Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven H. Bass"'
Autor:
Kuoting Wu, Clifford Wong, Margaret Neighbors, Erik E. Karrer, Yasuyuki Higashi, Madan M. Paidhungat, Steven J. Chapin, Steven H. Bass, Bruce H. Devens, Shinsuke Oshima, Margaret Reed, Brent R. Larsen, Yonghong Chen, Francisco A. Anderson, Marc Whitlow, Rujuta A. Bam, Sridhar Viswanathan, Rong A. Fan, Qian Zhang
Publikováno v:
Protein Engineering Design and Selection. 29:159-167
The CTLA4-Ig therapeutics abatacept and belatacept inhibit CD28-mediated T cell activation by binding CD80 (B7-1) and CD86 (B7-2) co-stimulatory ligands. Both compounds preferentially bind CD80, yet CD86 has been implicated as the dominant co-stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16578a205d00bb45328a4431b02b5c0
https://doi.org/10.1093/protein/gzw002
https://doi.org/10.1093/protein/gzw002
Publikováno v:
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents. 2:228-236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d62bece0ef0c46378a25c2b6fd158dbf
https://doi.org/10.2174/1568014033483716
https://doi.org/10.2174/1568014033483716
Publikováno v:
Proceedings of the National Academy of Sciences. 88:4498-4502
A mutational strategy is presented that allowed us to identify hormone-binding determinants in the extracellular portion of the human growth hormone receptor (hGHbp), a 238-residue protein with sequence homology to a number of cytokine receptors. By
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81088939770c42714b531020e2675b3a
https://doi.org/10.1073/pnas.88.10.4498
https://doi.org/10.1073/pnas.88.10.4498
Publikováno v:
Proteins: Structure, Function, and Genetics. 8:309-314
Human growth hormone (hGH), a 191 residue protein containing two disulfide bonds, was fused to the carboxyl-terminal domain of the gene III protein, a minor coat protein exposed at one end of the filamentous phage M13. The gene fusion was cloned into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b96cda02110833f60a55263c730de4
https://doi.org/10.1002/prot.340080405
https://doi.org/10.1002/prot.340080405
Autor:
Steven H. Bass, Daniel G. Yansura
Publikováno v:
Molecular biotechnology. 16(3)
The Escherichia coli tryptophan (trp) promoter has been used extensively for the high level production of proteins on a small and large scale. This regulated promoter is readily available, relatively easy to turn on, and can be used in essentially an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00492cf14d0fa54672244fcfe9892c6c
https://pubmed.ncbi.nlm.nih.gov/11252809
https://pubmed.ncbi.nlm.nih.gov/11252809
Autor:
James A. Wells, Michael G. Mulkerrin, Germaine Fuh, Steven H. Bass, Henry B. Lowman, Abraham M. DeVos, Mark Ultsch, Brian C. Cunningham
High-resolution mutational and structural analyses of purified components have revealed a great deal about the molecular basis for growth hormone action. The structural and functional aspects of the interactions between hGH and its receptors have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8893ee6151b3d4e4a9b963e946ddbf5
https://doi.org/10.1016/b978-0-12-571148-7.50013-0
https://doi.org/10.1016/b978-0-12-571148-7.50013-0
Publikováno v:
Biochemistry. 30(45)
Variants of human growth hormone (hGH) with increased affinity and specificity for the hGH receptor were isolated using an improved phage display system. Nearly one million random mutants of hGH were generated at 12 sites previously shown to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1132ae9e61e120195cacfb27e4ebc577
https://pubmed.ncbi.nlm.nih.gov/1932005
https://pubmed.ncbi.nlm.nih.gov/1932005
Autor:
Steven H. Bass, James A. Wells
Publikováno v:
New England Journal of Medicine. 322:854-855
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7843668c629c9adb35da04c96daf4a
https://doi.org/10.1056/nejm199003223221218
https://doi.org/10.1056/nejm199003223221218
Publikováno v:
Blood. 60:924-929
We evaluated neutrophil adhesive function in patients undergoing chronic hemodialysis using either prostacyclin or heparin as antithrombotic agents. Patients underwent successive hemodialyses with prostacyclin (4 ng/kg/min) and heparin. There were no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b7b1ec48f8650e20222737abd7263c
https://doi.org/10.1182/blood.v60.4.924.924
https://doi.org/10.1182/blood.v60.4.924.924