daf6-96ab-4286-8e3a-ce0c4826d452).html
Publikováno v:
Cellular and Molecular Life Sciences. 72:2899-2910
Connexin43 and pannexin1 are found in immune cells. While gap junctional communication has been demonstrated between immune cells, hemichannels have been implicated in many cellular functions. Among the functions involved as being connexin dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b696419345868534859fb083c64f2d5
https://doi.org/10.1007/s00018-015-1966-3
https://doi.org/10.1007/s00018-015-1966-3
Autor:
Steven M. Taffet, Mario Delmar, Anna Pfenniger, Lucile Miquerol, Marc Chanson, Rob Krams, Merlijn J. Meens, Jean-François Denis, Brenda R. Kwak, K. E. Ludwig Scheckenbach
Publikováno v:
Oncotarget, Vol. 8, No 31 (2017) pp. 50972-50986
Oncotarget
Oncotarget
// Jean-Francois Denis 1, * , K.E. Ludwig Scheckenbach 1, * , Anna Pfenniger 1, 2 , Merlijn J. Meens 1 , Rob Krams 3 , Lucile Miquerol 4 , Steven Taffet 5 , Marc Chanson 6 , Mario Delmar 7 and Brenda R. Kwak 1, 2 1 Department of Pathology and Immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3203dbd97ba104a1a20ba8f404f35d9
http://hdl.handle.net/10044/1/46085
http://hdl.handle.net/10044/1/46085
Autor:
Elizabeth Eill, Steven M Taffet
Publikováno v:
The Journal of Immunology. 202:58.19-58.19
In macrophages, the expression and regulation of the gap junction protein connexin43 (Cx43) is poorly understood. Here we demonstrate that inflammatory and anti-inflammatory mediators differentially regulate gap junction plaque formation in primary b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36874978c2c8e76d23f260cb7ecc6df
https://doi.org/10.4049/jimmunol.202.supp.58.19
https://doi.org/10.4049/jimmunol.202.supp.58.19
Publikováno v:
The Journal of Immunology. 190:4830-4835
Macrophages that lack connexin43 (Cx43), a gap junction protein, have been reported to exhibit dramatic deficiencies in phagocytosis. In this study, we revisit these findings using well-characterized macrophage populations. Cx43 knockout (Cx43−/−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b90dbde0ff9f8e859405613cf83ab8d
https://doi.org/10.4049/jimmunol.1202884
https://doi.org/10.4049/jimmunol.1202884
Autor:
Rob Krams, Mario Delmar, Steven M. Taffet, Anna Pfenniger, Ludwig Scheckenbach, Merlijn J. Meens, Jean-François Denis, Brenda R. Kwak, Marc Chanson, Lucile Miquerol
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 8(3)
Endothelial cells (ECs) of healthy arteries express high levels of connexin40 (Cx40), but this expression is lost in ECs overlying atherosclerotic plaques. Low/oscillatory shear stress observed in bends and bifurcations of arteries is known to be ath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887988209500b43d9015f0cac61385dd
Publikováno v:
Cell Communication & Adhesion. 18:73-84
During development, epicardial cells act as progenitors for a large fraction of non-myocyte cardiac cells. Expression and function of molecules of the desmosome in the postnatal epicardium has not been studied. The objective of this study was to asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedb1f3d91d97513a2838181ab22dc62
https://doi.org/10.3109/15419061.2011.621561
https://doi.org/10.3109/15419061.2011.621561
Autor:
Ferenc Puskas, Jérôme Kalifa, Omer Berenfeld, Kimberly Kasprowicz, Luna Bhatta, José Jalife, Michael F. Swartz, Steven M. Taffet, Charles J. Lutz, Gregory W. Fink, Karen L. Vikstrom
Publikováno v:
Heart Rhythm. 6:1415-1422
Background The development of atrial fibrillation (AF) after cardiac surgery is associated with adverse outcomes; however, the mechanism(s) that trigger and maintain AF in these patients are unknown. Objective The purpose of this study was to test ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0888cc64a66e5bf1e9842da702e9d22
https://doi.org/10.1016/j.hrthm.2009.06.018
https://doi.org/10.1016/j.hrthm.2009.06.018
Autor:
Lori L. Isom, Guadalupe Guerrero-Serna, Wanda Coombs, Mario Delmar, Hassan Hussein Musa, Priscila Y. Sato, Steven M. Taffet, Gustavo Patino
Publikováno v:
Circulation Research. 105:523-526
Rationale: Plakophilin-2 (PKP2) is an essential component of the cardiac desmosome. Recent data show that it interacts with other molecules of the intercalated disc. Separate studies show preferential localization of the voltage-gated sodium channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67416f8e6b11b9f3b31e70f00064cf10
https://doi.org/10.1161/circresaha.109.201418
https://doi.org/10.1161/circresaha.109.201418
Autor:
Steven M. Taffet, Thien D. Nguyen
Publikováno v:
Molecular Immunology. 46:2938-2946
Connexin 43 (Cx43) is the predominant gap junction protein expressed in immune cells. Previous manuscripts have stated that gap junctions may play a role in antigen cross-presentation, dendritic cell maturation, T cell development, and regulatory T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b1b0963b46aafaa758d838434c4147
https://doi.org/10.1016/j.molimm.2009.06.022
https://doi.org/10.1016/j.molimm.2009.06.022