Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven J. Hasal"'
Autor:
Patrick B. Johnston, Amanda F. Cashen, Petros G. Nikolinakos, Anne W. Beaven, Stefan Klaus Barta, Gajanan Bhat, Steven J. Hasal, Sven De Vos, Yasuhiro Oki, Changchun Deng, Francine M. Foss
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2021)
Abstract Background Belinostat is a histone deacetylase inhibitor approved for relapsed refractory peripheral T-cell lymphoma (PTCL). The primary objective of this study was to determine the maximum tolerated dose (MTD) of belinostat combined with CH
Externí odkaz:
https://doaj.org/article/af527152ded04cb9a0629860f5f6b4cf
Autor:
Patrick Wayne Cobb, Yong Wha Moon, Klára Mezei, István Láng, Gajanan Bhat, Shanta Chawla, Steven J. Hasal, Lee S. Schwartzberg
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6234-6243 (2020)
Abstract Eflapegrastim (Rolontis®) is a novel, long‐acting hematopoietic growth factor consisting of a recombinant human granulocyte‐colony stimulating factor (rhG‐CSF) analog conjugated to a human IgG4 Fc fragment via a short polyethylene gly
Externí odkaz:
https://doaj.org/article/88a9560255c6486fb96283aa83575700
Autor:
Inderjit Mehmi, Gajanan Bhat, Julio Antonio Peguero, Lee S. Schwartzberg, Zane Yang, Patrick Wayne Cobb, Shanta Chawla, Jayaram S. Bharadwaj, Osama Hlalah, Steven J. Hasal, Richy Agajanian, Alvaro Restrepo
Publikováno v:
The Oncologist
Background Eflapegrastim, a novel, long‐acting recombinant human granulocyte‐colony stimulating factor (rhG‐CSF), consists of a rhG‐CSF analog conjugated to a human IgG4 Fc fragment via a short polyethylene glycol linker. Preclinical and phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b0adae00c07af96a627a67b7b73197
https://doi.org/10.1634/theoncologist.2020-0105
https://doi.org/10.1634/theoncologist.2020-0105
Autor:
Steven J. Hasal, Lee S. Schwartzberg, Patrick Wayne Cobb, István Láng, Klára Mezei, Shanta Chawla, Yong Wha Moon, Gajanan Bhat
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 17, Pp 6234-6243 (2020)
Cancer Medicine, Vol 9, Iss 17, Pp 6234-6243 (2020)
Eflapegrastim (Rolontis®) is a novel, long‐acting hematopoietic growth factor consisting of a recombinant human granulocyte‐colony stimulating factor (rhG‐CSF) analog conjugated to a human IgG4 Fc fragment via a short polyethylene glycol linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3e56a5fee4ca4efc937177ae81a5f6
https://pubmed.ncbi.nlm.nih.gov/32687266
https://pubmed.ncbi.nlm.nih.gov/32687266
Autor:
A. Craig Lockhart, Nashat Y. Gabrail, Guru Reddy, Steven D. Weitman, Allen Yang, Anthony J. Olszanski, Steven J. Hasal, Jürgen Venitz, John Sarantopoulos, William Jeffery Edenfield, Kevin R. Kelly
Publikováno v:
Cancer Chemother Pharmacol
PURPOSE: Pralatrexate is a folate analogue indicated for the treatment of relapsed or refractory peripheral T-cell lymphoma. It has not been formally tested in patients with renal impairment. This study evaluated the pharmacokinetic (PK) profile of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39285cf286e794d01e7fbf9f88c78b1e
https://doi.org/10.1007/s00280-016-3142-3
https://doi.org/10.1007/s00280-016-3142-3
Publikováno v:
Toxicology Mechanisms and Methods. 12:119-133
Both cynomolgus and rhesus monkeys are utilized in chemical toxicity screening and drug development studies by industry and government laboratories. Along with better utilization of their tissue for in vivo studies, it would be advantageous if the ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24ae086ab4eae2f232ba8dd2d3491c6
https://doi.org/10.1080/10517230290075350
https://doi.org/10.1080/10517230290075350
Publikováno v:
Humanexperimental toxicology. 14(5)
1 Precision-cut liver slices, prepared from Sprague- Dawley and Fischer-344 rats and donated human liver tis sue, were used to identify differences in 1,2-dichloroben zene (1,2-DCB), 1,3-dichlorobenzene (1,3-DCB) and 1,4- dichlorobenzene (1,4-DCB) me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056e8ec00e8406102e73cc074bc535fa
https://pubmed.ncbi.nlm.nih.gov/7612303
https://pubmed.ncbi.nlm.nih.gov/7612303
Autor:
Robyn L. Fisher, Klaus Brendel, Mary S. Smith, A. Jay Gandolfi, Steven J. Hasal, Katherine S. Hasal
Publikováno v:
Humanexperimental toxicology. 13(7)
1 Successful use of agar-filled precision-cut rat lung slices in dynamic organ culture prompted the use of this technology with human lung. 2 The larger tissue mass of a human lung required that the trachea be cannulated with a balloon catheter and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a141cff0d9d33ab576731f21399b7c
https://pubmed.ncbi.nlm.nih.gov/7917502
https://pubmed.ncbi.nlm.nih.gov/7917502
Autor:
Robyn L. Fisher, Klaus Brendel, A. J. Gandolfi, Steven J. Hasal, Jeffery T. Sanuik, Katherine S. Hasal
Publikováno v:
Cryobiology. 30(3)
Tissue slices may provide a rapid and economical way of determining cold ischemic effects on human liver and kidney cell viability and metabolism. In contrast to isolated hepatocyte cultures, tissue slices offer an in vitro system which more closely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0237cf57a30fbc20f53f73086cce6e
https://pubmed.ncbi.nlm.nih.gov/8370311
https://pubmed.ncbi.nlm.nih.gov/8370311