Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Steven M Chamow"'
Autor:
Rena A. Mizrahi, Wendy Y. Lin, Ashley Gras, Ariel R. Niedecken, Ellen K. Wagner, Sheila M. Keating, Nikita Ikon, Vishal A. Manickam, Michael A. Asensio, Jackson Leong, Angelica V. Medina-Cucurella, Emily Benzie, Kyle P. Carter, Yao Chiang, Robert C. Edgar, Renee Leong, Yoong Wearn Lim, Jan Fredrik Simons, Matthew J. Spindler, Kacy Stadtmiller, Nicholas Wayham, Dirk Büscher, Jose Vicente Terencio, Clara Di Germanio, Steven M. Chamow, Charles Olson, Paula A. Pino, Jun-Gyu Park, Amberlee Hicks, Chengjin Ye, Andreu Garcia-Vilanova, Luis Martinez-Sobrido, Jordi B. Torrelles, David S. Johnson, Adam S. Adler
Publikováno v:
Pathogens, Vol 11, Iss 7, p 806 (2022)
Conventionally, hyperimmune globulin drugs manufactured from pooled immunoglobulins from vaccinated or convalescent donors have been used in treating infections where no treatment is available. This is especially important where multi-epitope neutral
Externí odkaz:
https://doaj.org/article/30fbcf61da8b46ddab93ba7e247ee57f
Autor:
Christine V.F. Carrington, Steven M Chamow, Adam S. Adler, Matthew Adams, Sheila M. Keating, Emma Pearce, Ashley Gras, Robert C. Edgar, Charles Olson, Dirk Büscher, Jasmeen Saini, Kyle P Carter, Ariel R Niedecken, Heather E. Lynch, Rachel Mosher, Ellen K. Wagner, Vishal A. Manickam, Renee Leong, Bishal K. Gautam, Jan Fredrik Simons, Marcus O. Muench, Matthew J. Spindler, Jose Vicente Terencio, LaRee Tracy, Brendan Tinsley, Thomas H. Oguin, David S. Johnson, Yao Chiang, Nicholas Wayham, Everett Meyer, Rena A. Mizrahi, Anushka T. Ramjag, Carl A. Ross, Carina Vingsbo Lundberg, David Goldblatt, Matthew J Walch, Yoong Wearn Lim, Jackson Leong, Michael A. Asensio, Lucy Roalfe, Robert Jeanfreau, Emily Benzie, Christopher R. Bartley, Graham Simmons, Hayley Richardson, Bryan Monroe, Angélica V Medina-Cucurella, Kacy Stadtmiller
Publikováno v:
Nature biotechnology
Plasma-derived polyclonal antibody therapeutics, such as intravenous immunoglobulin, have multiple drawbacks, including low potency, impurities, insufficient supply, and batch-to-batch variation. Here we describe a microfluidics and molecular genomic
Autor:
David G. Gorenstein, Cynthia W. Tuthill, Steven M. Chamow, David E. Volk, Miguel-Angel Elizondo-Riojas
Publikováno v:
Biochemical and Biophysical Research Communications. 416:356-361
800 MHz NMR structure of the 28-residue peptide thymosin alpha-1 in 40% TFE/60% water (v/v) has been determined. Restrained molecular dynamic simulations with an explicit solvent box containing 40% TFE/60% TIP3P water (v/v) were used, in order to get
Edited by three pioneers in the field, each with longstanding experience in the biotech industry, and a skilled scientific writer, this is the first book to cover every step in the development and production of immunoglobulin Fc-fusion proteins as th
Autor:
Helen E Chadd, Steven M Chamow
Publikováno v:
Current Opinion in Biotechnology. 12:188-194
With the technological advances made during the past decade, antibodies now represent an important and growing class of biotherapeutics. With the potential new targets resulting from genomics and with methods now in place to make fully human antibodi
Publikováno v:
Therapeutic Fc-Fusion Proteins
Therapeutic Fc fusion proteins , Therapeutic Fc fusion proteins , کتابخانه مرکزی دانشگاه علوم پزشکی تهران
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b31c8ab11e775199cd4c210d5cd82edd
https://doi.org/10.1002/9783527675272
https://doi.org/10.1002/9783527675272
Autor:
Dave Brousseau, Judith A. Fox, Adriana Johnson, David H. Peers, Phillip W. Berman, Thomas Ryll, Sabrina Tom, Timothy A. Hotaling, Richard L. Gehant, Steven M. Chamow, Christiane Köhne
Publikováno v:
Journal of Cellular Biochemistry. 75:446-461
Strategies that prevent the attachment of N-linked carbohydrates to nascent glycoproteins often impair intracellular transport and secretion. In the present study, we describe a method to rescue the intracellular transport and secretion of glycoprote
Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins
Autor:
Lynne A. Krummen, David H. Peers, K. Carroll, S. Mehta, Damon I. Papac, Vanessa Chisholm, Nishit B. Modi, Martin Gawlitzek, S. Weikert, S. Tom, Steven M. Chamow, Phillip W. Berman, D. Cowfer, J. Briggs, J. Lofgren, S. Eppler
Publikováno v:
Nature Biotechnology. 17:1116-1121
We have engineered two Chinese hamster ovary cell lines secreting different recombinant glycoproteins to express high levels of human beta1,4-galactosyltransferase (GT, E.C. 2.4.1.38) and/or alpha2, 3-sialyltransferase (ST, E.C. 2.4.99.6). N-linked o
Publikováno v:
Biotechnology and Bioengineering. 62:208-215
To extend the feasibility of chromatofocusing to industrial use, we have developed a simple chromatofocusing buffer system capable of generating a smooth pH gradient without the use of an external gradient maker. Using two cationic buffering componen