Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Steven J. Winder"'
Autor:
Valerie G. Brunton, Valerie J. Fincham, Gordon W. McLean, Steven J. Winder, Christos Paraskeva, John F. Marshall, Margaret C. Frame
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 3, Pp 215-226 (2001)
Integrins play an important role in tumour progression by influencing cellular responses and matrix-dependent adhesion. However, the regulation of matrix-dependent adhesion assembly in epithelial cells is poorly understood. We have investigated the i
Externí odkaz:
https://doaj.org/article/39c456e9a74a45b589692b899b3c24d7
Publikováno v:
Biochemical Journal. 396:307-316
Primary fibroblasts isolated from foetal mouse cornea, skin and tendon were subjected to linear shear stress and analysed for morphological parameters and by microarray, as compared with unstimulated controls. Approx. 350 genes were either up- or dow
Autor:
Kathryn R. Ayscough, Steven J. Winder
Publikováno v:
EMBO reports. 5:947-952
This meeting began with personal retrospective presentations from two of the founding fathers of European cytoskeletal research—V. Small (Vienna, Austria) and U. Lindberg (Stockholm, Sweden)—to commemorate the thirtieth anniversary of the first d
Publikováno v:
EMBO reports. 5:484-489
Dystroglycan is an important cell adhesion receptor linking the actin cytoskeleton, via utrophin and dystrophin, to laminin in the extracellular matrix. To identify adhesion-related signalling molecules associated with dystroglycan, we conducted a ye
Publikováno v:
The Journal of Cell Biology
Several determinants of aging, including metabolic capacity and genetic stability, are recognized in both yeast and humans. However, many aspects of the pathways leading to cell death remain to be elucidated. Here we report a role for the actin cytos
Autor:
Heather J. Spence, Jacqueline M. Cameron, Jane L. Ilsley, Steven J. Winder, Thomas J. Jess, Yun-Ju Chen
Publikováno v:
Biochemical Journal. 375:329-337
Dystroglycans are essential transmembrane adhesion receptors for laminin. α-Dystroglycan is a highly glycosylated extracellular protein that interacts with laminin in the extracellular matrix and the transmembrane region of β-dystroglycan. β-Dystr
Autor:
Steven J. Winder
Publikováno v:
Current Opinion in Cell Biology. 15:14-22
Structural advances in our understanding of the functions of the actin cytoskeleton have come from diverse sources. On the one hand, the determination of the structure of a bacterial actin-like protein MreB reveals the prokaryotic origins of the acti
Autor:
Steven J. Winder, Dušan Uhrín, Paul N. Barlow, Brian O. Smith, Janice Bramham, Julie L. Hodgkinson
Publikováno v:
Structure. 10:249-258
Calponin is involved in the regulation of contractility and organization of the actin cytoskeleton in smooth muscle cells. It is the archetypal member of the calponin homology (CH) domain family of actin binding proteins that includes cytoskeletal li
Publikováno v:
Journal of Structural Biology. 137:184-193
The spectrin family of proteins represents a discrete group of cytoskeletal proteins comprising principally alpha-actinin, spectrin, dystrophin, and homologues and isoforms. They all share three main structural and functional motifs, namely, the spec
Autor:
Steven J. Winder, John F. Marshall, Valerie J. Fincham, Christos Paraskeva, Gordon W. McLean, Margaret C. Frame, Valerie G. Brunton
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 3, Pp 215-226 (2001)
Integrins play an important role in tumour progression by influencing cellular responses and matrix-dependent adhesion. However, the regulation of matrix-dependent adhesion assembly in epithelial cells is poorly understood. We have investigated the i