Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Steven Joshua Romney"'
Autor:
Malini Rajan, Cole P Anderson, Paul M Rindler, Steven Joshua Romney, Maria C Ferreira dos Santos, Jason Gertz, Elizabeth A Leibold
Publikováno v:
eLife, Vol 8 (2019)
Iron is essential for survival of most organisms. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1. We previously showed that hif-1 mutants are deve
Externí odkaz:
https://doaj.org/article/ad372200c79b435392c72eb6ad1ee2f1
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002394 (2011)
Caenorhabditis elegans ftn-1 and ftn-2, which encode the iron-storage protein ferritin, are transcriptionally inhibited during iron deficiency in intestine. Intestinal specific transcription is dependent on binding of ELT-2 to GATA binding sites in a
Externí odkaz:
https://doaj.org/article/e977223e42b1412db692b3eeb97a28a4
Autor:
Malini Rajan, Cole P Anderson, Steven Joshua Romney, Maria Carolina Ferreira Dos Santos, Jason Gertz, Elizabeth A Leibold
Publikováno v:
The Journal of Immunology. 204:156.1-156.1
Iron is essential for survival of most organisms, but is toxic in excess. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1. We previously showed tha