Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Steven Heshusius"'
Autor:
Steven Heshusius, Laura Grech, Nynke Gillemans, Rutger W. W. Brouwer, Xander T. den Dekker, Wilfred F. J. van IJcken, Benjamin Nota, Alex E. Felice, Thamar B. van Dijk, Marieke von Lindern, Joseph Borg, Emile van den Akker, Sjaak Philipsen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Haploinsufficiency for the erythroid-specific transcription factor KLF1 is associated with hereditary persistence of fetal hemoglobin (HPFH). Increased HbF ameliorates the symptoms of β-hemoglobinopathies and downregulation of KLF1 activity
Externí odkaz:
https://doaj.org/article/c05d644c68534f3f9075683f486793e0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that
Externí odkaz:
https://doaj.org/article/44382750c23b4f5ea8bf17014bcb5b20
Autor:
Steven Heshusius, Esther Heideveld, Patrick Burger, Marijke Thiel-Valkhof, Erica Sellink, Eszter Varga, Elina Ovchynnikova, Anna Visser, Joost H.A. Martens, Marieke von Lindern, Emile van den Akker
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3337-3350 (2019)
Abstract: Transfusion of donor-derived red blood cells (RBC) is the most common form of cellular therapy. Donor availability and the potential risk of alloimmunization and other transfusion-related complications may, however, limit the availability o
Externí odkaz:
https://doaj.org/article/9924b06b29a44b248baef47e7fef9ab2
Autor:
Anne Korporaal, Nynke Gillemans, Steven Heshusius, Ileana Cantú, Emile van den Akker, Thamar B. van Dijk, Marieke von Lindern, Sjaak Philipsen
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia
Externí odkaz:
https://doaj.org/article/be271501667a4190b60d587d61ed3c5a
Autor:
Ileana Cantú, Harmen J G van de Werken, Nynke Gillemans, Ralph Stadhouders, Steven Heshusius, Alex Maas, Fatemehsadat Esteghamat, Zeliha Ozgur, Wilfred F J van IJcken, Frank Grosveld, Marieke von Lindern, Sjaak Philipsen, Thamar B van Dijk
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >140 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://doaj.org/article/a036d268167f4395a300831947ef3990
Autor:
Marieke von Lindern, Elina Ovchynnikova, Marijke Thiel-Valkhof, Emile van den Akker, Eszter Varga, Erica Sellink, Joost H.A. Martens, Patrick Burger, Steven Heshusius, Anna Visser, Esther Heideveld
Transfusion of donor-derived red blood cells is the most common form of cellular therapy. Donor availability and the potential risk of alloimmunization and other transfusion-related complications may, however, limit the availability of transfusion un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c4a5618ea15a604b69250ed98adce2
Autor:
Steven Heshusius, Frank Grosveld, Ralph Stadhouders, Marieke von Lindern, Sjaak Philipsen, Alex Maas, Nynke Gillemans, Wilfred F. J. van IJcken, Harmen J.G. van de Werken, Thamar B. van Dijk, Zeliha Ozgur, Fatemehsadat Esteghamat, Ileana Cantú
Publikováno v:
PLoS ONE
PLoS ONE, 14(3):e0208659. Public Library of Science
PLoS One (online), 14(3):e0208659. Public Library of Science
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
PLoS ONE, 14(3):e0208659. Public Library of Science
PLoS One (online), 14(3):e0208659. Public Library of Science
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >140 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492dd1d517b628ed98595503933f7fd9
http://europepmc.org/articles/PMC6438607
http://europepmc.org/articles/PMC6438607
Autor:
Marieke von Lindern, Ralph Stadhouders, Steven Heshusius, Frank Grosveld, Sjaak Philipsen, Wilfred F. J. van IJcken, Alex Maas, Zeliha Ozgur, Thamar B. van Dijk, Harmen J.G. van de Werken, Ileana Cantú, Nynke Gillemans
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >65 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eaadd8624adc3d435bffacfe0a38f1
Autor:
M. von Lindern, Patrick Burger, E. van den Akker, M. Hansen, Tatjana Wüst, Eszter Varga, Steven Heshusius, Menno Hofman
Publikováno v:
HemaSphere. 3:562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::324a3d7acaa903f5aa0266933e8a540c
https://doi.org/10.1097/01.hs9.0000563220.34146.5d
https://doi.org/10.1097/01.hs9.0000563220.34146.5d
Autor:
Steven Heshusius, E. Sellink, Emile van den Akker, Esther Heideveld, Patrick Burger, Marten Hansen, Tatjana Wüst, M. Thiel, Eszter Varga, Marieke von Lindern, J. Eernstmans
Publikováno v:
Cytotherapy. 19:S49-S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753fae0cf36b51e83f54f1ac76d11ba6
https://doi.org/10.1016/j.jcyt.2017.02.110
https://doi.org/10.1016/j.jcyt.2017.02.110