Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Steven Jacobson"'
Autor:
Suchitra Mohanty, Sujit Suklabaidya, Alfonso Lavorgna, Takaharu Ueno, Jun-ichi Fujisawa, Nyater Ngouth, Steven Jacobson, Edward W. Harhaj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia/lymphoma (ATLL) and the neuroinflammatory disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Ta
Externí odkaz:
https://doaj.org/article/a04449588b6a4f07960705a393a0b93e
Autor:
Erik Nutma, Nurun Fancy, Maria Weinert, Stergios Tsartsalis, Manuel C. Marzin, Robert C. J. Muirhead, Irene Falk, Marjolein Breur, Joy de Bruin, David Hollaus, Robin Pieterman, Jasper Anink, David Story, Siddharthan Chandran, Jiabin Tang, Maria C. Trolese, Takashi Saito, Takaomi C. Saido, Katharine H. Wiltshire, Paula Beltran-Lobo, Alexandra Phillips, Jack Antel, Luke Healy, Marie-France Dorion, Dylan A. Galloway, Rochelle Y. Benoit, Quentin Amossé, Kelly Ceyzériat, Aurélien M. Badina, Enikö Kövari, Caterina Bendotti, Eleonora Aronica, Carola I. Radulescu, Jia Hui Wong, Anna M. Barron, Amy M. Smith, Samuel J. Barnes, David W. Hampton, Paul van der Valk, Steven Jacobson, Owain W. Howell, David Baker, Markus Kipp, Hannes Kaddatz, Benjamin B. Tournier, Philippe Millet, Paul M. Matthews, Craig S. Moore, Sandra Amor, David R. Owen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Microglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quanti
Externí odkaz:
https://doaj.org/article/6e4226618e024c669f4f230499a8801b
Autor:
Michelle L. Pleet, Joshua A. Welsh, Emily H. Stack, Sean Cook, Dove-Anna Johnson, Bryce Killingsworth, Tim Traynor, Annaliese Clauze, Randall Hughes, Maria Chiara Monaco, Nyater Ngouth, Joan Ohayon, Yoshimi Enose-Akahata, Avindra Nath, Irene Cortese, Daniel S. Reich, Jennifer C. Jones, Steven Jacobson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and objectivesExtracellular vesicles and particles (EVPs) are released from virtually all cell types, and may package many inflammatory factors and, in the case of infection, viral components. As such, EVPs can play not only a direct role
Externí odkaz:
https://doaj.org/article/abeca7654995444b82a2b718420705a4
Autor:
Jing-Ping Lin, Hannah M. Kelly, Yeajin Song, Riki Kawaguchi, Daniel H. Geschwind, Steven Jacobson, Daniel S. Reich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Studies of cell heterogeneity in white matter in primates have been limited to date. Here the authors describe a marmoset brain cell atlas that bridges rodent and human data, revealing strong gray-white matter glial segregation.
Externí odkaz:
https://doaj.org/article/5acbadad11ce435dbd202e080adc66cb
Autor:
William H. Theodore, Emily Leibovitch, Bridgette J. Billioux, Sara K. Inati, Kareem Zaghloul, John Heiss, William D. Gaillard, Steven Jacobson
Publikováno v:
Epilepsia Open, Vol 6, Iss 4, Pp 777-780 (2021)
Abstract We investigated the association between human herpesvirus 6 (HHV‐6) and mesial temporal sclerosis (MTS) in 87 patients who had surgery for drug‐resistant epilepsy. Fifty‐four had MTS, 22 focal cortical dysplasia (FCD), four tumors, thr
Externí odkaz:
https://doaj.org/article/ea9c2ef5a94f42dbb5e07d5bb9913093
Autor:
Yoshimi Enose‐Akahata, Bridgette Jeanne Billioux, Shila Azodi, Jennifer Dwyer, Ashley Vellucci, Nyater Ngouth, Satoshi Nozuma, Raya Massoud, Irene Cortese, Joan Ohayon, Steven Jacobson
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 1970-1985 (2021)
Abstract Objective Human T‐cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive myelopathy. A high proviral load (PVL) is one of the main risk factors for HAM/TSP. Recently, i
Externí odkaz:
https://doaj.org/article/de6377a3d42f49418079c39d1dc970fb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human T lymphotropic virus 1 (HTLV-1) is a human retrovirus identified as the causative agent in adult T-cell leukemia/lymphoma (ATL) and chronic-progressive neuroinflammatory disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TS
Externí odkaz:
https://doaj.org/article/ad565944f6334816bec2c61bdd050b78
Autor:
Elizabeth O. Akinsoji, Emily Leibovitch, B. Jeanne Billioux, Osorio Lopes Abath Neto, Abhik Ray‐Chaudhury, Sara K. Inati, Kareem Zaghloul, John Heiss, Steven Jacobson, William H. Theodore
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1674-1680 (2020)
Abstract Objective To study the effects of human herpes virus 6 (HHV‐6) on the hippocampal volume in patients with mesial temporal sclerosis (MTS). Background HHV‐6 may play an etiologic role in MTS. Previous studies found a possible association
Externí odkaz:
https://doaj.org/article/4cf510b6f0854f2e93926ce9c48216c4
Autor:
Natsuko Yamakawa, Naoko Yagishita, Tomohiro Matsuo, Junji Yamauchi, Takahiko Ueno, Eisuke Inoue, Ayako Takata, Misako Nagasaka, Natsumi Araya, Daisuke Hasegawa, Ariella Coler-Reilly, Shuntaro Tsutsumi, Tomoo Sato, Abelardo Araujo, Jorge Casseb, Eduardo Gotuzzo, Steven Jacobson, Fabiola Martin, Marzia Puccioni-Sohler, Graham P. Taylor, Yoshihisa Yamano, the Japan Clinical Research Group on HAM/TSP
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background Urinary dysfunction is one of the main features of human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, a comprehensive assessment of the severity is difficult because a standar
Externí odkaz:
https://doaj.org/article/f56ccd75e3b7408c8ffc25236c1648c9
Autor:
Yoshimi Enose-Akahata, Steven Jacobson
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately 10–20 million people worldwide. While the majority of infected people are asymptomatic carriers of HTLV-1, only 4% of infected people develop HTLV-1
Externí odkaz:
https://doaj.org/article/c23b7afead01494ebdabac8690ecc915