Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Steven H. Graham"'
Autor:
Hao Liu, Wenjin Li, Muzamil Ahmad, Tricia M. Miller, Marie E. Rose, Samuel M. Poloyac, Guy Uechi, Manimalha Balasubramani, Robert W. Hickey, Steven H. Graham
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 318-328 (2011)
Cyclopentenone prostaglandins (CyPGs), such as 15-deoxy-Δ12,14 -prostaglandin J2 (15d-PGJ2), are active prostaglandin metabolites exerting a variety of biological effects that may be important in the pathogenesis of neurological diseases. Ubiquitin-
Externí odkaz:
https://doaj.org/article/15922a289b16490b87fdd7cf37929422
Autor:
Daniel P. Reay, Marie E. Rose, Hao Liu, Jie Ma, Steven H. Graham, Jeremy Henchir, Zhiping Mi, Xiecheng Ma, C. Edward Dixon
Publikováno v:
Neuroscience
Ubiquitin carboxy terminal hydrolase L1 (UCHL1) is a protein highly expressed in neurons that may play important roles in the ubiquitin proteasome pathway (UPP) in neurons, axonal integrity, and motor function after traumatic brain injury (TBI). Bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e845a0672092eb26aee030337a967c
https://doi.org/10.1016/j.neuroscience.2021.09.001
https://doi.org/10.1016/j.neuroscience.2021.09.001
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178049 (2017)
Many mechanisms or pathways are involved in secondary post-traumatic brain injury, such as the ubiquitin-proteasome pathway (UPP), axonal degeneration and neuronal cell apoptosis. UCH-L1 is a protein that is expressed in high levels in neurons and ma
Externí odkaz:
https://doaj.org/article/e4b39021ddbd4211ab354bbb034d26eb
Autor:
Zhiping Mi, Steven H. Graham
Publikováno v:
Ageing Research Reviews. 86:101856
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f2fb22411692fba8cedc7d83b20e04
https://doi.org/10.1016/j.arr.2023.101856
https://doi.org/10.1016/j.arr.2023.101856
Autor:
Samuel M. Poloyac, Patrick M. Kochanek, Shaun W. Carlson, Milos D. Ikonomovic, Edwin K. Jackson, Ava M. Puccio, Amery Treble-Barna, Corina O. Bondi, Michael J. Bell, Alicia K. Au, Ruchira M. Jha, Hülya Bayır, D. Lansing Taylor, Dennis W. Simon, Yvette P. Conley, Jonathan Elmer, Valerian E. Kagan, Stephen R. Wisniewski, Lori Shutter, Philip E. Empey, Robert S. B. Clark, Anthony E. Kline, Amy K. Wagner, Christopher M. Horvat, Travis C. Jackson, Steven H. Graham, C. Edward Dixon, Andrew M. Stern, David O. Okonkwo
Publikováno v:
J Neurotrauma
New neuroprotective therapies for severe traumatic brain injury (TBI) have not translated from pre-clinical to clinical success. Numerous explanations have been suggested in both the pre-clinical and clinical arenas. Coverage of TBI in the lay press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd3b52854514273c852375f13bf9cdd
https://doi.org/10.1089/neu.2018.6203
https://doi.org/10.1089/neu.2018.6203
Autor:
Steven H Graham
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 6, Pp 908-909 (2016)
Externí odkaz:
https://doaj.org/article/40cb78554cd04a428df26b3d2d5273a5
Publikováno v:
Neuropharmacology. 145:160-176
Traumatic brain injury (TBI) is a risk factor for development of chronic neurodegenerative disorders later in life. This review summarizes the current knowledge and concepts regarding the connection between long-term consequences of TBI and aging-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5baa9e07b44a4e21c3d3c548fb03c37
https://doi.org/10.1016/j.neuropharm.2018.06.021
https://doi.org/10.1016/j.neuropharm.2018.06.021
Autor:
Fenghua Chen, Wenjin Li, Steven H. Graham, Daniel P. Reay, Feng Zhang, German Barrionuevo, N. V. Povysheva, Marie E. Rose, Hao Liu, Zhiping Mi, Joseph S. Banton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Many neuroprotective strategies have failed to translate to clinical trials, perhaps because of a failure to preserve white matter function. Ubiquitin C-terminal hydrolase L1 (UCHL1), a neuron-specific protein essential for axonal functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f5f621bb76094b0d0f6067c20da2f5
http://europepmc.org/articles/PMC6410860
http://europepmc.org/articles/PMC6410860
Autor:
Fenghua Chen, Steven H. Graham, Lihong Han, Zhongfang Weng, Guodong Cao, Qinghai Xia, Catherine Cao, Jian Xiao, Rehana K. Leak
Publikováno v:
Transl Stroke Res
Our previous study indicated that nicotinamide phosphoribosyltransferase (NAMPT) is released from cells and might be an important extracellular neuroprotective factor in brain ischemia. Here we tested whether NAMPT protects against ischemic brain inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35e96a29d9e15eea78709207b2d0779
https://europepmc.org/articles/PMC6713626/
https://europepmc.org/articles/PMC6713626/
Autor:
Hao Liu, Marie E. Rose, Xiecheng Ma, Daniel P. Reay, Jie Ma, Jeremy Henchir, Zhiping Mi, Steven H. Graham, C. Edward Dixon
Publikováno v:
Exp Neurol
Ubiquitin (Ub) C-terminal hydrolase L1 (UCHL1) is a multifunctional protein that is expressed in neurons throughout brain at high levels. UCHL1 deletion is associated with axonal degeneration, progressive sensory motor ataxia, and premature death in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c02ff1cc0165d219e20114c1fdea995
https://doi.org/10.1016/j.expneurol.2020.113524
https://doi.org/10.1016/j.expneurol.2020.113524