Zobrazeno 1 - 10 of 287 pro vyhledávání: '"Steven I, Sherman"'
1
Akademický článek
Challenges in the care of patients with RET-altered thyroid cancer: a multicountry mixed-methods study
Autor: Suzanne Murray, Vivek Subbiah, Steven I. Sherman, Sophie Péloquin, Anthony Sireci, Christian Grohé, Patrick Bubach, Patrice Lazure
Publikováno v: Thyroid Research, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background The discovery of driver oncogenes for thyroid carcinomas and the identification of genomically targeted therapies to inhibit those oncogenes have altered the treatment algorithm in thyroid cancer (TC), while germline testing for R
Externí odkaz: https://doaj.org/article/207fa35c8be54dfb9c44c1c5719d9e41
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2
Akademický článek
Challenges in diagnosis and biomarker testing for RET-altered lung and thyroid cancer care: an international mixed-method study
Autor: Patrice Lazure, Anthony Sireci, Vivek Subbiah, Suzanne Murray, Christian Grohé, Steven I. Sherman, Elizabeth Kelly, Patrick Bubach, Sophie Péloquin
Publikováno v: BMC Medical Education, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The introduction of new targeted therapies for RET-altered lung and thyroid cancers (LC/TC) has impacted pathologists’ practice by making genomic testing more relevant. Variations in health systems and treatment access result in
Externí odkaz: https://doaj.org/article/0594ca63905b472881c6251aa86d4766
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3
Akademický článek
Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies
Autor: Jessica Lee, Vivek Subbiah, Shuang Liu, Jason Roszik, David Hong, Funda Meric-Bernstam, John Heymach, Ramona Dadu, Kenneth Hess, Le Huang, Aparna Hegde, Alexander Y Andreev-Drakhlin, Maria Cabanillas, Mimi I Hu, Naifa L Busaidy, Steven I Sherman, Elizabeth G Grubbs, Siraj M Ali, Yasir Y Elamin, George R Simon, George R Blumenschein, Jr, Vassiliki A Papadimitrakopoulou
Publikováno v: ESMO Open, Vol 5, Iss 5 (2020)
Purpose The receptor tyrosine kinase rearranged during transfection (RET) can be oncogenically activated by gene fusions or point mutations. Multikinase inhibitors such as cabozantinib, lenvatinib and vandetanib have demonstrated activity in RET-depe
Externí odkaz: https://doaj.org/article/c90d0d405f934390885cdc8e42bce7c6
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6
Data from Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress–Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer
Autor: Robert F. Gagel, Steven I. Sherman, Gilbert J. Cote, Yue Lu, Ling Li, Krishna M. Sinha, Rozita Bagheri-Yarmand
Medullary thyroid carcinoma (MTC) originates from the C cells of the thyroid gland, which secrete calcitonin. Lymph node and distant metastases are frequently present at diagnosis. Activating mutations of RET, a driver oncogene in MTC that encodes a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::431c57696f3700e900c5b2a4c31ee5c3
https://doi.org/10.1158/1541-7786.c.6541137
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