Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Steven J Mentzer"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011219 (2023)
In the normal lung, the dominant cable is an elastic "line element" composed of elastin fibers bound to a protein scaffold. The cable line element maintains alveolar geometry by balancing surface forces within the alveolus and changes in lung volume
Externí odkaz:
https://doaj.org/article/e7712ae88a3c4983920f4b1dc869e146
Autor:
Willi L Wagner, Yifan Zheng, Aidan Pierce, Maximilian Ackermann, Heinz Horstmann, Thomas Kuner, Paolo Ronchi, Yannick Schwab, Philip Konietzke, Felix Wünnemann, Mark O Wielpütz, Hans-Ulrich Kauczor, Steven J Mentzer
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238798 (2020)
The mesothelium is a dynamic and specialized tissue layer that covers the somatic cavities (pleural, peritoneal, and pericardial) as well as the surface of the visceral organs such as the lung, heart, liver, bowel and tunica vaginalis testis. The pot
Externí odkaz:
https://doaj.org/article/6da76f6207b6498d9b308fdb13a22005
Autor:
Alexandra B Ysasi, Willi L Wagner, Cristian D Valenzuela, Arne Kienzle, Andrew B Servais, Robert D Bennett, Akira Tsuda, Maximilian Ackermann, Steven J Mentzer
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177921 (2017)
In many mammals, including rodents and humans, removal of one lung results in the compensatory growth of the remaining lung; however, the mechanism of compensatory lung growth is unknown. Here, we investigated the changes in morphology and phenotype
Externí odkaz:
https://doaj.org/article/6a89162ff38343718113254434d57e3d
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(10)
COVID-19 has been associated with a range of illness severity-from minimal symptoms to life-threatening multisystem organ failure. The severe forms of COVID-19 appear to be associated with an angiocentric or vascular phase of the disease. In studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001273f8cc42dafe2b7fb24760433d36
https://pubmed.ncbi.nlm.nih.gov/35534210
https://pubmed.ncbi.nlm.nih.gov/35534210
Autor:
Maximilian Ackermann, Jan C. Kamp, Christopher Werlein, Claire L. Walsh, Helge Stark, Verena Prade, Rambabu Surabattula, Willi L. Wagner, Catherine Disney, Andrew J. Bodey, Thomas Illig, Diana J. Leeming, Morten A. Karsdal, Alexandar Tzankov, Peter Boor, Mark P. Kühnel, Florian P. Länger, Stijn E. Verleden, Hans M. Kvasnicka, Hans H. Kreipe, Axel Haverich, Stephen M. Black, Axel Walch, Paul Tafforeau, Peter D. Lee, Marius M. Hoeper, Tobias Welte, Benjamin Seeliger, Sascha David, Detlef Schuppan, Steven J. Mentzer, Danny D. Jonigk
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104296- (2022)
Summary: Background: COVID-19 is characterized by a heterogeneous clinical presentation, ranging from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with severe lung disease die from COVID-19 and a substantial number of
Externí odkaz:
https://doaj.org/article/b4f5f451eaf04dc4b18d8490c6c059a3
Autor:
Florian Peter Laenger, Nicolaus Schwerk, Jens Dingemann, Tobias Welte, Bernd Auber, Stijn Verleden, Maximilian Ackermann, Steven J. Mentzer, Matthias Griese, Danny Jonigk
Publikováno v:
European Respiratory Review, Vol 31, Iss 163 (2022)
Children's interstitial lung disease (chILD) encompasses a wide and heterogeneous spectrum of diseases substantially different from that of adults. Established classification systems divide chILD into conditions more prevalent in infancy and other co
Externí odkaz:
https://doaj.org/article/d0fec986e83341e381b23d9f6f5606aa
Autor:
Betty S, Liu, Cristian D, Valenzuela, Katherine L, Mentzer, Willi L, Wagner, Hassan A, Khalil, Zi, Chen, Maximilian, Ackermann, Steven J, Mentzer
Publikováno v:
Journal of Cellular Physiology. 238:274-284
Pleural epithelial adaptations to mechanical stress are relevant to both normal lung function and parenchymal lung diseases. Assessing regional differences in mechanical stress, however, has been complicated by the nonlinear stress-strain properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bd07f9bc9dfb0a1755fa00fc9d17f7
https://doi.org/10.1002/jcp.30927
https://doi.org/10.1002/jcp.30927
Autor:
Alexandra B. Ysasi, Robert D. Bennett, Willi Wagner, Cristian D. Valenzuela, Andrew B. Servais, Akira Tsuda, Saumyadipta Pyne, Shuqiang Li, Jonna Grimsby, Prapti Pokharel, Kenneth J. Livak, Maximilian Ackermann, Paul C. Blainey, Steven J. Mentzer
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Lung regeneration occurs in a variety of adult mammals after surgical removal of one lung (pneumonectomy). Previous studies of murine post-pneumonectomy lung growth have identified regenerative “hotspots” in subpleural alveolar ducts; however, th
Externí odkaz:
https://doaj.org/article/1d3219b82a0046cf97d080489744ae17
Autor:
Yifan Zheng, Aidan Pierce, Willi L. Wagner, Henrik V. Scheller, Debra Mohnen, Maximilian Ackermann, Steven J. Mentzer
Publikováno v:
Molecules, Vol 25, Iss 9, p 2108 (2020)
Biodegradable pectin polymers have been recommended for a variety of biomedical applications, ranging from the delivery of oral drugs to the repair of injured visceral organs. A promising approach to regulate pectin biostability is the blending of pe
Externí odkaz:
https://doaj.org/article/a3d27855c41d4e6a8e3de3104a846504
Autor:
Christine Byun, Yifan Zheng, Aidan Pierce, Willi L. Wagner, Henrik V. Scheller, Debra Mohnen, Maximilian Ackermann, Steven J. Mentzer
Publikováno v:
Molecules, Vol 25, Iss 1, p 75 (2019)
Pectin binds the mesothelial glycocalyx of visceral organs, suggesting its potential role as a mesothelial sealant. To assess the mechanical properties of pectin films, we compared pectin films with a less than 50% degree of methyl esterification (lo
Externí odkaz:
https://doaj.org/article/12b86da4e9f945269af4e76a4f93cb11