Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Steven Hamley"'
Autor:
Clinton R. Bruce, Steven Hamley, Teddy Ang, Kirsten F. Howlett, Christopher S. Shaw, Greg M. Kowalski
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101281- (2021)
Objective: The glucose tolerance test (GTT) is widely used in human and animal biomedical and pharmaceutical research. Despite its prevalent use, particularly in mouse metabolic phenotyping, to the best of our knowledge we are not aware of any studie
Externí odkaz:
https://doaj.org/article/3a86daa6f2bb4e6995d2993e6e6f391a
Autor:
Ahrathy Selathurai, Greg M. Kowalski, Shaun A. Mason, Damien L. Callahan, Victoria C. Foletta, Paul A. Della Gatta, Angus Lindsay, Steven Hamley, Gunveen Kaur, Annie R. Curtis, Micah L. Burch, Teddy Ang, Sean L. McGee, Clinton R. Bruce
Publikováno v:
Molecular Metabolism, Vol 27, Iss , Pp 33-46 (2019)
Objective: Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mito
Externí odkaz:
https://doaj.org/article/014e06075bd9459593a0edd456e20e9c
Autor:
Steven Hamley
Publikováno v:
Nutrition Journal, Vol 16, Iss 1, Pp 1-16 (2017)
Abstract Background A cornerstone of conventional dietary advice is the recommendation to replace saturated fatty acids (SFA) with mostly n-6 polyunsaturated fatty acids (PUFA) to reduce the risk of coronary heart disease (CHD). Many clinical trials
Externí odkaz:
https://doaj.org/article/00005675f2754182b0bdd8c774f5738c
Autor:
Steven Hamley, Teddy Ang, Clinton R. Bruce, Christopher S. Shaw, Kirsten F. Howlett, Greg M. Kowalski
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 53, Iss, Pp 101281-(2021)
Molecular Metabolism, Vol 53, Iss, Pp 101281-(2021)
Objective The glucose tolerance test (GTT) is widely used in human and animal biomedical and pharmaceutical research. Despite its prevalent use, particularly in mouse metabolic phenotyping, to the best of our knowledge we are not aware of any studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13b23f47c30df3dcf3b627e5b63df2e
http://europepmc.org/articles/PMC8313600
http://europepmc.org/articles/PMC8313600
Autor:
Teddy Ang, Ahrathy Selathurai, Angus Lindsay, Victoria C. Foletta, Gunveen Kaur, Clinton R. Bruce, Sean L. McGee, Micah L Burch, Shaun A. Mason, Steven Hamley, Paul A. Della Gatta, Damien L. Callahan, Grzegorz M Kowalski, Annie R Curtis
Publikováno v:
Molecular Metabolism, Vol 27, Iss, Pp 33-46 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d48d5b907b2317df0cc50f55e04300
http://www.sciencedirect.com/science/article/pii/S2212877819302698
http://www.sciencedirect.com/science/article/pii/S2212877819302698
Publikováno v:
Diabetes. 66:2400-2406
Insulin clamp studies have shown that the suppressive actions of insulin on endogenous glucose production (EGP) are markedly more sensitive than for stimulating glucose disposal (Rd). However, clamp conditions do not adequately mimic postprandial phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b726696b140f0c7a090ddff405956780
https://doi.org/10.2337/db17-0433
https://doi.org/10.2337/db17-0433
Autor:
Adam Alexander T. Smith, Peter J. Meikle, Maria G Morales-Scholz, Natalie A. Mellet, Clinton R. Bruce, Kevin Huynh, Danielle Kloosterman, Habtamu Bedimo Beyene, Michelle Cinel, Christopher S. Shaw, Steven Hamley, Dianna J. Magliano, Greg M. Kowalski, Corey Giles, Kirsten F. Howlett
Publikováno v:
The Journal of clinical endocrinology and metabolism. 105(3)
Context Insulin resistance (IR) remains a global health challenge. Lipidomics offers an opportunity to identify biomarkers and better understand mechanisms of IR associated with abnormal lipid metabolism. Objective The objective of this article is to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e285dc08d65e2cae94a9a4a9a2baa1
https://pubmed.ncbi.nlm.nih.gov/32016362
https://pubmed.ncbi.nlm.nih.gov/32016362
Autor:
Joachim Kloehn, Malcolm J. McConville, Ahrathy Selathurai, Stephanie A.M. Bayol, Séverine Lamon, Robert S. Lee-Young, Matthew J. Watt, Grzegorz M Kowalski, Micah L Burch, Clinton R. Bruce, Steven Hamley
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1851:210-219
Hepatic insulin resistance is a major risk factor for the development of type 2 diabetes and is associated with the accumulation of lipids, including diacylglycerol (DAG), triacylglycerols (TAG) and ceramide. There is evidence that enzymes involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803cf39e4e6a9be4431c52fbf4e4acaf
https://doi.org/10.1016/j.bbalip.2014.12.002
https://doi.org/10.1016/j.bbalip.2014.12.002
Autor:
David P De Souza, Dedreia Tull, Brunda Nijagal, Steven Hamley, Malcolm J. McConville, Clinton R. Bruce, Ahrathy Selathurai, Greg M. Kowalski, Sean O'Callaghan, Joachim Kloehn
Publikováno v:
Scientific Reports
In humans, low-energy diets rapidly reduce hepatic fat and improve/normalise glycemic control. Due to difficulties in obtaining human liver, little is known about changes to the lipid species and pathway fluxes that occur under these conditions. Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec08b956e98cb127d045503c22809952
Autor:
David P De Souza, Dedreia Tull, Greg M. Kowalski, Clinton R. Bruce, Steve Risis, Joachim Kloehn, Micah L Burch, Malcolm J. McConville, Ahrathy Selathurai, Sean O'Callaghan, Steven Hamley, Robert S. Lee-Young
Publikováno v:
Biochemical and biophysical research communications. 463(4)
Rationale Cardiac metabolism is thought to be altered in insulin resistance and type 2 diabetes (T2D). Our understanding of the regulation of cardiac substrate metabolism and insulin sensitivity has largely been derived from ex vivo preparations whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848cee618f2b12cd0cd1c3fa62d82e03
https://pubmed.ncbi.nlm.nih.gov/26086096
https://pubmed.ncbi.nlm.nih.gov/26086096