Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Steven J. Ryan"'
Autor:
Luis A. Williams, David J. Gerber, Amy Elder, Wei Chou Tseng, Valeriya Baru, Nathaniel Delaney-Busch, Christina Ambrosi, Gauri Mahimkar, Vaibhav Joshi, Himali Shah, Karthiayani Harikrishnan, Hansini Upadhyay, Sakthi H. Rajendran, Aishwarya Dhandapani, Joshua Meier, Steven J. Ryan, Caitlin Lewarch, Lauren Black, Julie Douville, Stefania Cinquino, Helen Legakis, Karsten Nalbach, Christian Behrends, Ai Sato, Lorenzo Galluzzi, Timothy W. Yu, Duncan Brown, Sudhir Agrawal, David Margulies, Alan Kopin, Graham T. Dempsey
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 189-203 (2022)
Mutations in the TECPR2 gene are the cause of an ultra-rare neurological disorder characterized by intellectual disability, impaired speech, motor delay, and hypotonia evolving to spasticity, central sleep apnea, and premature death (SPG49 or HSAN9;
Externí odkaz:
https://doaj.org/article/555fd4156baf47509e8e7211947eb238
Autor:
Luis A, Williams, David J, Gerber, Amy, Elder, Wei Chou, Tseng, Valeriya, Baru, Nathaniel, Delaney-Busch, Christina, Ambrosi, Gauri, Mahimkar, Vaibhav, Joshi, Himali, Shah, Karthiayani, Harikrishnan, Hansini, Upadhyay, Sakthi H, Rajendran, Aishwarya, Dhandapani, Joshua, Meier, Steven J, Ryan, Caitlin, Lewarch, Lauren, Black, Julie, Douville, Stefania, Cinquino, Helen, Legakis, Karsten, Nalbach, Christian, Behrends, Ai, Sato, Lorenzo, Galluzzi, Timothy W, Yu, Duncan, Brown, Sudhir, Agrawal, David, Margulies, Alan, Kopin, Graham T, Dempsey
Publikováno v:
Molecular therapy. Nucleic acids. 29
Mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f46faf63abd1f4135c97b4442e9dca4
https://pubmed.ncbi.nlm.nih.gov/35860385
https://pubmed.ncbi.nlm.nih.gov/35860385
Autor:
Steven J Ryan, David E Ehrlich, Aaron M Jasnow, Shabrine Daftary, Teresa E Madsen, Donald G Rainnie
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35320 (2012)
The basolateral complex of the amygdala (BLA) is a critical component of the neural circuit regulating fear learning. During fear learning and recall, the amygdala and other brain regions, including the hippocampus and prefrontal cortex, exhibit phas
Externí odkaz:
https://doaj.org/article/fb062987eccc4d94a1caad62db29032d
Autor:
Steven J. Ryan, David E. Ehrlich, Chenchen Li, Katelyn Gordon, Joanna Dabrowska, Aurélie Menigoz, Donald G. Rainnie, Rimi Hazra
Publikováno v:
Brain Structure and Function. 223:1731-1745
Previous studies have shown that exposure to stressful events can enhance fear-memory and anxiety-like behavior as well as increase synaptic plasticity in the rat basolateral amygdala (BLA). We have evidence that repeated unpredictable shock stress (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8b6677f1f6cc659b65d261a4b00078
https://doi.org/10.1007/s00429-017-1575-z
https://doi.org/10.1007/s00429-017-1575-z
Autor:
Larry J. Young, Varun Saravanan, Hasse Walum, Steven J. Ryan, Robert C. Liu, Wittney D. Mays, Donald G. Rainnie, Zachary V. Johnson, Elizabeth Amadei, Aaron C. Shpiner, Yong Jun Kwon
Publikováno v:
Nature
Adult pair bonding involves dramatic changes in the perception and valuation of another individual. One key change is that partners come to reliably activate the brain's reward system, although the precise neural mechanisms by which partners become r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb6255b2c05d072faf041d49ada8436
http://europepmc.org/articles/PMC5499998
http://europepmc.org/articles/PMC5499998
Autor:
Dina Simkin, Marc P. Forrest, Linda Laux, Timothy J. Searl, Michael Schwake, Evangelos Kiskinis, Owen B. McManus, Steven J. Ryan, John Millichap, Alfred L. George, Vaibhav Joshi, Hongkang Zhang, Peter Penzes, Gabriella L Robertson, Luis A. Williams, Brandon N Piyevsky, Graham T. Dempsey
Mutations in KCNQ2, which encodes a pore-forming K+ channel subunit responsible for neuronal M-current, cause neonatal epileptic encephalopathy, a complex disorder presenting with severe early-onset seizures and impaired neurodevelopment. The conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2558eb22e5116b64c261cb404ea2edb
https://doi.org/10.1101/538371
https://doi.org/10.1101/538371
Autor:
Aurélie Menigoz, Steven J. Ryan, Shivani Seth, Sarah E. Daniel, Donald G. Rainnie, Jidong Guo
Publikováno v:
Neuropharmacology
Distinct regions and cell types in the anterolateral group of the bed nucleus of the stria terminalis (BNST(ALG)) act to modulate anxiety in opposing ways. A history of chronic stress increases anxiety-like behavior with lasting electrophysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66490cda38d175faffb46354c1d5f0e7
https://pubmed.ncbi.nlm.nih.gov/30878403
https://pubmed.ncbi.nlm.nih.gov/30878403
Publikováno v:
Brain Structure and Function. 221:839-854
The basolateral nucleus of the amygdala (BLA) assigns emotional valence to sensory stimuli, and many amygdala-dependent behaviors undergo marked development during postnatal life. We recently showed principal neurons in the rat BLA undergo dramatic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7843199c0f8215df189556b96bc2090
https://doi.org/10.1007/s00429-014-0939-x
https://doi.org/10.1007/s00429-014-0939-x
Publikováno v:
Journal of Neurophysiology. 110:926-941
Many psychiatric disorders, including anxiety and autism spectrum disorders, have early ages of onset and high incidence in juveniles. To better treat and prevent these disorders, it is important to first understand normal development of brain circui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dc584b9da4ef4bc2057d57ac2aa8a1
https://doi.org/10.1152/jn.01105.2012
https://doi.org/10.1152/jn.01105.2012
Publikováno v:
The Journal of Physiology. 590:4819-4838
The basolateral amygdala (BLA) is critically involved in the pathophysiology of psychiatric disorders, which often emerge during brain development. Several studies have characterized postnatal changes to the morphology and biochemistry of BLA neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e85b32293330290b1eaf1db2140a884
https://doi.org/10.1113/jphysiol.2012.237453
https://doi.org/10.1113/jphysiol.2012.237453