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Akademický článek

Utilization of a cell‐penetrating peptide‐adaptor for delivery of human papillomavirus protein E2 into cervical cancer cells to arrest cell growth and promote cell death

Autor: Julia C. LeCher, Hope L. Didier, Robert L. Dickson, Lauren R. Slaughter, Juana C. Bejarano, Steven Ho, Scott J. Nowak, Carol A. Chrestensen, Jonathan L. McMurry

Publikováno v: Cancer Reports, Vol 6, Iss 5, Pp n/a-n/a (2023)

Abstract Background Human papillomavirus (HPV) is the causative agent of nearly all forms of cervical cancer, which can arise upon viral integration into the host genome and concurrent loss of viral regulatory gene E2. Gene‐based delivery approache

Externí odkaz: https://doaj.org/article/124f97a435f34ac59f4870fd8c16599a

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Akademický článek

Review of the Management of Obstructive Sleep Apnea and Pharmacological Symptom Management

Autor: Ladan Panahi, George Udeani, Steven Ho, Brett Knox, Jason Maille

Publikováno v: Medicina, Vol 57, Iss 11, p 1173 (2021)

Nearly a billion adults around the world are affected by a disease that is characterized by upper airway collapse while sleeping called obstructive sleep apnea or OSA. The progression and lasting effects of untreated OSA include an increased risk of

Externí odkaz: https://doaj.org/article/02393d22565a4149b9316269f0724fc8

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Akademický článek

Optimization of heavy chain and light chain signal peptides for high level expression of therapeutic antibodies in CHO cells.

Autor: Ryan Haryadi, Steven Ho, Yee Jiun Kok, Helen X Pu, Lu Zheng, Natasha A Pereira, Bin Li, Xuezhi Bi, Lin-Tang Goh, Yuansheng Yang, Zhiwei Song

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0116878 (2015)

Translocation of a nascent protein from the cytosol into the ER mediated by its signal peptide is a critical step in protein secretion. The aim of this work was to develop a platform technology to optimize the signal peptides for high level productio

Externí odkaz: https://doaj.org/article/39d0379794ba40608a271e6f893ea807

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