Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Steven H Aggen"'
Autor:
Takeshi Otowa, Brion S Maher, Steven H Aggen, Joseph L McClay, Edwin J van den Oord, John M Hettema
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112559 (2014)
Anxiety disorders (ADs) are common mental disorders caused by a combination of genetic and environmental factors. Since ADs are highly comorbid with each other, partially due to shared genetic basis, studying AD phenotypes in a coordinated manner may
Externí odkaz:
https://doaj.org/article/a9b64d9c145a4810a15629c3483e54a1
Autor:
Timothy P York, Jenni Brumelle, Jane Juusola, Kenneth S Kendler, Lindon J Eaves, Ananda B Amstadter, Steven H Aggen, Kimberly H Jones, Andrea Ferreira-Gonzalez, Colleen Jackson-Cook
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55337 (2013)
Childhood sexual abuse (CSA) is a traumatic life event associated with an increased lifetime risk for psychopathology/morbidity. The long-term biological consequences of CSA-elicited stress on chromosomal stability in adults are unknown. The primary
Externí odkaz:
https://doaj.org/article/c9c5d6617a63423f8e4ab88f28541ca2
Autor:
Jingchun Chen, Darlene H Brunzell, Kia Jackson, Andrew van der Vaart, Jennie Z Ma, Thomas J Payne, Richard Sherva, Lindsay A Farrer, Pablo Gejman, Douglas F Levinson, Peter Holmans, Steven H Aggen, Imad Damaj, Po-Hsiu Kuo, Bradley T Webb, Raymond Anton, Henry R Kranzler, Joel Gelernter, Ming D Li, Kenneth S Kendler, Xiangning Chen
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28790 (2011)
Individuals with schizophrenia tend to be heavy smokers and are at high risk for tobacco dependence. However, the nature of the comorbidity is not entirely clear. We previously reported evidence for association of schizophrenia with SNPs and SNP hapl
Externí odkaz:
https://doaj.org/article/a85d9180dfb441f5b180e0674d21d02b
Autor:
Nancy L Saccone, Robert C Culverhouse, Tae-Hwi Schwantes-An, Dale S Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko, Xiangyang Kong, Maria Teresa Landi, Jennie Z Ma, Susan E Short, Sarah H Stephens, Victoria L Stevens, Lingwei Sun, Yufei Wang, Angela S Wenzlaff, Steven H Aggen, Naomi Breslau, Peter Broderick, Nilanjan Chatterjee, Jingchun Chen, Andrew C Heath, Markku Heliövaara, Nicole R Hoft, David J Hunter, Majken K Jensen, Nicholas G Martin, Grant W Montgomery, Tianhua Niu, Thomas J Payne, Leena Peltonen, Michele L Pergadia, John P Rice, Richard Sherva, Margaret R Spitz, Juzhong Sun, Jen C Wang, Robert B Weiss, William Wheeler, Stephanie H Witt, Bao-Zhu Yang, Neil E Caporaso, Marissa A Ehringer, Tim Eisen, Susan M Gapstur, Joel Gelernter, Richard Houlston, Jaakko Kaprio, Kenneth S Kendler, Peter Kraft, Mark F Leppert, Ming D Li, Pamela A F Madden, Markus M Nöthen, Sreekumar Pillai, Marcella Rietschel, Dan Rujescu, Ann Schwartz, Christopher I Amos, Laura J Bierut
Publikováno v:
PLoS Genetics, Vol 6, Iss 8, p e1001053 (2010)
Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit genes.
Externí odkaz:
https://doaj.org/article/ec22c1d8d2fc40a4a6583be408b4a69a
Autor:
Kenneth S. Kendler, Steven H. Aggen
Publikováno v:
Psychological Medicine. :1-8
Background Are genetic risk factors for current depressive symptoms good proxies for genetic risk factors for syndromal major depression (MD)? Methods In over 9000 twins from the population-based Virginia Adult Twin Study of Psychiatric and Substance
Publikováno v:
Journal of Psychopathology and Clinical Science. 132:396-408
Autor:
Mallory Stephenson, Steven H Aggen, Kathryn Polak, Dace S Svikis, Kenneth S Kendler, Alexis C Edwards
Publikováno v:
Alcohol Alcohol
Aim The present study examined patterns and correlates of polysubstance use among individuals with severe alcohol use disorder (AUD). Methods Participants were 2785 individuals (63% female; mean age = 43 years, range = 18–78 years) from the Genes,
Autor:
Sheida Moradi, Mohammad Reza Falsafinejad, Ali Delavar, Vahid Rezaeitabar, Ahmad Borj'ali, Steven H. Aggen, Kenneth S. Kendler
Publikováno v:
Psychological medicine.
Background Major depressive disorder (MDD) is one of the growing human mental health challenges facing the global health care system. In this study, the structural connectivity between symptoms of MDD is explored using two different network modeling
Autor:
Kenneth S. Kendler, Mackenzie J. Lind, Kaitlin E. Bountress, Terrell A. Hicks, Ananda B. Amstadter, Steven H. Aggen, Christina M. Sheerin
Publikováno v:
Subst Use Misuse
BACKGROUND: Stressful life events (SLEs) are a risk factor for alcohol use problems, and there is a need for identification of factors that may offset this risk. Resilience is uniquely, inversely associated with alcohol use, but there remains a deart
Autor:
Sacha Epskamp, Han L.J. van der Maas, Roseann E. Peterson, Hanna M. van Loo, Steven H. Aggen, Kenneth S. Kendler
Publikováno v:
Addictive Behaviors, 129:107252. Elsevier
Addictive Behaviors, 129:107252. PERGAMON-ELSEVIER SCIENCE LTD
Addictive Behaviors, 129:107252. PERGAMON-ELSEVIER SCIENCE LTD
Many people across the world use potentially addictive legal and illegal substances, but evidence suggests that not all use leads to heavy use and dependence, as some substances are used moderately for long periods of time. Here, we empirically exami