Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Steven J. Kaczowka"'
Publikováno v:
Archaea, Vol 1, Iss 5, Pp 327-334 (2005)
The unusual physiological properties of archaea (e.g., growth in extreme salt concentration, temperature and pH) make them ideal platforms for metabolic engineering. Towards the ultimate goal of modifying an archaeon to produce bioethanol or other us
Externí odkaz:
https://doaj.org/article/a28d394cda264eff9f2cecfcb44678d3
Publikováno v:
Molecular Cancer Therapeutics. 8:1350-1362
Binding of activated α2-macroglobulin to GRP78 on the surface of human prostate cancer cells promotes proliferation by activating signaling cascades. Autoantibodies directed against the activated α2-macroglobulin binding site in the NH2-terminal do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c085df6876b0ff1e401a8b30b7ae796f
https://doi.org/10.1158/1535-7163.mct-08-0990
https://doi.org/10.1158/1535-7163.mct-08-0990
Publikováno v:
Cellular Signalling. 20:1459-1470
cAMP regulates a wide range of processes through its downstream effectors including PKA, and the family of guanine nucleotide exchange factors. Depending on the cell type, cAMP inhibits or stimulates growth and proliferation in a PKA-dependent or ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e78b0e60621a28fc31ef350945077a7
https://doi.org/10.1016/j.cellsig.2008.04.002
https://doi.org/10.1016/j.cellsig.2008.04.002
Autor:
Govind Gawdi, Steven J. Kaczowka, Salvatore V. Pizzo, Mario Gonzalez-Gronow, Fang Wang, Sturgis Payne
Publikováno v:
Journal of Biological Chemistry. 282:32811-32820
Both the voltage-dependent anion channel and the glucose-regulated protein 78 have been identified as plasminogen kringle 5 receptors on endothelial cells. In this study, we demonstrate that kringle 5 binds to a region localized in the N-terminal dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a990dd8e700df4709a47c6eea415a89
https://doi.org/10.1074/jbc.m703342200
https://doi.org/10.1074/jbc.m703342200
Publikováno v:
Journal of Bacteriology. 186:7763-7772
The halophilic archaeon Haloferax volcanii produces three different proteins (α1, α2, and β) that assemble into at least two 20S proteasome isoforms. This work reports the cloning and sequencing of two H. volcanii proteasome-activating nucleotidas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c00e2db4ddb3d80d370ceabea3ae1e0
https://doi.org/10.1128/jb.186.22.7763-7772.2004
https://doi.org/10.1128/jb.186.22.7763-7772.2004
Autor:
Julie A. Maupin-Furlow, Steven J. Kaczowka, Christopher J. Reuter, Malgorzata A. Gil, Kheir Zuobi-Hasona
Publikováno v:
Metabolic Engineering. 5:151-163
Archaea are a valuable source of enzymes for industrial and scientific applications because of their ability to survive extreme conditions including high salt and temperature. Thanks to advances in molecular biology and genetics, archaea are also att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::865dbb8e87609a7f519fd846b106b297
https://doi.org/10.1016/s1096-7176(03)00030-2
https://doi.org/10.1016/s1096-7176(03)00030-2
Publikováno v:
Journal of Bacteriology. 185:165-174
Haloferax volcanii , a halophilic archaeon, synthesizes three different proteins (α1, α2, and β) which are classified in the 20S proteasome superfamily. The α1 and β proteins alone form active 20S proteasomes; the role of α2, however, is not cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2036a204384f378bab4d93fa282faa
https://doi.org/10.1128/jb.185.1.165-174.2003
https://doi.org/10.1128/jb.185.1.165-174.2003
Autor:
Angel Blanco, Edith V. Bowers, Mario Gonzalez-Gronow, Maria del Pilar Fernandez, Rina Francos, Steven J. Kaczowka, Stephanie Cuchacovich, Miguel Cuchacovich, Salvatore V. Pizzo
Publikováno v:
Journal of neuroimmunology. 227(1-2)
Autistic children show elevated serum levels of autoantibodies to several proteins essential for the function of normal brains. The voltage-dependent anion channel (VDAC) and hexokinase-I, a VDAC protective ligand, were identified as targets of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaa604504e3525bbe1c15119956606f
https://pubmed.ncbi.nlm.nih.gov/20576296
https://pubmed.ncbi.nlm.nih.gov/20576296
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 13
Binding of plasminogen (Pg) to cell-surface receptors colocalized with plasminogen activators promotes Pg activation and enables cells to utilize the proteolytic activity of plasmin (Pm). Proteolysis by Pm is necessary in several physiological and pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbcda4bafd30b6425ee742f19f3d25a
https://pubmed.ncbi.nlm.nih.gov/17981653
https://pubmed.ncbi.nlm.nih.gov/17981653
Autor:
Lara S. Madding, Steven J. Kaczowka, George J. Cianciolo, Robert M. Kelly, Salvatore V. Pizzo, Kevin L. Epting
Publikováno v:
International journal of biological macromolecules. 42(1)
alpha2-Macroglobulin (alpha2M) is a 718 kDa homotetrameric proteinase inhibitor which undergoes a large conformational change upon activation. This conformational change can occur either by proteolytic attack on an approximately 40 amino acid stretch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3c0a309ccbfc9eb43eab2340de32db
https://pubmed.ncbi.nlm.nih.gov/17996290
https://pubmed.ncbi.nlm.nih.gov/17996290