Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Steven K. Wolk"'
Autor:
Larry Gold, Nebojsa Janjic, Edward N. Brody, Guillot Jessica, Steven K. Wolk, David P. Astling, Wesley S. Mayfield, Amy D. Gelinas
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
The modern version of the RNA World Hypothesis begins with activated ribonucleotides condensing (nonenzymatically) to make RNA molecules, some of which possess (perhaps slight) catalytic activity. We propose that noncanonical ribonucleotides, which w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f021658d0f6db386f0081e09dbe83f1
https://doi.org/10.1073/pnas.1809041117
https://doi.org/10.1073/pnas.1809041117
Autor:
John C. Rohloff, Tomoki Suzuki, Fowler Catherine, Matthew R Otis, Sheela Waugh, Jeffery D Carter, Wesley S. Mayfield, Steven K. Wolk, Masao Hirota, Shashi Kumar Gupta, Daniel Schneider, Yuichi Ishikawa, Daniel W. Drolet, Nebojsa Janjic
Publikováno v:
Nucleic Acid Therapeutics
The addition of novel side chains at the 5-position of uracil is an effective means to increase chemical diversity of aptamers and hence the success rate for discovery of high-affinity ligands to protein targets. Such modifications also increase nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e2da3e232b3654d056563963fb036b
https://doi.org/10.1089/nat.2017.0683
https://doi.org/10.1089/nat.2017.0683
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Publikováno v:
Nucleic Acids Research
We have recently shown that the incorporation of modified nucleotides such as 5-N-carboxamide-deoxyuridines into random nucleic acid libraries improves success rates in SELEX experiments and facilitates the identification of ligands with slow off-rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffe34a15d27dc57cc897dee8e9909fe
https://pubmed.ncbi.nlm.nih.gov/26438535
https://pubmed.ncbi.nlm.nih.gov/26438535
Autor:
K. M. Yocom, Graham Swift, Ethan Scott Simon, Michael Bennett Freeman, Steven K. Wolk, Yi Hyon Paik
Publikováno v:
Macromolecular Symposia. 123:195-207
This paper outlines the requirements for truly acceptable biodegradable water-soluble polymers, in effect establishing the goals of a polymer synthesis program. The deficiencies of the current products are thus clearly identified. A brief review of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3591c412103ee36ef4c6bdcb7d56c1f
https://doi.org/10.1002/masy.19971230120
https://doi.org/10.1002/masy.19971230120
Autor:
Joseph A. Akkara, Steven K. Wolk, Graham Swift, Richard A. Gross, David L. Kaplan, Renee T. MacDonald, Yuri Y. Svirkin, Satish K. Pulapura
Publikováno v:
Macromolecules. 28:73-78
The polymerization of e-caprolactone, (e-CL) using porcine pancreatic lipase (PPL) as the catalyst was studied. Polymerization reactions (4 days, 65°C) of e-CL at ∼10% (w/v) concentrations in dioxane, toluene, and heptane using butanol as an initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1cd5a9984c58ef1c1cd0f8a7c368fe
https://doi.org/10.1021/ma00105a008
https://doi.org/10.1021/ma00105a008
Autor:
Yi Hyon Paik, Rebecca L. Smith, Steven K. Wolk, Graham Swift, Ethan Scott Simon, Kathryn M. Yocom
Publikováno v:
Macromolecules. 27:7613-7620
It is well-known that thermal treatment of aspartic acid produces poly(anhydroaspartic acid) (polysuccinimide), which can then be hydrolyzed to sodium polyaspartate. Both polysuccinimide and sodium polyaspartate have been analyzed by a variety of one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b46da167ac1bf95da4a498d77d09a923
https://doi.org/10.1021/ma00104a016
https://doi.org/10.1021/ma00104a016
Publikováno v:
Macromolecules. 27:6358-6362
Pseudomonas oleovorans was grown on 2-methyl-3-hydroryoctane, ethyl 2-methyl-3-hydroxyoctanoate, ammonium 2-methyl-3-hydroryoctanoate, and methyl 2-methyl-3-hydroryoctanoate in attempts to obtain poly(3-hydroxyalkanoate)s (PHAs), with methyl branches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b6be1ccd479fb7a96e366aebbf93f22
https://doi.org/10.1021/ma00100a019
https://doi.org/10.1021/ma00100a019
Autor:
Eric Eisenhart, Steven K. Wolk
Publikováno v:
Macromolecules. 26:1086-1090
Solution-state deuterium NMR experiments indicate that only about 30% of a partially deuterated allylmethacrylate (ALMA-d 5 ), a divinyl cross-linking agent, actually cross-linked in certain control polymers. In addition, these experiments provided i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f8ee00c4b745d259628cf88fa71bf5
https://doi.org/10.1021/ma00057a032
https://doi.org/10.1021/ma00057a032
Autor:
Steven K. Wolk, Tirthankar Ghosh
Publikováno v:
ChemInform. 25
We have investigated the reaction of HCl with 2methylisothiazol-3-one (1). In the presence of HCl, at elevated temperatures, (1) exists in equilibrium with the ring opened sulfenyl chloride (4). The existence of (4) has been proven by trapping with n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9399590ccfb923561a95a66fd189e569
https://doi.org/10.1002/chin.199436105
https://doi.org/10.1002/chin.199436105