Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Steven M Colegate"'
Publikováno v:
Chemical research in toxicology. 35(3)
Sporadic motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), can be caused by spontaneous genetic mutations. However, many sporadic cases of ALS and other debilitating neurodegenerative diseases (NDDs) are believed to be caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374b1d9f6035c7008c9a95e28e490ce3
https://pubmed.ncbi.nlm.nih.gov/35238548
https://pubmed.ncbi.nlm.nih.gov/35238548
Publikováno v:
Toxicon. 167:60-66
Wild parsnip (Pastinaca sativa) has been associated with livestock and human photosensitization. An investigation of a natural occurrence of photosensitization of grazing horses identified wild parsnip as a possible cause. HPLC-MS and MS/MS analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3e9e0c0b04a77653f9fe60c93781e5
https://doi.org/10.1016/j.toxicon.2019.06.007
https://doi.org/10.1016/j.toxicon.2019.06.007
Autor:
Thomas Hofmann, Russell J. Molyneux, John A. Edgar, Laura L. McConnell, Peter Schieberle, Steven M. Colegate, John J. Beck, John Gilbert, William Gaffield
Publikováno v:
Pure and Applied Chemistry. 91:1417-1437
Isolation of endogenous constituents of foods is generally performed in order to elucidate the biological activity of individual compounds and their role with respect to factors such as organoleptic qualities, health and nutritional benefits, plant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5a6b4c1802be7f72411f4b03c41c89
https://doi.org/10.1515/pac-2017-1204
https://doi.org/10.1515/pac-2017-1204
Publikováno v:
Toxins, Vol 8, Iss 12, p 356 (2016)
Dehydropyrrolizidine alkaloid (DHPA)-producing plants have a worldwide distribution amongst flowering plants and commonly cause poisoning of livestock, wildlife, and humans. Previous work has produced considerable understanding of DHPA metabolism, to
Externí odkaz:
https://doaj.org/article/68bc8dffcc7d43bc9e1169ebd1a68c06
Publikováno v:
Journal of agricultural and food chemistry. 68(22)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb6813892620e0e8f53b13af1c693ed
https://pubmed.ncbi.nlm.nih.gov/32432873
https://pubmed.ncbi.nlm.nih.gov/32432873
Publikováno v:
Phytochemical Analysis. 29:613-626
Introduction Pro-toxic dehydropyrrolizidine alkaloids are associated with liver disease in humans. The potential for long-term, low-level or intermittent exposures to cause or contribute to chronically-developing diseases is of international concern.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f767913471a33f89a4e318ece3c736
https://doi.org/10.1002/pca.2775
https://doi.org/10.1002/pca.2775
Autor:
Dale R. Gardner, Steven M. Colegate, Ottmar W. Fischer, Michael Boppré, Sigrid Liede-Schumann, Joseph M. Betz
Publikováno v:
Phytochemical Analysis. 27:257-276
INTRODUCTION: Within the Apocynoideae (Apocynaceae) pro‐toxic dehydropyrrolizidine alkaloids have been reported only in Echiteae. However, attraction of pyrrolizidine alkaloid‐pharmacophagous insects suggested their presence in Alafia cf. caudata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c28c5b64a4a691add6a29249aa8287f
https://doi.org/10.1002/pca.2624
https://doi.org/10.1002/pca.2624
Publikováno v:
Innovation at the NHP/Food Interface.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18eb5ecc0d9a470d8abbd9af78bb5c82
https://doi.org/10.1055/s-0038-1644957
https://doi.org/10.1055/s-0038-1644957
Publikováno v:
Journal of Ethnopharmacology. 172:179-194
Ethnopharmacological relevance Asmachilca is a Peruvian medicinal herb preparation ostensibly derived from Aristeguietia gayana (Wedd.) R.M. King & H. Rob. (Asteraceae: Eupatorieae). Decoctions of the plant have a reported bronchodilation effect that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d2c0a8a85137ac7b9b53cb77f03f75
https://doi.org/10.1016/j.jep.2015.06.012
https://doi.org/10.1016/j.jep.2015.06.012
Publikováno v:
Toxicon. 97:36-45
Plants producing dehydropyrrolizidine alkaloids (DHPAs) are found throughout the world and they are dangerous to human and animal health. Several DHPAs are carcinogenic but only riddelliine has been classified as a potential human carcinogen by the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec5fca9989217494bb01b0f959c4b97
https://doi.org/10.1016/j.toxicon.2015.02.001
https://doi.org/10.1016/j.toxicon.2015.02.001