Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Steven M, Trothen"'
Autor:
Steven M. Trothen, Jack E. Teplitsky, Ryan E. Armstong, Rong Xuan Zang, Antony Lurie, Mitchell J. Mumby, Cassandra R. Edgar, Matthew W. Grol, Jimmy D. Dikeakos
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 35014-35027 (2024)
Externí odkaz:
https://doaj.org/article/8db81e63a0864d3d810cfdfc063a61a1
Publikováno v:
FEBS Letters. 596:232-248
Phosphofurin acidic cluster sorting protein 1 (PACS-1) is canonically a cytosolic trafficking protein, yet recent reports have described nuclear roles for PACS-1. Herein, we sought to define the nuclear transport mechanism of PACS-1. We demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d0b8dbf4fac38e76950495bdfbca27
https://doi.org/10.1002/1873-3468.14243
https://doi.org/10.1002/1873-3468.14243
Autor:
Jimmy D. Dikeakos, Cassandra R Edgar, Andrés Finzi, S. M. Mansour Haeryfar, Alexa Galbraith, Jérémie Prévost, Mitchell J. Mumby, Rajesh Abraham Jacob, Frank Kirchhoff, Antony Lurie, Steven M. Trothen
Publikováno v:
The Journal of Biological Chemistry
Prolonged immune activation drives the upregulation of multiple checkpoint receptors on the surface of virus-specific T cells, inducing their exhaustion. Reversing HIV-1-induced T cell exhaustion is imperative for efficient virus clearance; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4498fbba12fc0bc9e4265261297f405
http://europepmc.org/articles/PMC8390549
http://europepmc.org/articles/PMC8390549
Autor:
Cassandra R Edgar, Jimmy D. Dikeakos, Steven M. Trothen, Aaron L. Johnson, Eric J. Arts, Mitchell J. Mumby, Peter B. Stathopulos, Richard M. Gibson
Publikováno v:
J Virol
Serine incorporator 5 (SERINC5) reduces the infectivity of progeny HIV-1 virions by incorporating into the outer host-derived viral membrane during egress. To counter SERINC5, the HIV-1 accessory protein Nef triggers SERINC5 internalization by engagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d88411f5351c4a5bb5b869a384350b
https://doi.org/10.1128/jvi.00588-21
https://doi.org/10.1128/jvi.00588-21
Autor:
Ronald S. Flannagan, Tayler J. Farrell, Steven M. Trothen, Jimmy D. Dikeakos, David E. Heinrichs
Publikováno v:
Blood Adv
Nutrient sequestration is an essential facet of host innate immunity. Macrophages play a critical role in controlling iron availability through expression of the iron transport protein ferroportin (FPN), which extrudes iron from the cytoplasm to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fc74a37f154b499215074b9eabaa21
https://pubmed.ncbi.nlm.nih.gov/33496744
https://pubmed.ncbi.nlm.nih.gov/33496744
Autor:
Jérémie, Prévost, Cassandra R, Edgar, Jonathan, Richard, Steven M, Trothen, Rajesh Abraham, Jacob, Mitchell J, Mumby, Suzanne, Pickering, Mathieu, Dubé, Daniel E, Kaufmann, Frank, Kirchhoff, Stuart J D, Neil, Andrés, Finzi, Jimmy D, Dikeakos
Publikováno v:
J Virol
Along with other immune checkpoints, T cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is expressed on exhausted CD4(+) and CD8(+) T cells and is upregulated on the surface of these cells upon infection by human immunodeficiency vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb4127e9bcd01575c262d0b41ed249eb
https://pubmed.ncbi.nlm.nih.gov/31941771
https://pubmed.ncbi.nlm.nih.gov/31941771