Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Steven J, Kridel"'
Autor:
Aaron M. Mohs, Steven J. Kridel, Pankaj K. Singh, Bowen Qi, Megan B. Holmes, Tanner K. Hill, Amanda L. Davis, Joshua J. Souchek
Supplementary Figure S1. Dose-response curves of combinations of orlistat or NanoOrl with taxanes; Supplementary Figure S2. Synergy analysis with Combenefit (Loewe model);Supplementary Figure S3. Synergy analysis with Combenefit [Highest Single Agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9ee730e971511a67e742e5ee3159cd
https://doi.org/10.1158/1535-7163.22508233.v1
https://doi.org/10.1158/1535-7163.22508233.v1
Supplementary Fig. from Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057c13774c86d6eafdfd38ae74a5cc26
https://doi.org/10.1158/1535-7163.22483299.v1
https://doi.org/10.1158/1535-7163.22483299.v1
Fatty acid synthase (FASN) is the terminal enzyme responsible for fatty acid synthesis and is up-regulated in tumors of various origins to facilitate their growth and progression. Because of several reports linking the FASN and proteasome pathways, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc45d0702fcbddc36d8c8a148556bf37
https://doi.org/10.1158/1535-7163.c.6531111
https://doi.org/10.1158/1535-7163.c.6531111
Autor:
Constantinos Koumenis, Albert C. Koong, Michael Olson, Michael Spiotto, Steven J. Kridel, Andrew T. Segan, Jiangbin Ye, Diane R. Fels
Supplementary Materials, Figures 1-6 from Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0883ec2ba47bc6b27e9a3570cd4b97a5
https://doi.org/10.1158/0008-5472.22377161
https://doi.org/10.1158/0008-5472.22377161
Autor:
Ashish Kumar, Pawan Kumar, Mitu Sharma, Susy Kim, Sangeeta Singh, Steven J. Kridel, Gagan Deep
Publikováno v:
Cancer drug resistance (Alhambra, Calif.). 5(3)
Aim: The development of chemotherapy resistance is the major obstacle in the treatment of advanced prostate cancer (PCa). Extracellular vesicles (EVs) secretion plays a significant role among different mechanisms contributing to chemoresistance. Henc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da76f7461e2079ed65b2ed2a4444febc
https://pubmed.ncbi.nlm.nih.gov/36176762
https://pubmed.ncbi.nlm.nih.gov/36176762
Autor:
Hesham Afify, Ammar Yasser Abdulfattah, Manish S. Bharadwaj, Bailey Warren, Randy Casals, Daniela Gonzalez, Sameh Almousa, Neveen Said, Kendall L. Langsten, Steven J. Kridel, Alia Ghoneum
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Bladder cancer (BCa) is the most common malignancy of the urinary system with increasing incidence, mortality, and limited treatment options. Therefore, it is imperative to validate preclinical models that faithfully represent BCa cellular, molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c5232340dddd52ce529bf2611be6d6
http://europepmc.org/articles/PMC8585868
http://europepmc.org/articles/PMC8585868
Autor:
Chuan Gao, Nan Wang, Xiuqing Guo, Julie T Ziegler, Kent D Taylor, Anny H Xiang, Yang Hai, Steven J Kridel, Jerry L Nadler, Fouad Kandeel, Leslie J Raffel, Yii-Der I Chen, Jill M Norris, Jerome I Rotter, Richard M Watanabe, Lynne E Wagenknecht, Donald W Bowden, Elizabeth K Speliotes, Mark O Goodarzi, Carl D Langefeld, Nicholette D Palmer
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0134649 (2015)
Obesity is growing epidemic affecting 35% of adults in the United States. Previous genome-wide association studies (GWAS) have identified numerous loci associated with obesity. However, the majority of studies have been completed in Caucasians focusi
Externí odkaz:
https://doaj.org/article/46ee037fe6bb4cd9a6d303698c6c7525
Autor:
Justin W. Hines, Naresh Damuka, Jaya Prabhakaran, J. S. Dileep Kumar, Kiran Kumar Solingapuram Sai, Steven J. Kridel, J. John Mann, Akiva Mintz
Publikováno v:
International Journal of Pharmacy and Pharmaceutical Sciences. :43-47
Objective: The objective of this study was to evaluate the uptake and specificity of [11C]MPC-6827, a MT targeted PET ligand in prostate, glioblastoma and breast cancer cells. Methods: [11C]MPC-6827 was synthesized by reacting corresponding desmethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c5bd57de04961e45a3530a5d9d857ec
https://doi.org/10.22159/ijpps.2020v12i1.35657
https://doi.org/10.22159/ijpps.2020v12i1.35657
Autor:
Kristen E N Scott, Frances B Wheeler, Amanda L Davis, Michael J Thomas, James M Ntambi, Darren F Seals, Steven J Kridel
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29761 (2012)
Invadopodia are membrane protrusions that facilitate matrix degradation and cellular invasion. Although lipids have been implicated in several aspects of invadopodia formation, the contributions of de novo fatty acid synthesis and lipogenesis have no
Externí odkaz:
https://doaj.org/article/31f2a5c6add946bd82d4554b4f735d64
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40195 (2012)
Tumor cells have increased metabolic requirements to maintain rapid growth. In particular, a highly lipogenic phenotype is a hallmark of many tumor types, including prostate. Cancer cells also have increased turnover of nicotinamide adenine dinucleot
Externí odkaz:
https://doaj.org/article/f15d548e250040ac91c57d3dfa22aaea