Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Steven L. Baldwin"'
Autor:
Gregory M. Lanza, John E. Heuser, Grace Hu, Steven L Baldwin, Jon N. Marsh, Jeffrey M. Arbeit, Neeleesh R Soman, Samuel A. Wickline, Paul H. Schlesinger
Publikováno v:
Journal of Clinical Investigation. 119:2830-2842
The in vivo application of cytolytic peptides for cancer therapeutics is hampered by toxicity, nonspecificity, and degradation. We previously developed a specific strategy to synthesize a nanoscale delivery vehicle for cytolytic peptides by incorpora
Autor:
James G. Miller, Min Yang, Steven L. Baldwin, Karen R. Marutyan, Mark R. Holland, Kirk D. Wallace
Publikováno v:
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. 54:1360-1369
Increased myocardial stiffness in aging and diabetes that may result in pathologies such as diastolic dysfunction has been attributed, in part, to an increase in cross linking of extracellular matrix proteins such as collagen. With the development of
Autor:
James G. Miller, Mark R. Holland, Kirk D. Wallace, Steven L. Baldwin, Min Yang, Karen R. Marutyan
Publikováno v:
The Journal of the Acoustical Society of America. 119:3130-3139
Echocardiography requires imaging of the heart with sound propagating at varying angles relative to the predominant direction of the myofibers. The degree of anisotropy of attenuation can significantly influence ultrasonic imaging and tissue characte
Autor:
James G. Miller, Mark R. Holland, Kirk D. Wallace, Min Yang, Karen R. Marutyan, Steven L. Baldwin
Publikováno v:
Ultrasound in Medicine & Biology. 32:603-610
The objectives of this study were to measure the frequency dependence of the ultrasonic velocity in myocardium and to quantify the frequency dependence of phase velocity as a function of the insonification angle relative to the predominant direction
Publikováno v:
Medical Physics. 32:418-426
Measurements of tissue properties using an image-based technique that makes use of an external reference may have the potential for practical clinical implementation in echocardiography. The objective of this study was to quantify the ability of this
Publikováno v:
Journal of the American Society of Echocardiography. 14:782-788
Promising technical developments suggest that it may be feasible to use contrast echocardiography to estimate regional myocardial perfusion. Although the optimal approach has not yet been determined, the use of a nonlinear (harmonic) response of the
Publikováno v:
2008 IEEE Ultrasonics Symposium.
Background and Objective: Augmentation of local drug delivery from targeted nanoparticles (NP) with nondestructive, noncavitational clinical ultrasound (US) offers the potential to enhance therapeutic efficacy in diseases such as cancer while limitin
Autor:
Steven L. Baldwin, Kirk D. Wallace, Richard M. Keeling, Jon N. Marsh, Anne M. Connolly, Gregory M. Lanza, S.A. Wickline, Michael S. Hughes
Publikováno v:
IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 54(11)
Duchenne muscular dystrophy is a severe wasting disease, involving replacement of necrotic muscle tissue by fibrous material and fatty infiltrates. One primary animal model of this human disease is the X chromosome-linked mdx strain of mice. The goal
Autor:
Jeffrey M. Arbeit, Steven L. Baldwin, Jon N. Marsh, Michael S. Hughes, D. R. Znidersic, Robert Neumann, Kirk D. Wallace, John E. McCarthy, Gregory M. Lanza, Ralph W. Fuhrhop, B. N. Maurizi, S.A. Wickline
Publikováno v:
The Journal of the Acoustical Society of America. 121(6)
Qualitative and quantitative properties of the finite part, H(f), of the Shannon entropy of a continuous waveform f(t) in the continuum limit are derived in order to illuminate its use for waveform characterization. Simple upper and lower bounds on H
Autor:
Mark R. Holland, Kirk D. Wallace, Karen R. Marutyan, Steven L. Baldwin, Min Yang, James G. Miller
Publikováno v:
The Journal of the Acoustical Society of America. 119(3)
The goal of this study was to measure elastic stiffness coefficients of freshly excised and subsequently formalin-fixed myocardial tissue. Our approach was to measure the angle-dependent phase velocities associated with the propagation of a longitudi