Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Steven Hollis"'
With the introduction of climate action plans by many countries globally, the development of green technologies like electric vehicles and renewable infrastructure is expected to increase. These technologies are resource intensive, meaning we will re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1a474c9b6c66eb9a13cebaae9986ba
https://doi.org/10.5194/egusphere-egu23-16279
https://doi.org/10.5194/egusphere-egu23-16279
Autor:
Brian A. Lanman, Jennifer R. Allen, John G. Allen, Albert K. Amegadzie, Kate S. Ashton, Shon K. Booker, Jian Jeffrey Chen, Ning Chen, Michael J. Frohn, Guy Goodman, David J. Kopecky, Longbin Liu, Patricia Lopez, Jonathan D. Low, Vu Ma, Ana E. Minatti, Thomas T. Nguyen, Nobuko Nishimura, Alexander J. Pickrell, Anthony B. Reed, Youngsook Shin, Aaron C. Siegmund, Nuria A. Tamayo, Christopher M. Tegley, Mary C. Walton, Hui-Ling Wang, Ryan P. Wurz, May Xue, Kevin C. Yang, Pragathi Achanta, Michael D. Bartberger, Jude Canon, L. Steven Hollis, John D. McCarter, Christopher Mohr, Karen Rex, Anne Y. Saiki, Tisha San Miguel, Laurie P. Volak, Kevin H. Wang, Douglas A. Whittington, Stephan G. Zech, J. Russell Lipford, Victor J. Cee
Publikováno v:
Journal of Medicinal Chemistry. 63:52-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d131821132bab6ea5628a8639f9d9435
https://doi.org/10.1021/acs.jmedchem.9b01180
https://doi.org/10.1021/acs.jmedchem.9b01180
Autor:
Andrew M. Clausen, Karl B. Hansen, L. Steven Hollis, Melody L. Mak-Jurkauskas, Matthew M. Bio, Steven M. Mennen, Kelly A. Nadeau
Publikováno v:
Organic Process Research & Development. 19:884-891
A simple one-pot, two-step process for the conversion of 2-acylbenzoic acids to phthalazin-1(2H)-ones was developed. A robust process was required that delivered the final isolated solid with consistently low levels of residual hydrazine, for further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112ee808aa962011e1fa59c061d82a56
https://doi.org/10.1021/acs.oprd.5b00135
https://doi.org/10.1021/acs.oprd.5b00135
Autor:
Min-Hwa Jasmine Lin, Zhiyang Zhao, Jingzhou Liu, L. Steven Hollis, Adria E. Colletti, Yohannes Teffera, Deborah Choquette
Publikováno v:
Chemical Research in Toxicology. 23:1743-1752
Compound 1, (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine) is a potent, selective inhibitor of c-Met (mesenchymal-epithelial transition factor), a receptor tyrosine kinase that is oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f29b2a22234a1f810d35602747db846
https://doi.org/10.1021/tx100208k
https://doi.org/10.1021/tx100208k
Autor:
Harmange Jean-Christophe, Brian K. Albrecht, Alessandro Boezio, Jingzhou Liu, Zhiyang Zhao, L. Steven Hollis, Yohannes Teffera, Adria E. Colletti
Publikováno v:
Chemical Research in Toxicology. 21:2216-2222
AMG 458 {1-(2-hydroxy-2-methylpropyl)-N-[5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide} is a potent, selective inhibitor of c-Met, a receptor tyrosine kinase that is often deregulated in canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4594588c1a0890f82d0cca7beff6b3b
https://doi.org/10.1021/tx800307n
https://doi.org/10.1021/tx800307n
Autor:
L. Steven Hollis, Melody L. Mak-Jurkauskas, Matthew M. Bio, Karl B. Hansen, Kelly A. Nadeau, Andrew M. Clausen, Steven M. Mennen
Publikováno v:
ChemInform. 46
A simple one-pot, two-step process for the conversion of 2-acylbenzoic acids to phthalazin-1(2H)-ones was developed. A robust process was required that delivered the final isolated solid with consistently low levels of residual hydrazine, for further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5564cbf6b76b6da000409f6d8db47f8a
https://doi.org/10.1002/chin.201547178
https://doi.org/10.1002/chin.201547178
Autor:
Rodger F. Henry, Yu-Ming Pu, Weifeng Wang, L. Steven Hollis, Ian Marsden, Brian J. Kotecki, Seble Wagaw, Kenneth M. Engstrom
Publikováno v:
The Journal of Organic Chemistry. 71:5369-5372
A stereoselective synthesis of the hydroxyethylene dipeptide isostere 1 is described. The route employs a substrate-directed kinetic protonation of an alpha/gamma-substituted lactone to afford the desired stereochemistry. A method for converting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0760496819e9a76c5e14dbd8a54ded33
https://doi.org/10.1021/jo060737s
https://doi.org/10.1021/jo060737s
Autor:
Eric W. Kristensen, Eric J. Stoner, Gregory M. Brill, Alan Christesen, Casey Chun Zhou, Kent D. Stewart, Edmund D. Matayoshi, Steven J. Wittenberger, L. Steven Hollis, Ronald R. Rasmussen
Publikováno v:
Tetrahedron. 60:10611-10618
Oritavancin is a semi-synthetic glycopeptide antibiotic which is structurally related to vancomycin. When oritavancin bisphosphate is dried in vacuo with heat, a new compound forms. This new compound is stable only in the solid state and reverts to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2095a1b5434e682347c40cb775e4e17
https://doi.org/10.1016/j.tet.2004.09.019
https://doi.org/10.1016/j.tet.2004.09.019
Autor:
Laurie B. Schenkel, Min-Hwa Jasmine Lin, L. Steven Hollis, Zhiyang Zhao, Loren Berry, Daniel Waldon
Publikováno v:
Drug metabolism letters. 5(4)
AMG 900 is an orally available small molecule that is highly potent and selective as a pan-aurora kinase inhibitor. AMG 900 is currently undergoing phase 1 clinical evaluation in patients with advanced solid tumors. The metabolism of AMG 900 was inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f75b72c0d1242e9aefad88f94aba2a
https://pubmed.ncbi.nlm.nih.gov/22022868
https://pubmed.ncbi.nlm.nih.gov/22022868