Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Steven H. L. Verhelst"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Barniol-Xicota and Verhelst investigate the usefulness of different maleic acid-based copolymers (xMAs) to solubilize membrane proteins within native-like lipid environments. They use bacterial and mammalian cell lines to study different polymer solu
Externí odkaz:
https://doaj.org/article/e04abed1f80245d8b1e11956b1dbd7d6
Autor:
Marine Houdou, Nathalie Jacobs, Jonathan Coene, Mujahid Azfar, Roeland Vanhoutte, Chris Van den Haute, Jan Eggermont, Veronique Daniëls, Steven H. L. Verhelst, Peter Vangheluwe
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 337 (2023)
Cells acquire polyamines putrescine (PUT), spermidine (SPD) and spermine (SPM) via the complementary actions of polyamine uptake and synthesis pathways. The endosomal P5B-type ATPases ATP13A2 and ATP13A3 emerge as major determinants of mammalian poly
Externí odkaz:
https://doaj.org/article/f58ce20d84b2469ebda98b8c2723a99b
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/c1896e33ea22491bb595ad959ade00d5
Autor:
Ruzanna Mnatsakanyan, Stavroula Markoutsa, Kim Walbrunn, Andreas Roos, Steven H. L. Verhelst, René P. Zahedi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Reversible cysteine modifications play important roles in cellular redox signaling. Here, the authors develop a chemical proteomics strategy that enables the quantitative analysis of endogenous cysteine nitrosylation sites and their dynamic regulatio
Externí odkaz:
https://doaj.org/article/a46b2f4d4dac4cac9faa09918943bfac
Publikováno v:
Molecules, Vol 25, Iss 24, p 5994 (2020)
Activity-based protein profiling (ABPP) is a powerful technique to label and detect active enzyme species within cell lysates, cells, or whole animals. In the last two decades, a wide variety of applications and experimental read-out techniques have
Externí odkaz:
https://doaj.org/article/7b6c301abeb249cb973b45ea33423dd9
Autor:
Tim Van Kersavond, Raphael Konopatzki, Suravi Chakrabarty, Bernhard Blank-Landeshammer, Albert Sickmann, Steven H. L. Verhelst
Publikováno v:
Molecules, Vol 24, Iss 1, p 206 (2019)
Chemical probes that covalently interact with proteases have found increasing use for the study of protease function and localization. The design and synthesis of such probes is still a bottleneck, as the strategies to target different families are h
Externí odkaz:
https://doaj.org/article/27b1de214ab34546971edbd631c8c605
Publikováno v:
Molecules, Vol 18, Iss 10, Pp 12599-12608 (2013)
Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labelin
Externí odkaz:
https://doaj.org/article/0c601f732bae4e31af29dcbdc2abeb5c
Autor:
Suyuan Chen, Chunguang Liang, Hongli Li, Weimeng Yu, Michaela Prothiwa, Dominik Kopczynski, Stefan Loroch, Marc Fransen, Steven H. L. Verhelst
Publikováno v:
ACS Chemical Biology. 18:686-692
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure–Activity Relationship
Autor:
Jan Pascal Kahler, Vincenzo Davide Aloi, Julia Miedes Aliaga, Sara Kerselaers, Thomas Voets, Joris Vriens, Steven H. L. Verhelst, Marta Barniol-Xicota
Publikováno v:
ACS Chemical Biology. 18:456-464
Autor:
Bing-Yu Li, Kexin Su, Luc Van Meervelt, Steven H. L. Verhelst, Ermal Ismalaj, Wim M. De Borggraeve, Joachim Demaerel
Publikováno v:
Angewandte Chemie International Edition.