Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Steven J, Bensinger"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The luminal surface of the endothelium is exposed to dynamic blood flow patterns that are known to affect endothelial cell phenotype. While many studies have documented the phenotypic changes by gene or protein expression, less is known about the rol
Externí odkaz:
https://doaj.org/article/2dbea7e9f32843fc8f11cc425472b336
Autor:
Alexander H. Lee, Lu Sun, Aaron Y. Mochizuki, Jeremy G. Reynoso, Joey Orpilla, Frances Chow, Jenny C. Kienzler, Richard G. Everson, David A. Nathanson, Steven J. Bensinger, Linda M. Liau, Timothy Cloughesy, Willy Hugo, Robert M. Prins
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Immune-checkpoint blockade has shown limited benefits in patients with glioblastoma. To understand how the composition of the tumor immune microenvironment might limit clinical responses, here the authors present a high dimensional profiling of the i
Externí odkaz:
https://doaj.org/article/bc4276916a1e42c19b71f6a03a3eba26
Autor:
Yvonne N. Flores, Aryana T. Amoon, Baolong Su, Rafael Velazquez-Cruz, Paula Ramírez-Palacios, Jorge Salmerón, Berenice Rivera-Paredez, Janet S. Sinsheimer, Aldons J. Lusis, Adriana Huertas-Vazquez, Sammy Saab, Beth A. Glenn, Folasade P. May, Kevin J. Williams, Roshan Bastani, Steven J. Bensinger
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, and diabetes. The aim
Externí odkaz:
https://doaj.org/article/37bef688082e4aa795640c4fb24a17e1
Autor:
Shen Li, Tomohiro Yokota, Ping Wang, Johanna ten Hoeve, Feiyang Ma, Thuc M. Le, Evan R. Abt, Yonggang Zhou, Rimao Wu, Maxine Nanthavongdouangsy, Abraham Rodriguez, Yijie Wang, Yen-Ju Lin, Hayato Muranaka, Mark Sharpley, Demetrios T. Braddock, Vicky E. MacRae, Utpal Banerjee, Pei-Yu Chiou, Marcus Seldin, Dian Huang, Michael Teitell, Ilya Gertsman, Michael Jung, Steven J. Bensinger, Robert Damoiseaux, Kym Faull, Matteo Pellegrini, Aldons J. Lusis, Thomas G. Graeber, Caius G. Radu, Arjun Deb
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Various populations of cells are recruited to the heart after cardiac injury, but little is known about whether cardiomyocytes directly regulate heart repair. Using a murine model of ischemic cardiac injury, we demonstrate that cardiomyocytes play a
Externí odkaz:
https://doaj.org/article/4f249dd668874f6a904b120bd8b43144
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100235- (2021)
Summary: Immune cells, such as macrophages, reprogram their lipid metabolism in response to the activation of pattern recognition receptors (e.g., TLRs, NLRs) and cytokine receptors (e.g., interferons, interleukins). Profiling these changes can be ac
Externí odkaz:
https://doaj.org/article/8bd1f09bb84349a581837452910e563d
Autor:
Xu Xiao, John Paul Kennelly, Alessandra Ferrari, Bethan L. Clifford, Emily Whang, Yajing Gao, Kevin Qian, Jaspreet Sandhu, Kelsey E. Jarrett, Madelaine C. Brearley-Sholto, Alexander Nguyen, Rohith T. Nagari, Min Sub Lee, Sicheng Zhang, Thomas A. Weston, Stephen G. Young, Steven J. Bensinger, Claudio J. Villanueva, Thomas Q. de Aguiar Vallim, Peter Tontonoz
Publikováno v:
Nature Metabolism. 5:165-181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf87f0f77365706f3d61f11548901e5
https://doi.org/10.1038/s42255-022-00722-6
https://doi.org/10.1038/s42255-022-00722-6
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 2, Pp 460-468 (2017)
Stable isotope labeling has become an important methodology for determining lipid metabolic parameters of normal and neoplastic cells. Conventional methods for fatty acid and cholesterol analysis have one or more issues that limit their utility for i
Externí odkaz:
https://doaj.org/article/17de5abbf6d94b35bf08eb22491cb285
Autor:
Joseph P. Argus, Moses Q. Wilks, Quan D. Zhou, Wei Yuan Hsieh, Elvira Khialeeva, Xen Ping Hoi, Viet Bui, Shili Xu, Amy K. Yu, Eric S. Wang, Harvey R. Herschman, Kevin J. Williams, Steven J. Bensinger
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2919-2934.e8 (2018)
Summary: It is well understood that fatty acids can be synthesized, imported, and modified to meet requisite demands in cells. However, following the movement of fatty acids through the multiplicity of these metabolic steps has remained difficult. To
Externí odkaz:
https://doaj.org/article/482a607cb48f49f9b41f5484a29a328c
Autor:
Autumn G. York, Mathias H. Skadow, Rihao Qu, Joonseok Oh, Walter K. Mowel, J. Richard Brewer, Eleanna Kaffe, Kevin J. Williams, Yuval Kluger, Jason M. Crawford, Stephen T. Smale, Steven J. Bensinger, Richard A. Flavell
Publikováno v:
bioRxiv
Unchecked chronic inflammation is the underlying cause of many diseases, ranging from inflammatory bowel disease to obesity and neurodegeneration. Given the deleterious nature of unregulated inflammation, it is not surprising that cells have acquired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc43508e567e65fcce448ea1f93699a
https://doi.org/10.1101/2023.05.07.539780
https://doi.org/10.1101/2023.05.07.539780
Autor:
Jenna K. Minami, Danielle Morrow, Nicholas A. Bayley, Elizabeth G. Fernandez, Jennifer J. Salinas, Christopher Tse, Henan Zhu, Baolong Su, Rhea Plawat, Anthony Jones, Alessandro Sammarco, Linda M. Liau, Thomas G. Graeber, Kevin J. Williams, Timothy F. Cloughesy, Scott J. Dixon, Steven J. Bensinger, David A. Nathanson
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a444e1faec9ea0f7bfdb27e1c0ee72b
https://doi.org/10.1016/j.ccell.2023.05.001
https://doi.org/10.1016/j.ccell.2023.05.001