Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Steven I. Wang"'
Publikováno v:
Current gene therapy. 21(4)
Aims: This study aims to identify the biomarkers for chronic hypersensitivity pneumonitis (CHP) and facilitate the precise gene therapy of CHP. Background: Chronic hypersensitivity pneumonitis (CHP) is an interstitial lung disease caused by hypersens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffd0df273a15f8727191eb6f1b2092b
https://pubmed.ncbi.nlm.nih.gov/33292121
https://pubmed.ncbi.nlm.nih.gov/33292121
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1868(11)
As the outward-most representation of life, phenotype is the fundamental basis with which humans understand life and disease. But with the advent of molecular and sequencing technique and research, a growing portion of science research focuses primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc36e81f2ec1ddd207a784bb67b2f868
https://pubmed.ncbi.nlm.nih.gov/32707349
https://pubmed.ncbi.nlm.nih.gov/32707349
Autor:
Tao Huang, Steven I. Wang
Publikováno v:
Methods in Molecular Biology ISBN: 9781071609033
The abundance of high-throughput data and technical refinements in graph theories have allowed network analysis to become an effective approach for various medical fields. This chapter introduces co-expression, Bayesian, and regression-based network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a15e3ddc93ffc4c98a9e46acd172f59
https://doi.org/10.1007/978-1-0716-0904-0_4
https://doi.org/10.1007/978-1-0716-0904-0_4
Autor:
Rebecca Boiarsky, Kevin S. Kapner, Daniel Zhao, Stephanie W. Cheng, Ananya D. Jambhale, Jimmy A. Guo, Patrick Z. Yu, Tyler Jacks, François Aguet, Daniel Y. Kim, Harshabad Singh, Hannah I. Hoffman, Brenton R. Paolella, Maryann Zhao, William L. Hwang, Steven I. Wang, Andrew J. Aguirre, John M. Krill-Burger, Westley W. Wu, Kristen E. Lowder, James M. McFarland, Tobiloba E. Oni, Aviv Regev, Gad Getz, Peter Chen, Scott P. Ginebaugh
Publikováno v:
Cancer Research. 81:PR-006
Targeted therapies for molecularly-defined subtypes have led to immense clinical benefit for many cancer types but have generally not been successful for pancreatic cancer. Given that the mainstay of treatment remains multi-agent chemotherapy with FO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd2b2ab6c72ca27c45082db78ae73eb
https://doi.org/10.1158/1538-7445.panca21-pr-006
https://doi.org/10.1158/1538-7445.panca21-pr-006
Autor:
Steven I. Wang, Hasan Mukhtar
Publikováno v:
Cancer Letters. 182:43-51
Green tea is an effective chemopreventive agent in animal tumor bioassays and some human cancers. Much of its cancer preventive effects appear to be mediated by its major polyphenolic constituent (-) epigallocatechin-3-gallate (EGCG). In order to bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b7c44401aa9f460feaceab2aa625e6
https://doi.org/10.1016/s0304-3835(02)00065-4
https://doi.org/10.1016/s0304-3835(02)00065-4
Publikováno v:
Genes, Chromosomes and Cancer. 24:322-327
The PTEN gene is involved in 10q23 deletions in several types of cancer, including glioma, melanoma, endometrial and prostate carcinomas. The PTEN gene product is a dual-specificity phosphatase with putative tumor suppressor function. Deletions and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc82ed559ab9d8053f005841b25a980e
https://doi.org/10.1002/(sici)1098-2264(199904)24:4<322::aid-gcc5>3.0.co
https://doi.org/10.1002/(sici)1098-2264(199904)24:4<322::aid-gcc5>3.0.co
Autor:
Michael Wigler, Ramon Parsons, Steven I. Wang, Charis Eng, Javor P. Stolarov, Michael P. Myers, Nicholas K. Tonks, Jing Li
Publikováno v:
Proceedings of the National Academy of Sciences. 94:9052-9057
Protein tyrosine phosphatases (PTPs) have long been thought to play a role in tumor suppression due to their ability to antagonize the growth promoting protein tyrosine kinases. Recently, a candidate tumor suppressor from 10q23, termed P-TEN, was iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4306816621a90a668f0145547d1cc5a5
https://doi.org/10.1073/pnas.94.17.9052
https://doi.org/10.1073/pnas.94.17.9052
Autor:
K. M. Call, Charis Eng, Shikha Bose, Ramon Parsons, Patricia L. M. Dahia, Jing Li, Deborah J. Marsh, Steven I. Wang, Z. Zheng, Danny Liaw, Hui C. Tsou, Monica Peacocke
Publikováno v:
Scopus-Elsevier
Cowden disease (CD) is an autosomal dominant cancer predisposition syndrome associated with an elevated risk for tumours of the breast, thyroid and skin1–2. Lhermitte-Duclos disease (LDD) cosegregates with a subset of CD families and is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8523448e04a875e4d6a50490922583
https://doi.org/10.1038/ng0597-64
https://doi.org/10.1038/ng0597-64
Autor:
Steven I. Wang, Ramon Parsons, Michael Ittmann, Beppino C. Giovanella, Linda Rodgers, Janusz Puc, Jing Li, Christa Miliaresis, B. Tycko, Richard W. McCombie, Michael Wigler, Sandra H. Bigner, Katrina Podsypanina, Clifford Yen, Hanina Hibshoosh, Shikha Bose, Danny Liaw
Publikováno v:
Science. 275:1943-1947
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN , that appears to be mutated at considerable frequency in human cancers. In preliminary screens, mutations of PTEN were dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5c659bb3cf968bd5b25a5edfd83dc7
https://doi.org/10.1126/science.275.5308.1943
https://doi.org/10.1126/science.275.5308.1943
Autor:
Steven I. Wang, Hasan Mukhtar
Publikováno v:
International Journal of Oncology.
An active internal ribosome entry sequence (IRES) that efficiently mediates cap (m7pppGN)-independent translation in human carcinoma cells could be an effective device for gene co-transduction in cancer gene therapy. In this study using the cytomegal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c644e366554bc279e17681d4163db54a
https://doi.org/10.3892/ijo.20.6.1269
https://doi.org/10.3892/ijo.20.6.1269