Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Steven Kupczak"'
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
MycERT2 expression in pancreata of Mpdx1 and Mp48 mice is at a level comparable to that of endogenous c-Myc in proliferating neonatal pancreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1369634b3e6aac2bd088a54e80c2cf07
https://doi.org/10.1158/2159-8290.22535044.v1
https://doi.org/10.1158/2159-8290.22535044.v1
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Inhibition of the GAS6/AXL pathway selectively blocks a subset of Myc-induced stromal changes in KMp48 pancreatic tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511dd49d35671a97e38ff109d49c3462
https://doi.org/10.1158/2159-8290.22535026
https://doi.org/10.1158/2159-8290.22535026
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Myc instructs immediate onset of transition to pancreatic adenocarcinoma in KMpdx1 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b11d4cae0fec6948995f1c82793c8b
https://doi.org/10.1158/2159-8290.22535029
https://doi.org/10.1158/2159-8290.22535029
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Myc activation reversibly induces acinar-to-ductal metaplasia (ADM) in KMp48 pancreata in vivo and in isolated KMpdx1 pancreas cancer cells in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dafdbecd86817412ab02d807f59e65a
https://doi.org/10.1158/2159-8290.22535041
https://doi.org/10.1158/2159-8290.22535041
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
The signature features of pancreatic ductal adenocarcinoma (PDAC) are its fibroinflammatory stroma, poor immune activity, and dismal prognosis. We show that acute activation of Myc in indolent pancreatic intraepithelial neoplasm (PanIN) epithelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fb096b64ace5de33f588472ef8dc731
https://doi.org/10.1158/2159-8290.c.6547741.v1
https://doi.org/10.1158/2159-8290.c.6547741.v1
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Myc drives progression from PanIN to pancreatic adenocarcinoma in KMp48 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06222e4004742cd8733eb4c5f78323cf
https://doi.org/10.1158/2159-8290.22535035.v1
https://doi.org/10.1158/2159-8290.22535035.v1
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Histopathological progression of pancreatic tumors in KMp48 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1131222c96224e3917e12b1292effe97
https://doi.org/10.1158/2159-8290.22535032
https://doi.org/10.1158/2159-8290.22535032
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Myc de-activation triggers immediate onset of reversal of KMpdx1 tumor stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f2d5f190a2c5c782032683b3d5a102
https://doi.org/10.1158/2159-8290.22535014.v1
https://doi.org/10.1158/2159-8290.22535014.v1
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
PD-L1 blockade abrogates Myc-induced T cell exclusion from KMp48 tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4213e0087ecfa895636890c3a5ed19b3
https://doi.org/10.1158/2159-8290.22535023
https://doi.org/10.1158/2159-8290.22535023
Autor:
Gerard I. Evan, Trevor D. Littlewood, Mark J. Arends, Laura Soucek, Lamorna Brown Swigart, Panayiotis Anastasiou, Steven Kupczak, Luca Pellegrinet, Tania Campos, Valentin J.A. Barthet, Roderik M. Kortlever, Nicole M. Sodir
Comparison of Myc-induced stromal phenotypes in KRasG12D-driven PanIN versus KRasG12D-driven lung adenoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2fea709b5d1ce5d40e1e10d17aaebe
https://doi.org/10.1158/2159-8290.22535011
https://doi.org/10.1158/2159-8290.22535011