Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Steven M Colegate"'
Publikováno v:
Chemical research in toxicology. 35(3)
Sporadic motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), can be caused by spontaneous genetic mutations. However, many sporadic cases of ALS and other debilitating neurodegenerative diseases (NDDs) are believed to be caused
Publikováno v:
Toxicon. 167:60-66
Wild parsnip (Pastinaca sativa) has been associated with livestock and human photosensitization. An investigation of a natural occurrence of photosensitization of grazing horses identified wild parsnip as a possible cause. HPLC-MS and MS/MS analysis
Autor:
Thomas Hofmann, Russell J. Molyneux, John A. Edgar, Laura L. McConnell, Peter Schieberle, Steven M. Colegate, John J. Beck, John Gilbert, William Gaffield
Publikováno v:
Pure and Applied Chemistry. 91:1417-1437
Isolation of endogenous constituents of foods is generally performed in order to elucidate the biological activity of individual compounds and their role with respect to factors such as organoleptic qualities, health and nutritional benefits, plant p
Publikováno v:
Toxins, Vol 8, Iss 12, p 356 (2016)
Dehydropyrrolizidine alkaloid (DHPA)-producing plants have a worldwide distribution amongst flowering plants and commonly cause poisoning of livestock, wildlife, and humans. Previous work has produced considerable understanding of DHPA metabolism, to
Externí odkaz:
https://doaj.org/article/68bc8dffcc7d43bc9e1169ebd1a68c06
Publikováno v:
Journal of agricultural and food chemistry. 68(22)
Publikováno v:
Phytochemical Analysis. 29:613-626
Introduction Pro-toxic dehydropyrrolizidine alkaloids are associated with liver disease in humans. The potential for long-term, low-level or intermittent exposures to cause or contribute to chronically-developing diseases is of international concern.
Autor:
Dale R. Gardner, Steven M. Colegate, Ottmar W. Fischer, Michael Boppré, Sigrid Liede-Schumann, Joseph M. Betz
Publikováno v:
Phytochemical Analysis. 27:257-276
INTRODUCTION: Within the Apocynoideae (Apocynaceae) pro‐toxic dehydropyrrolizidine alkaloids have been reported only in Echiteae. However, attraction of pyrrolizidine alkaloid‐pharmacophagous insects suggested their presence in Alafia cf. caudata
Publikováno v:
Innovation at the NHP/Food Interface.
Publikováno v:
Journal of Ethnopharmacology. 172:179-194
Ethnopharmacological relevance Asmachilca is a Peruvian medicinal herb preparation ostensibly derived from Aristeguietia gayana (Wedd.) R.M. King & H. Rob. (Asteraceae: Eupatorieae). Decoctions of the plant have a reported bronchodilation effect that
Publikováno v:
Toxicon. 97:36-45
Plants producing dehydropyrrolizidine alkaloids (DHPAs) are found throughout the world and they are dangerous to human and animal health. Several DHPAs are carcinogenic but only riddelliine has been classified as a potential human carcinogen by the N