Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Steven J, Ludtke"'
Autor:
Gerard J. Kleywegt, Paul D. Adams, Sarah J. Butcher, Catherine L. Lawson, Alexis Rohou, Peter B. Rosenthal, Sriram Subramaniam, Maya Topf, Sanja Abbott, Philip R. Baldwin, John M. Berrisford, Gérard Bricogne, Preeti Choudhary, Tristan I. Croll, Radostin Danev, Sai J. Ganesan, Timothy Grant, Aleksandras Gutmanas, Richard Henderson, J. Bernard Heymann, Juha T. Huiskonen, Andrei Istrate, Takayuki Kato, Gabriel C. Lander, Shee-Mei Lok, Steven J. Ludtke, Garib N. Murshudov, Ryan Pye, Grigore D. Pintilie, Jane S. Richardson, Carsten Sachse, Osman Salih, Sjors H. W. Scheres, Gunnar F. Schroeder, Carlos Oscar S. Sorzano, Scott M. Stagg, Zhe Wang, Rangana Warshamanage, John D. Westbrook, Martyn D. Winn, Jasmine Y. Young, Stephen K. Burley, Jeffrey C. Hoch, Genji Kurisu, Kyle Morris, Ardan Patwardhan, Sameer Velankar
Publikováno v:
IUCrJ, Vol 11, Iss 2, Pp 140-151 (2024)
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, m
Externí odkaz:
https://doaj.org/article/0e43f020fe4a4894b6f5aa6a5fd3dc2f
Autor:
Saman Majeed, Lan Dang, Md Majharul Islam, Olamide Ishola, Peter P. Borbat, Steven J. Ludtke, Elka R. Georgieva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract We report our findings on the assembly of the HIV-1 protein Vpu into soluble oligomers. Vpu is a key HIV-1 protein. It has been considered exclusively a single-pass membrane protein. Previous observations show that this protein forms stable
Externí odkaz:
https://doaj.org/article/752b4918c40d41d184ea0c0c60b17618
Autor:
Zhili Yu, Yaoming Wu, Muyuan Chen, Tong Huo, Wei Zheng, Steven J. Ludtke, Xiaodong Shi, Zhao Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The GspD secretin is the outer membrane channel of the bacterial type II secretion system (T2SS) which secrets diverse toxins that cause severe diseases such as diarrhea and cholera. GspD needs to translocate from the inner to the outer memb
Externí odkaz:
https://doaj.org/article/d6b59fe2ee144066854c43692692aa97
Autor:
Cristina Jiménez-Ortigosa, Jennifer Jiang, Muyuan Chen, Xuyuan Kuang, Kelley R. Healey, Paul Castellano, Nikpreet Boparai, Steven J. Ludtke, David S. Perlin, Wei Dai
Publikováno v:
Journal of Fungi, Vol 10, Iss 3, p 201 (2024)
The authors wish to update the article title to “Cryo-Electron Tomography of Candida glabrata Plasma Membrane Proteins” [...]
Externí odkaz:
https://doaj.org/article/5b1b762bb45a4c51b5a604547fdae6c2
Autor:
Guizhen Fan, Mariah R. Baker, Lara E. Terry, Vikas Arige, Muyuan Chen, Alexander B. Seryshev, Matthew L. Baker, Steven J. Ludtke, David I. Yule, Irina I. Serysheva
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here authors report cryo-EM structures of IP3R1 which provide atomic details of IP3, Ca2+ and ATP binding. Molecular motions of key domains and sidechains were found to regulate ligand binding and gating, which are validated by functional assays.
Externí odkaz:
https://doaj.org/article/19978619640c40e4bd70b573581c08b9
Autor:
Zhili Yu, Yaoming Wu, Muyuan Chen, Tong Huo, Wei Zheng, Steven J. Ludtke, Xiaodong Shi, Zhao Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/6ce0f7546f544a409b61c1d68fa516ee
Autor:
Yuewei Wang, Tong Huo, Yu-Jung Tseng, Lan Dang, Zhili Yu, Wenjuan Yu, Zachary Foulks, Rebecca L. Murdaugh, Steven J. Ludtke, Daisuke Nakada, Zhao Wang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Wang et al characterise platelets in a mouse model of acute myeloid leukemia (AML) using Cryo-electron tomography (Cryo-ET) and find that 23% of platelets in pre-leukemic cells exhibit abnormal, round mitochondria with unfolded cristae. They also det
Externí odkaz:
https://doaj.org/article/b644d925817f401c8f961301fc653c0d
Autor:
Xiaodong Shi, Muyuan Chen, Zhili Yu, James M. Bell, Hans Wang, Isaac Forrester, Heather Villarreal, Joanita Jakana, Dijun Du, Ben F. Luisi, Steven J. Ludtke, Zhao Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-6 (2019)
Multidrug efflux pumps actively expel a wide range of toxic substrates from bacteria and play a major role in drug resistance. Here authors show the in situ structure of the efflux pump AcrAB-TolC obtained by electron cryo-tomography and subtomogram
Externí odkaz:
https://doaj.org/article/28c29f6371ef4ce0931bd60ea29799b1
Autor:
Cristina Jiménez-Ortigosa, Jennifer Jiang, Muyuan Chen, Xuyuan Kuang, Kelley R. Healey, Paul Castellano, Nikpreet Boparai, Steven J. Ludtke, David S. Perlin, Wei Dai
Publikováno v:
Journal of Fungi, Vol 7, Iss 2, p 120 (2021)
Fungal plasma membrane proteins have long been recognized as targets for the development of antifungal agents. Despite recent progress in experimental approaches and computational structural predictions, our knowledge of the structural dynamics and s
Externí odkaz:
https://doaj.org/article/9898cecc6f06411e8de371800df15b72
Autor:
Lan Dang, Steven J Ludtke
Publikováno v:
Microscopy and Microanalysis. 28:1514-1516