High-Throughput Excipient Discovery Enables Oral Delivery of Poorly Soluble Pharmaceuticals

Autor: Jeffrey M. Ting, Swapnil Tale, Anatolii A. Purchel, Seamus D. Jones, Lakmini Widanapathirana, Zachary P. Tolstyka, Li Guo, Steven J. Guillaudeu, Frank S. Bates, Theresa M. Reineke

Publikováno v: ACS Central Science, Vol 2, Iss 10, Pp 748-755 (2016)

Externí odkaz: https://doaj.org/article/a7bcfd77168c4bb1b3a0616205793f50

Comparison of adipate and succinate polyesters in thermoplastic polyurethanes

Autor: Brian G. Landes, Benjamin L. Wendt, Steven J. Guillaudeu, Mark F. Sonnenschein

Publikováno v: Polymer. 51:3685-3692

Succinic acid derived from sugar is reportedly going to be an abundant and inexpensive feedstock for polymer synthesis in the near future. This article reports on succinic acid based polyester polyols prepared with butane diol and compares them to po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17ccdc8d485a2b94196b865c8d73c577
https://doi.org/10.1016/j.polymer.2010.06.012

PEGylated dendrimers with core functionality for biological applications

Autor: Yarah M. Haidar, Francis C. Szoka, Edward E. Dy, Megan E. Fox, Jean M. J. Frechet, Steven J. Guillaudeu

Publikováno v: Bioconjugate chemistry. 19(2)

The synthesis of a variety of core functionalized PEGylated polyester dendrimers and their in vitro and in vivo properties are described in this report. These water-soluble dendrimers have been designed to carry eight functional groups on their dendr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a3ca093221632672666377e8011e5a
https://pubmed.ncbi.nlm.nih.gov/18173227

Poly[{(BuSn)12O14(OH)6}(AMPS)2] and poly[methyl acrylate-co-{(BuSn)12O14(OH)6}(AMPS)2]: hybrid polymers cross-linked through electrostatic interactions

Autor: Delphine Veautier, Thierry Lalot, Steven J. Guillaudeu, François Ribot

Publikováno v: Journal of Materials Chemistry
Journal of Materials Chemistry, Royal Society of Chemistry, 2005, 15 (35-36), pp.3973-3978. ⟨10.1039/b507214j⟩

A butyltin oxo-cluster, {(BuSn)12O14(OH)6}2+, functionalized through electrostatic interactions with two 2-acrylamido-2-methyl-1-propanesulfonate anions (AMPS), has been synthesized and characterized by single crystal X-ray diffraction and multinucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef70b3a71cb10754628d7f6d1b16624
https://hal.sorbonne-universite.fr/hal-02435836

Biodegradable pH-Sensing Dendritic Nanoprobes for Near-Infrared Fluorescence Lifetime and Intensity Imaging

Autor: Steven J. Guillaudeu, Mikhail Y. Berezin, Jean M. J. Fréchet, Adah Almutairi, Samuel Achilefu

Publikováno v: Journal of the American Chemical Society. 130:444-445

The overproduction of acidic byproducts is implicated in the development of numerous diseases, and there is currently great interest in developing contrast agents that can image acidic tissue in vivo. Here we report a biodegradable pH-sensing near-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8344b2ffae8021b419e6ac1516910161
https://doi.org/10.1021/ja078147e