Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Steven J Collins"'
Autor:
Helmut Butzkueven, Frank Gaillard, Robb Wesselingh, Victoria Lewis, Steven J Collins, Sarah Holper
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 1 (2022)
Background A diagnosis of variant Creutzfeldt-Jakob disease (vCJD), the zoonotic prion disease related to transmission of bovine spongiform encephalopathy, can carry enormous public health ramifications. Until recently, all vCJD clinical cases were c
Externí odkaz:
https://doaj.org/article/e3caa59ba287479bb8b3541895676f6f
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134680 (2015)
Internal cleavage of the cellular prion protein generates two well characterised N-terminal fragments, N1 and N2. These fragments have been shown to bind to anionic phospholipids at low pH. We sought to investigate binding with other lipid moieties a
Externí odkaz:
https://doaj.org/article/a7de4e258aaa4f329cb54e11c5ed9461
Autor:
Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Ángel Carracedo, Sven J van der Lee, Thomas Ströbel, Fernando Rivadeneira, Albert Hofman, Stéphane Haïk, Onofre Combarros, José Berciano, Andre G Uitterlinden, Steven J Collins, Herbert Budka, Jean-Philippe Brandel, Jean Louis Laplanche, Maurizio Pocchiari, Inga Zerr, Richard S G Knight, Robert G Will, Cornelia M van Duijn
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123654 (2014)
We performed a genome-wide association (GWA) study in 434 sporadic Creutzfeldt-Jakob disease (sCJD) patients and 1939 controls from the United Kingdom, Germany and The Netherlands. The findings were replicated in an independent sample of 1109 sCJD an
Externí odkaz:
https://doaj.org/article/cce2b1a8c1a44c87b1539cdd95ccb3a7
Autor:
Yi‐En Quek, Yi Leng Fung, Pierrick Bourgeat, Simon J. Vogrin, Steven J. Collins, Stephen C. Bowden
Publikováno v:
Brain and Behavior, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction The current study examined the contributions of comprehensive neuropsychological assessment and volumetric assessment of selected mesial temporal subregions on structural magnetic resonance imaging (MRI) to identify patients wit
Externí odkaz:
https://doaj.org/article/10f0823dda2d40129bb7f999f45e3fe4
Autor:
Cathryn L Haigh, Steven J Collins
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Externí odkaz:
https://doaj.org/article/d4856b1724fb44bcb939ba70f5751b85
Autor:
James M Moore, Natalia A Rabaia, Leslie E Smith, Sara Fagerlie, Kay Gurley, Dmitry Loukinov, Christine M Disteche, Steven J Collins, Christopher J Kemp, Victor V Lobanenkov, Galina N Filippova
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34915 (2012)
CTCF is a highly conserved, multifunctional zinc finger protein involved in critical aspects of gene regulation including transcription regulation, chromatin insulation, genomic imprinting, X-chromosome inactivation, and higher order chromatin organi
Externí odkaz:
https://doaj.org/article/c4cf1095458740fb87a86f08b93e1afd
Autor:
Victoria Lewis, Isobel J Whitehouse, Herbert Baybutt, Jean C Manson, Steven J Collins, Nigel M Hooper
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31754 (2012)
There is increasing evidence of molecular and cellular links between Alzheimer's disease (AD) and prion diseases. The cellular prion protein, PrP(C), modulates the post-translational processing of the AD amyloid precursor protein (APP), through its i
Externí odkaz:
https://doaj.org/article/08e189dc9f87415ca7e578f29a71edff
Autor:
Victoria A Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M Klemm, James D Stewart, Colin L Masters, David E Hoke, Steven J Collins, Andrew F Hill
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12351 (2010)
BackgroundThe accumulation of protease resistant conformers of the prion protein (PrP(res)) is a key pathological feature of prion diseases. Polyanions, including RNA and glycosaminoglycans have been identified as factors that contribute to the propa
Externí odkaz:
https://doaj.org/article/1053ce57cef44fceb9562c4a059e980a
Autor:
Zitianyu Wang, Victoria Lewis, Christiane Stehmann, Shiji Varghese, Matteo Senesi, Amelia McGlade, Laura J. Ellett, James D. Doecke, Dhamidhu Eratne, Dennis Velakoulis, Colin L. Masters, Steven J. Collins, Qiao‐Xin Li
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract Most suspected Creutzfeldt‐Jakob disease (CJD) cases are eventually diagnosed with other disorders. We assessed the utility of investigating Alzheimer's disease (AD) biomarkers and neurofilament light (NfL) in patients when CJD is suspecte
Externí odkaz:
https://doaj.org/article/bb39afaf574a49de915fe1b741f84a76
Autor:
Steven J. Collins, Jutong Si
Ca2+ signaling is an important component of signal transduction pathways regulating B and T lymphocyte proliferation, but the functional role of Ca2+ signaling in regulating myeloid leukemia cell proliferation has been largely unexplored. We observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120a21c71b80e1cee4ab6ed675c35241
https://doi.org/10.1158/0008-5472.c.6497205.v1
https://doi.org/10.1158/0008-5472.c.6497205.v1