Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Steven J, Hughes"'
Autor:
Song Han, Steven J Hughes, Gerik W Tushoski-Alemán, Alexandra J Crespin, Chibeze J Oguejiofor, Dominique D Szymkiewicz, Kelly M Herremans
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Objectives This systematic review aims to evaluate the methodology used in pancreatic cancer (PC) randomised controlled trials (RCTs) measuring quality of life (QOL) and focuses on the type, frequency, survey compliance and duration of these assessme
Externí odkaz:
https://doaj.org/article/b1a25df2c502421cb9113e809c1253c1
Autor:
Song Han, Gerik W. Tushoski-Alemán, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Zhiguang Huo, Jonathan Licht, Thomas J. George, Carmen Allegra, Jose G. Trevino, Steven J. Hughes
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101070- (2025)
Oncogenic KRAS signaling plays a critical role in pancreatic ductal adenocarcinoma (PDAC) biology. Recent studies indicate that the combination of MEK and BCL-xL inhibition is synthetically lethal and holds promise for some types of solid cancers, ho
Externí odkaz:
https://doaj.org/article/191df517e9ab4a0b927c1c49c80b247d
Autor:
Andrea N. Riner, Kelly M. Herremans, Vignesh Vudatha, Song Han, Xufeng Qu, Jinze Liu, Nitai Mukhopadhyay, Devon C. Freudenberger, Thomas J. George, Sarah M. Judge, Andrew R. Judge, Steven J. Hughes, Jose G. Trevino
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 149-158 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is highly associated with cachexia and weight loss, which is driven by the tumour's effect on the body. Data are lacking on differences in these metrics based on PDAC anatomic location. We h
Externí odkaz:
https://doaj.org/article/8b79d152af8740b48f6cb1720b637f74
Autor:
Gerik W Tushoski-Alemán, Kelly M Herremans, Patrick W Underwood, Ashwin Akki, Andrea N Riner, Jose G Trevino, Song Han, Steven J Hughes
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297325 (2024)
BackgroundPancreatic ductal adenocarcinomas (PDAC) have heterogeneous tumor microenvironments relatively devoid of infiltrating immune cells. We aimed to quantitatively assess infiltrating CD3+ and CD8+ lymphocytes in a treatment-naïve patient cohor
Externí odkaz:
https://doaj.org/article/f09d8e56361249bc9e2342aa74cff5e4
Autor:
Kelly M. Herremans, Andrea N. Riner, Miles E. Cameron, Kelley L. McKinley, Eric W. Triplett, Steven J. Hughes, Jose G. Trevino
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Pancreatic cancer is a deadly disease with limited diagnostic and treatment options. Not all populations are affected equally, as disparities exist in pancreatic cancer prevalence, treatment and outcomes. Recently, next-generation sequencing
Externí odkaz:
https://doaj.org/article/e4cf8913392a4a998482830b4459af2c
Autor:
Kelly M. Herremans, Andrea N. Riner, Angel M. Charles, Jeremy A. Balch, Vignesh Vudatha, Devon C. Freudenberger, Ibrahim Nassour, Steven J. Hughes, Jose G. Trevino, Tyler J. Loftus
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/2043b47a19954aeb9da384a43df21094
Autor:
Kelley N. L. McKinley, Kelly M. Herremans, Andrea N. Riner, Vignesh Vudatha, Devon C. Freudenberger, Steven J. Hughes, Eric W. Triplett, Jose G. Trevino
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1466 (2023)
Oral dysbiosis has long been associated with pancreatic ductal adenocarcinoma (PDAC). In this work, we explore the relationship between the oral and tumor microbiomes of patients diagnosed with PDAC. Salivary and tumor microbiomes were analyzed using
Externí odkaz:
https://doaj.org/article/a0b8e7920ad14a6682f91381e830ba9b
Autor:
Kelly M. Herremans, Dominique D. Szymkiewicz, Andrea N. Riner, Riley P. Bohan, Gerik W. Tushoski, Aaron M. Davidson, XiangYang Lou, Man Chong Leong, Bayli DiVita Dean, Michael Gerber, Patrick W. Underwood, Song Han, Steven J. Hughes
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 28, Iss , Pp 100789- (2022)
Interleukin-1 (IL-1) plays a key role in carcinogenesis and several IL-1-targeted therapeutics are under investigation for the treatment of pancreatic ductal adenocarcinoma (PDAC). We sought to broaden our understanding of how the family of IL-1 liga
Externí odkaz:
https://doaj.org/article/91f227e1ab2c44569e5e6beb00ae00b3
Autor:
Alexandra D Ladd, Jorge Zarate Rodriguez, Duncan Lewis, Curtis Warren, Sergio Duarte, Tyler J Loftus, Ibrahim Nassour, Daiki Soma, Steven J Hughes, Chet W Hammill, Ali Zarrinpar
Publikováno v:
Journal of the American College of Surgeons. 236:711-717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c7616298a4540f1da3d5c5ba6e833c
https://doi.org/10.1097/xcs.0000000000000553
https://doi.org/10.1097/xcs.0000000000000553
Autor:
Ellery Altshuler, Andrea N. Riner, Kelly M. Herremans, Thomas J. George, Sherise C. Rogers, Alessandro Paniccia, Steven J. Hughes, Jesus C. Fabregas, Ibrahim Nassour
Publikováno v:
Journal of Gastrointestinal Oncology. 13:3207-3215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6bba9caa8046db5719cc8055af391a8
https://doi.org/10.21037/jgo-22-434
https://doi.org/10.21037/jgo-22-434