Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Steven J. Sollot"'
Autor:
Nolan M. Winicki, Alay P. Nanavati, Christopher H. Morrell, Jack M. Moen, Jessie E. Axsom, Melissa Krawczyk, Natalia N. Petrashevskaya, Max G. Beyman, Christopher Ramirez, Irene Alfaras, Sarah J. Mitchell, Magdalena Juhaszova, Daniel R. Riordon, Mingyi Wang, Jing Zhang, Anthony Cerami, Michael Brines, Steven J. Sollott, Rafael de Cabo, Edward G. Lakatta
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
BackgroundAging is associated with increased levels of reactive oxygen species and inflammation that disrupt proteostasis and mitochondrial function and leads to organism-wide frailty later in life. ARA290 (cibinetide), an 11-aa non-hematopoietic pep
Externí odkaz:
https://doaj.org/article/a4bcde25e7274c8b9d6f0a3961d828c8
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Appropriate substrate selection between fats and glucose is associated with the success of interventions that maintain health such as exercise or caloric restriction, or with the severity of diseases such as diabetes or other metabolic disorders. Alt
Externí odkaz:
https://doaj.org/article/38c3de753c7946faa8adbc41820d86de
Autor:
Larissa Vetter, Sonia Cortassa, Brian O’Rourke, Antonis A. Armoundas, Djahida Bedja, Johann M. E. Jende, Martin Bendszus, Nazareno Paolocci, Steven J. Sollot, Miguel A. Aon, Felix T. Kurz
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Mitochondrial criticality describes a state in which the mitochondrial cardiac network under intense oxidative stress becomes very sensitive to small perturbations, leading from local to cell-wide depolarization and synchronized oscillations that may
Externí odkaz:
https://doaj.org/article/aae8c8d542f5459dacf8ca8678ef8bef
Autor:
Felix T. Kurz, Djahida Bedja, Miguel A. Aon, Johann M E Jende, Martin Bendszus, Larissa Vetter, Brian O'Rourke, Nazareno Paolocci, Antonis A. Armoundas, Steven J Sollot, Sonia Cortassa
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
Mitochondrial criticality describes a state in which the mitochondrial cardiac network under intense oxidative stress becomes very sensitive to small perturbations, leading from local to cell-wide depolarization and synchronized oscillations that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bbac81ee0afa3abff9e952cd4de49f
https://www.frontiersin.org/article/10.3389/fphys.2020.00175/full
https://www.frontiersin.org/article/10.3389/fphys.2020.00175/full
Autor:
Miguel A. Aon, Sonia Cortassa, Magdalena Juhaszova, José A. González-Reyes, Miguel Calvo-Rubio, José M. Villalba, Andrew D. Lachance, Bruce D. Ziman, Sarah J. Mitchell, Kelsey N. Murt, Jessie E. C. Axsom, Irene Alfaras, Steven L. Britton, Lauren G. Koch, Rafael de Cabo, Edward G. Lakatta, Steven J. Sollott
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity. Maximal respiratory rate capacity, a metabolic performance measure, is one of the best predictors of cardiovascular- and all-cause mortality. Rat
Externí odkaz:
https://doaj.org/article/14634003ef5e447c891b439fccd94408
Autor:
Daniele Mancardi, Pasquale Pagliaro, Lisa A. Ridnour, Carlo G. Tocchetti, Katrina Miranda, Magdalena Juhaszova, Steven J. Sollott, David A. Wink, Nazareno Paolocci
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 382 (2022)
Donors of nitroxyl (HNO), the one electron-reduction product of nitric oxide (NO.), positively modulate cardiac contractility/relaxation while limiting ischemia-reperfusion (I/R) injury. The mechanisms underpinning HNO anti-ischemic effects remain po
Externí odkaz:
https://doaj.org/article/107efb95a7d5486bbc86cbbac4645205