Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Steven K Backues"'
Autor:
Mitchell D. Meyer, Jasmine Winzeler, Sophia M. Taylor, Alex Kilgore, Kimberly Edicha, Chase Chitwood, Zachary Spearin, S. K. Nadia Rahman Silvia, Ronith Chakraborty, Jesse E. Smith, Bridget Kennedy, Carson Zois, Hayley Cawthon, Mukiri Gilruth, Steven K. Backues
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Selective autophagy is a conserved subcellular process that maintains the health of eukaryotic cells by targeting damaged or toxic cytoplasmic components to the vacuole/lysosome for degradation. A key player in the initiation of selective autophagy i
Externí odkaz:
https://doaj.org/article/0482a24a4e884bb3a4308bb53a8e73d8
Publikováno v:
The FASEB Journal. 36
Autor:
Steven K. Backues, Daniel J. Klionsky
Publikováno v:
Neuromethods ISBN: 9781071615881
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f755ca9778e52f647dc85798c67a22
https://doi.org/10.1007/978-1-0716-1589-8_1
https://doi.org/10.1007/978-1-0716-1589-8_1
Autor:
John M Smith, Michelle E Leslie, Samuel J Robinson, David A Korasick, Tong Zhang, Steven K Backues, Peter V Cornish, Abraham J Koo, Sebastian Y Bednarek, Antje Heese
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004578 (2014)
Vesicular trafficking has emerged as an important means by which eukaryotes modulate responses to microbial pathogens, likely by contributing to the correct localization and levels of host components necessary for effective immunity. However, conside
Externí odkaz:
https://doaj.org/article/eaa654f776a847babd118223eff1d8af
Publikováno v:
Biochemical and Biophysical Research Communications. 503:651-656
The induction of bulk autophagy by nitrogen starvation in baker's yeast (S. cerevisiae) involves the upregulation of many autophagy related proteins, including Atg7. One way to investigate the importance of this upregulation is to measure the size an
Autor:
Jens Füllgrabe, Steven K. Backues, Bertrand Joseph, Patricia González-Rodríguez, Meiyan Jin, Amélie Bernard, Elizabeth Delorme-Axford, Daniel J. Klionsky
Publikováno v:
Current Biology. 25:546-555
Summary Background Autophagy is a conserved process mediating vacuolar degradation and recycling. Autophagy is highly upregulated upon various stresses and is essential for cell survival in deleterious conditions. Autophagy defects are associated wit
Autor:
Yang Cao, Kushal Singh, Steven K. Backues, Amélie Bernard, Daniel P. Orban, Daniel J. Klionsky
Publikováno v:
Traffic. 16:172-190
Atg9 is a conserved multipass transmembrane protein with an essential role in autophagy. In Saccharomyces cerevisiae, it travels through the secretory pathway to a unique compartment, the Atg9 peripheral structures. These structures are then targeted
Publikováno v:
Autophagy. 12(4)
Macroautophagy is primarily a degradative process that cells use to break down their own components to recycle macromolecules and provide energy under stress conditions, and defects in macroautophagy lead to a wide range of diseases. Atg9, conserved
Autor:
Daniel J. Klionsky, Steven K. Backues
Publikováno v:
Autophagy. 8:1275-1278
Selective macroautophagy uses double-membrane vesicles, termed autophagosomes, to transport cytoplasmic pathogens, organelles and protein complexes to the vacuole for degradation. Autophagosomes are formed de novo by membrane fusion events at the pha
Macroautophagy (hereafter autophagy) is one of the major degradation systems in eukaryotic cells, and its dysfunction may result in diseases ranging from neurodegeneration to cancer. Although most of the autophagy-related (Atg) proteins that function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e94440e4889b86c81a6c21f741af652
https://europepmc.org/articles/PMC4835205/
https://europepmc.org/articles/PMC4835205/