Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Steven M Moss"'
Autor:
David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser
Publikováno v:
eLife, Vol 5 (2016)
Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance
Externí odkaz:
https://doaj.org/article/f3e8373dbc7b4012a1c82425c9fb49fb
Autor:
Horace Wong, Corinne Moss, Steven M. Moss, Vibhuti Shah, Scott A. Halperin, Shinya Ito, Priyanjali Mithal, Angie Qu, Anna Taddio
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 4, Pp 995-1002 (2019)
Objectives: Recommendations regarding the need to use alcohol prior to vaccine injections are inconsistent and based on low-level evidence. The objective was to assess the effectiveness of alcohol in reducing local skin reactions and infection post-v
Externí odkaz:
https://doaj.org/article/ac3415a7d67447e9b45dc0ccabafbd80
Autor:
Jaya Sangodkar, Nevan J. Krogan, Myung Chang Lee, Julia Arand, Janos Demeter, Christina S. Kong, Yeonjoo C. Hwang, Michael Ohlmeyer, Rebecca S. Levin, Julie H. Ko, Kevan M. Shokat, Garry L. Coles, John D. Gordan, James T. Webber, Julien Sage, Peter K. Jackson, Brandon Mauch, Steven M. Moss, Yan Ting Shue, Danielle L. Swaney, Nancie Mooney, Vicky Le, Sandra Cristea, Jessica N. Spradlin, Daniel K. Nomura, Goutham Narla, Andy He, Alexandros P. Drainas
Publikováno v:
Cancer cell, vol 38, iss 1
Cancer Cell
Cancer Cell
Summary Using unbiased kinase profiling, we identified protein kinase A (PKA) as an active kinase in small cell lung cancer (SCLC). Inhibition of PKA activity genetically, or pharmacologically by activation of the PP2A phosphatase, suppresses SCLC ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dee69fb505c4d4c08908c08dfb21b63
https://escholarship.org/uc/item/5rk5q37z
https://escholarship.org/uc/item/5rk5q37z
Autor:
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Board on Life Sciences, Frances Sharples, Andrew Bremer, Steven M. Moss, Anne Frances Johnson
Quantum concepts hold the potential to enable significant advances in sensing and imaging technologies that could be vital to the study of biological systems. The workshop Quantum Science Concepts in Enhancing Sensing and Imaging Technologies: Applic
Autor:
Isabelle R. Taylor, Steven M. Moss, Shaeri Mukherjee, Davide Ruggero, Jason E. Gestwicki, Kevan M. Shokat
Publikováno v:
Cell host & microbe, vol 25, iss 3
Summary Legionella pneumophila (L.p.), the microbe responsible for Legionnaires’ disease, secretes ∼300 bacterial proteins into the host cell cytosol. A subset of these proteins affects a wide range of post-translational modifications (PTMs) to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea4d54f70f4792c0d8ec9084040c359
https://europepmc.org/articles/PMC6529236/
https://europepmc.org/articles/PMC6529236/
Autor:
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Board on Life Sciences, Frances Sharples, Steven M. Moss, Robert Pool
One of the holy grails in biology is the ability to predict functional characteristics from an organism's genetic sequence. Despite decades of research since the first sequencing of an organism in 1995, scientists still do not understand exactly how
Publikováno v:
Sustainability, Vol 13, Iss 1627, p 1627 (2021)
Sustainability
Volume 13
Issue 4
Sustainability
Volume 13
Issue 4
This article provides an overview of the U.S. bioeconomy, discussing how its definition has evolved and been formalized over time. The first attempts to conceptualize and define the U.S. bioeconomy began in the early 1990s. This was followed by a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d11cb9c01795a28e184ce1817aacd78
https://doi.org/10.3390/su13041627
https://doi.org/10.3390/su13041627
Autor:
Braden D. Siempelkamp, Manoj K. Rathinaswamy, John E. Burke, Meredith L. Jenkins, Kevan M. Shokat, Daniel Gentile, Adam R. Renslo, Steven M. Moss
Publikováno v:
Cell chemical biology, vol 24, iss 12
Summary Covalent inhibitors of K-Ras(G12C) have been reported that exclusively recognize the GDP state. Here, we utilize disulfide tethering of a non-natural cysteine (K-Ras(M72C)) to identify a new switch-II pocket (S-IIP) binding ligand (2C07) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6faf562060556e02d0bf8c6bdeb2b9
https://escholarship.org/uc/item/2jm22087
https://escholarship.org/uc/item/2jm22087
Autor:
Charles S. Craik, Nicole O. Meyer, Ursula Schulze-Gahmen, Michael B. Winter, Steven M. Moss, Giselle M. Knudsen, Anthony J. O’Donoghue, Matthew Ravalin
Publikováno v:
Meyer, NO; O'Donoghue, AJ; Schulze-Gahmen, U; Ravalin, M; Moss, SM; Winter, MB; et al.(2017). Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs. ANALYTICAL CHEMISTRY, 89(8), 4550-4558. doi: 10.1021/acs.analchem.6b05002. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0tw726zx
Analytical chemistry, vol 89, iss 8
Analytical chemistry, vol 89, iss 8
The more than 500 protein kinases comprising the human kinome catalyze hundreds of thousands of phosphorylation events to regulate a diversity of cellular functions; however, the extended substrate specificity is still unknown for many of these kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0985919208e3ad6207bfbcc4c7e98c6
http://www.escholarship.org/uc/item/0tw726zx
http://www.escholarship.org/uc/item/0tw726zx