Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Steven H Nye"'
Autor:
Michael Bittner, Pamela A. Hershberger, James G. Yarger, Wei Xu, Steven H. Nye, Erin K. Shanle, Robert E. Babine
Publikováno v:
Journal of Molecular Endocrinology
Ligand structure can affect the activation of nuclear receptors, such as estrogen receptors (ERs), and their control of signaling pathways for cellular responses including death and differentiation. We hypothesized that distinct biological functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac4d14b30e8e2c40b50d074fffca633
http://europepmc.org/articles/PMC3535725
http://europepmc.org/articles/PMC3535725
Autor:
Dale J. Kempf, Annette J. Dahly-Vernon, Yi Yang, Howard J. Jacob, Jie Lai-Zhang, Yvette A. Harrington, Kennan C. Marsh, Steven H Nye, Jeffrey F. Waring, Eric A.G. Blomme, Richard J. Roman, Darin L. Evans
Publikováno v:
The Veterinary Journal. 185:75-82
Ritonavir (RTV) and other protease inhibitors (PIs) used for the treatment of human immunodeficiency virus (HIV) infection are associated with elevated serum triglycerides (TG) and cholesterol in some patients. A rat strain (Sprague–Dawley or SD) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb161752767a608b06b207ed4161cc09
https://doi.org/10.1016/j.tvjl.2010.04.017
https://doi.org/10.1016/j.tvjl.2010.04.017
Publikováno v:
Behavior Genetics. 40:85-92
The isolation of genes influencing long-term memory is critical for an understanding of learning at the molecular level. Recently, chromosomal substitution rat strains, known as consomics, have been developed. Here we report the results of the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464db68ebe94a232ff3ad5b033bb9b5f
https://doi.org/10.1007/s10519-009-9297-5
https://doi.org/10.1007/s10519-009-9297-5
Autor:
Howard J. Jacob, D. L. Evans, Steven H Nye, Richard J. Roman, J. A. O'Connor, A. L. Wittenburg
Publikováno v:
The Pharmacogenomics Journal. 8:16-22
We examined whether survival of different rat strains administered anthrax lethal toxin is genetically determined. A reproducible test population of first filial generation hybrid rats was bred based on the susceptibility of progenitors to anthrax le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d20014d0be254aabc5a8a3a76a608c2
https://doi.org/10.1038/sj.tpj.6500448
https://doi.org/10.1038/sj.tpj.6500448
Autor:
Mark J. Evans, John P. Mueller, Steven H. Nye, Russell P. Rother, Stephen P. Squinto, Allen J. Norin, James A. Wilkins, Galo A Grijalva, Dennis W. Wolff, Denise M Therrien, Scott A. Rollins
Publikováno v:
Molecular Immunology. 32:1183-1195
Complement activation has been implicated in the pathogenesis of several human diseases. Recently, a monoclonal antibody, (N19-8) that recognizes the human complement protein C5 has been shown to effectively block the cleavage of C5 into C5a and C5b,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8880708a39db086a0ba15f383dfe39c9
https://doi.org/10.1016/0161-5890(95)00099-2
https://doi.org/10.1016/0161-5890(95)00099-2
Autor:
John P. Mueller, Clara M. Pelfrey, Steven H. Nye, Jeffrey J. Burkwit, Rhonda R. Voskuhl, Michael J. Lenardo
Publikováno v:
Molecular Immunology. 32:1131-1141
We have designed and expressed in bacteria a recombinant fetal form of human myelin basic protein (21.5 kDa isoform; rhMBP21.5), a candidate autoantigen in multiple sclerosis. An exon 2 insertion, carboxy-terminal histidine tag and preferred bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a955b4dfac48becee8c81af04ea4e1
https://doi.org/10.1016/0161-5890(95)00066-6
https://doi.org/10.1016/0161-5890(95)00066-6
Autor:
Steven H. Nye, Trevor Stitt, Stephen P. Squinto, M J Macchi, David J. Glass, George D. Yancopoulos, N S Lindsay, Nancy Y. Ip, Petros A. Hantzopoulos
Publikováno v:
Molecular Biology of the Cell. 3:677-686
The same receptor tyrosine kinase (RTK) can mediate strikingly different biological responses in a fibroblast as opposed to a neuron. We have compared the rapidly induced tyrosine phosphorylations mediated by various RTKs in both NIH3T3 fibroblasts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21689daf22677ac624c9662e4059d877
https://doi.org/10.1091/mbc.3.6.677
https://doi.org/10.1091/mbc.3.6.677
Autor:
Neil Stahl, Steven H. Nye, Yanping Li, Susan J. Birren, Nancy Y. Ip, Tert G. Boulton, David J. Anderson, Tadamitus Kishimoto, Tetsuya Taga, Samuel Davis, Kiyoshi Yasukawa, George D. Yancopoulos
Publikováno v:
Cell. 69:1121-1132
Ciliary neurotrophic factor (CNTF) has a variety of actions within the nervous system. While some of the actions of leukemia inhibitory factor (LIF) on neurons resemble those of CNTF, LIF also has broad actions outside of the nervous system that in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303d665a3a6f1bf09f641ecce531eb0e
https://doi.org/10.1016/0092-8674(92)90634-o
https://doi.org/10.1016/0092-8674(92)90634-o
Autor:
Lee O. Villatoro, Rodney A. Swain, Steven H. Nye, Megan L. Hensel, Abigail L. Kerr, Todd C. Peterson
Publikováno v:
Behavior genetics. 40(1)
The present study was conducted in an effort to evaluate whether chromosomal substitution can repair impaired exploration learning and memory. It has previously been observed that Dahl salt-sensitive (SS) rodents exhibit impaired cognitive function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6fe6c2db7c5ee4c30a7b1741200c70
https://pubmed.ncbi.nlm.nih.gov/19763809
https://pubmed.ncbi.nlm.nih.gov/19763809
Autor:
George D. Yancopoulos, Steven H. Nye, Mary J. Macchi, Mitchell Goldfarb, Stephen P. Squinto, Petros A. Hantzopoulos, David J. Glass
Publikováno v:
Cell. 66:405-413
The neurotrophins (nerve growth factor [NGF], brain-derived neurotrophic factor [BDNF], neurotrophin-3 [NT-3], and neurotrophin-4 [NT-4] ) have been defined by their ability to support neuronal survival. These factors utilize the Trk family of recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2589823f1687952b42f3923dc6a8cc60
https://doi.org/10.1016/0092-8674(91)90629-d
https://doi.org/10.1016/0092-8674(91)90629-d