Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Steven M Pogwizd"'
Autor:
Yujie Zhu, Mohamed A Hanafy, Cheryl R Killingsworth, Gregory P Walcott, Martin E Young, Steven M Pogwizd
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105379 (2014)
Patients with chronic heart failure (CHF) exhibit a morning surge in ventricular arrhythmias, but the underlying cause remains unknown. The aim of this study was to determine if heart rate dynamics, autonomic input (assessed by heart rate variability
Externí odkaz:
https://doaj.org/article/6d6ba88654d84dcbba71cb8162d92131
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93928 (2014)
Cardiac glycosides have been used for the treatment of heart failure because of their capabilities of inhibiting Na+/K+ ATPase (NKA), which raises [Na+]i and attenuates Ca2+ extrusion via the Na+/Ca2+ exchanger (NCX), causing [Ca2+]i elevation. The r
Externí odkaz:
https://doaj.org/article/5c397893bed343fca8e3d05d01d14d4c
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111411 (2014)
Cardioprotection in females, as observed in the setting of heart failure, has been attributed to sex differences in intracellular calcium handling and its modulation by β-adrenergic signaling. However, further studies examining sex differences in β
Externí odkaz:
https://doaj.org/article/f4fa6bc8480547c482c4e540c122e2ab
Autor:
Justin M. Quiles, Mark E. Pepin, Sini Sunny, Sandeep B. Shelar, Anil K. Challa, Brian Dalley, John R. Hoidal, Steven M. Pogwizd, Adam R. Wende, Namakkal S. Rajasekaran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Although recent advances in the treatment of acute coronary heart disease have reduced mortality rates, few therapeutic strategies exist to mitigate the progressive loss of cardiac function that manifests as heart failure. Nuclear factor, er
Externí odkaz:
https://doaj.org/article/0bacb871034845faa009f27435e581fe
Autor:
Jiajie Yan, Steven M. Pogwizd, Greg Walcott, Jian Huang, Cheryl R. Killingsworth, Yujie Zhu, Xun Ai, Silvio H. Litovsky
Publikováno v:
J Mol Cell Cardiol
Background Both gap junctional remodeling and interstitial fibrosis have been linked to impaired electrical conduction velocity (CV) and fatal ventricular arrhythmias in nonischemic heart failure (HF). However, the arrhythmogenic role of the ventricu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62328e0a00c221eacedf6ecfde1c52ce
https://doi.org/10.1016/j.yjmcc.2021.05.012
https://doi.org/10.1016/j.yjmcc.2021.05.012
Autor:
Sini Sunny, Namakkal S. Rajasekaran, Justin M. Quiles, Adam R. Wende, Sandeep B. Shelar, Steven M. Pogwizd, John R. Hoidal, Brian Dalley, Mark E Pepin, Anil K. Challa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Although recent advances in the treatment of acute coronary heart disease have reduced mortality rates, few therapeutic strategies exist to mitigate the progressive loss of cardiac function that manifests as heart failure. Nuclear factor, erythroid 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2a800252cdf9a1b96daebc480b9d68
https://doaj.org/article/0bacb871034845faa009f27435e581fe
https://doaj.org/article/0bacb871034845faa009f27435e581fe
Autor:
Selwyn M. Vickers, Mark E Pepin, Salpy V. Pamboukian, Joseph Barchue, Chae-Myeong Ha, Ayman Haj Asaad, Sayan Bakshi, Steven M. Pogwizd, Bertha Hidalgo, Adam R. Wende, Luke A Potter
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
Am J Physiol Heart Circ Physiol
Am J Physiol Heart Circ Physiol
Heart failure (HF) is a multifactorial syndrome that remains a leading cause of worldwide morbidity. Despite its high prevalence, only half of patients with HF respond to guideline-directed medical management, prompting therapeutic efforts to confron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e451096337a136760f14eccfb24b465f
http://europepmc.org/articles/PMC8163657
http://europepmc.org/articles/PMC8163657
Autor:
Weiwei Zhao, Xin Wu, Jin Qin, Xun Ai, Jiajie Yan, Steven M. Pogwizd, Aimee Wu, Mei Yang, Shengtao Yuan
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:351-362
Pathological remodeling includes alterations of ion channel function and calcium homeostasis and ultimately cardiac maladaptive function during the process of disease development. Biochemical assays are important approaches for assessing protein abun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b60005ecb7f03a809c5ad4c1359686
https://doi.org/10.1007/s00424-021-02538-x
https://doi.org/10.1007/s00424-021-02538-x
Publikováno v:
Echocardiography. 37:1080-1083
Reverse Takotsubo cardiomyopathy (rTTC) is a variant of Takotsubo cardiomyopathy (TTC) or stress-induced cardiomyopathy. TTC is a transient cardiomyopathy resulting in a heart failure syndrome, triggered by emotional and/or physical stressors, that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad2dff0c579d0587a994f8ac17c59cf
https://doi.org/10.1111/echo.14700
https://doi.org/10.1111/echo.14700
Autor:
Grace E. Salzer, Katherine A Margolies, Steven M. Pogwizd, Silvio H. Litovsky, Michelle Gray, Yujie Zhu, Isaac Shamblin, Lita M. Araysi, Efrain Rodriguez, Ganesh V. Halade, Sabine Huke
Publikováno v:
Hum Mol Genet
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease. There is accumulating evidence that HD patients have increased prevalence of conduction abnormalities and compromised sinoatrial node function which could lead to increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c6906f2a2c2c1819cb43b318f8bcc1
https://doi.org/10.1093/hmg/ddz295
https://doi.org/10.1093/hmg/ddz295