Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Steven J. Kattman"'
Autor:
Praful Aggarwal, Amy Turner, Andrea Matter, Steven J Kattman, Alexander Stoddard, Rachel Lorier, Bradley J Swanson, Donna K Arnett, Ulrich Broeckel
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108051 (2014)
Cardiac hypertrophy is an independent risk factor for cardiovascular disease and heart failure. There is increasing evidence that microRNAs (miRNAs) play an important role in the regulation of messenger RNA (mRNA) and the pathogenesis of various card
Externí odkaz:
https://doaj.org/article/3e02f43e09874765b076cda38947c497
Autor:
Chad H. Koonce, Blake D. Anson, Steven J. Kattman, Brad Swanson, Shannon Einhorn, Arne Thompson, Coby B. Carlson, Natsuyo Aoyama, Steve Fiene
Publikováno v:
SLAS Discovery. 18:1203-1211
A major hurdle for cardiovascular disease researchers has been the lack of robust and physiologically relevant cell-based assays for drug discovery. Derivation of cardiomyocytes from human-induced pluripotent stem (iPS) cells at high purity, quality,
Autor:
Hans R. Schöler, Sigrid Fuchs, Ali El-Armouche, Alexander Becker, Thomas Rau, Thomas Eschenhagen, Michael Rubart, Dong Wook Han, Martin Zenke, Bernhard Unsöld, Claudia Lange, Udo Schumacher, Peter Christalla, Alec D. Witty, Steven J. Kattman, Michael Didié, Stephan Döker, Heimo Ehmke, Gordon Keller, Vijayakumar Muppala, Mark H. Soonpaa, Loren J. Field, Tao Yang, Cornelia Rudolph, Wolfram-Hubertus Zimmermann, Brigitte Schlegelberger, Wen Tao, Doris Steinemann, Qiong Lin, John A. Scherschel, Alexander P. Schwoerer
Publikováno v:
The Journal of Clinical Investigation, 123(3), 1285-1298. AMER SOC CLINICAL INVESTIGATION INC
Uniparental parthenotes are considered an unwanted byproduct of in vitro fertilization. In utero parthenote development is severely compromised by defective organogenesis and in particular by defective cardiogenesis. Although developmentally compromi
Autor:
Omar El-Mounayri, Masayoshi Ishida, Peter W. Zandstra, Hiroshi Sakamoto, Steven J. Kattman, Mansoor Husain, Gordon Keller, Minetaro Ogawa
Publikováno v:
Circulation Research. 110:253-264
Rationale: c-myb null (knockout) embryonic stem cells (ESC) can differentiate into cardiomyocytes but not contractile smooth muscle cells (SMC) in embryoid bodies (EB). Objective: To define the role of c-Myb in SMC differentiation from ESC. Methods a
Autor:
Alleyn T. Plowright, Anna Jonebring, Samantha Peel, Bradley J. Swanson, Blake D. Anson, Steven J. Kattman, Gabriella Brolén, Henrik Andersson, Chad H. Koonce, Lauren Drowley, Qing-Dong Wang
Several progenitor cell populations have been reported to exist in hearts that play a role in cardiac turnover and/or repair. Despite the presence of cardiac stem and progenitor cells within the myocardium, functional repair of the heart after injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93765297ee38941baa3051df07e9d96
https://europepmc.org/articles/PMC4729552/
https://europepmc.org/articles/PMC4729552/
Autor:
James Ellis, Alec D. Witty, Maryam Niapour, Gordon Keller, Steven J. Kattman, Mark Gagliardi, Akitsu Hotta, Nicole Dubois
Publikováno v:
Cell stem cell
Efficient differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) to a variety of lineages requires step-wise approaches replicating the key commitment stages found during embryonic development. Here we show that exp
Autor:
Venkatesh Mani, Steven Giovanonne, Anne Bystrup, Eric Adler, Perry Altman, Joseph A. Frank, Hans J. Weinmann, Wilson Young, Zahi A. Fayad, Gordon Keller, Steven J. Kattman, Karen C. Briley-Saebo
Publikováno v:
JACC: Cardiovascular Imaging. 2(9):1114-1122
Objectives The aim of the current study is to test the ability to label and detect murine embryonic stem cell–derived cardiovascular progenitor cells (ES-CPC) with cardiac magnetic resonance (CMR) using the novel contrast agent Gadofluorine M-Cy3 (
Autor:
Kristina Bonham, Loren J. Field, Els Henckaerts, Eric Adler, Geoffrey W. Abbott, Marion Kennedy, R. Michael Linden, Mark H. Soonpaa, Lei Yang, Torsten K. Roepke, Gordon Keller, Steven J. Kattman
Publikováno v:
Nature. 453:524-528
The functional heart is comprised of distinct mesoderm-derived lineages including cardiomyocytes, endothelial cells and vascular smooth muscle cells. Studies in the mouse embryo and the mouse embryonic stem cell differentiation model have provided ev
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 73:101-110
The discovery of human pluripotent stem cells has laid the foundation for an emerging new field of biomedical research that holds promise to develop models of human development and disease, establish new strategies for discovering and testing drugs,
Publikováno v:
Trends in Cardiovascular Medicine. 17:240-246
The fully formed heart is composed of diverse cell lineages including myocytes, endothelial cells, vascular smooth muscle cells, and fibroblasts that derive from distinct subsets of mesoderm during embryonic development. Findings from lineage tracing