Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Steven Geis"'
Publikováno v:
In Clinical Therapeutics 2001 23(2):213-227
Publikováno v:
In Clinical Therapeutics 1999 21(6):992-1003
Autor:
Michael J. Carvan, Qing Liu, Jan M. Spitsbergen, Tiago S. Hori, Jeremy K. Larson, Reinhold J. Hutz, Giles Goetz, Steven Geis, Matthew L. Rise, Joseph McGraw, Mark Mieritz
Publikováno v:
Aquatic Toxicology. :356-368
The goal of this project was to use functional genomic methods to identify molecular biomarkers as indicators of the impact of TCDD exposure in rainbow trout. Specifically, we investigated the effects of chronic dietary TCDD exposure on whole juvenil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8829264912bf58848b734734acae4166
https://doi.org/10.1016/j.aquatox.2013.06.018
https://doi.org/10.1016/j.aquatox.2013.06.018
Autor:
Kathleen Harper, Richard C. Hubbard, G. Steven Geis, Carl‐Bertil Wallemark, Margaret E. Slater, Aziz Karim, Antoni Piergies, Dwain S. Tolbert
Publikováno v:
The Journal of Clinical Pharmacology. 40:655-663
The objective of this study was to determine the effects of celecoxib, an anti-inflammatory/analgesic agent that primarily inhibits COX-2 and not COX-1 at therapeutic doses, on the steady-state pharmacokinetic profile and hypoprothrombinemic effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baf8e6f9838073bf594b80ce7b92462
https://doi.org/10.1002/j.1552-4604.2000.tb05992.x
https://doi.org/10.1002/j.1552-4604.2000.tb05992.x
Autor:
Aziz Karim, Richard C. Hubbard, G. Steven Geis, Peter C. Isakson, Shawn S. Yu, Philip T. Leese
Publikováno v:
The Journal of Clinical Pharmacology. 40:124-132
Conventional nonsteroidal anti-inflammatory drugs (NSAIDs) nonspecifically inhibit cyclooxygenase-1 (COX-1), an enzyme critical to normal platelet function, and COX-2, which mediates inflammatory response mechanisms. Celecoxib, an antiarthritic agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302275388d225c8338061d079d2053b2
https://doi.org/10.1177/00912700022008766
https://doi.org/10.1177/00912700022008766
Autor:
Peter C. Isakson, Helen Stead, Mario Guslandi, Kenneth M. Verburg, Raphael Naudin, Tore K Kvien, Richard C. Hubbard, G. Steven Geis, Paul Emery, Henning Zeidler
Publikováno v:
The Lancet. 354:2106-2111
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclo-oxygenase (COX), which leads to suppression of COX-1-mediated production of gastrointestinal-protective prostaglandins. Gastrointestinal injury is a common outcome. We compared the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e2e28a1a527c1c88da43b50514ba1
https://doi.org/10.1016/s0140-6736(99)02332-6
https://doi.org/10.1016/s0140-6736(99)02332-6
Autor:
G. Steven Geis, Robert D. Wurster
Publikováno v:
Journal of Cardiovascular Electrophysiology. 2:s26-s33
Spinal Pathways for Somatocardiac Reflexes. Small, somatic afferent fibers, among which mediate painful responses, have important influences on the functions of the heart and vasculature by reflexly controlling autonomic nervous system activity. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14473090a4b6e4865ede503afd98e5e0
https://doi.org/10.1111/j.1540-8167.1991.tb01365.x
https://doi.org/10.1111/j.1540-8167.1991.tb01365.x
Autor:
James B. Lefkowith, G. Steven Geis, Roland W. Moskowitz, William W. Zhao, Andrew M. Brugger, Abraham Sunshine
Publikováno v:
American journal of therapeutics. 10(1)
The aim of this study was to evaluate the utility of the American Pain Society (APS) questionnaire in the assessment of osteoarthritis (OA) pain and to determine the onset of action of celecoxib in the treatment of acute flare pain in patients with O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562e3e99e6d55a5fd52c432ff837a27e
https://pubmed.ncbi.nlm.nih.gov/12522515
https://pubmed.ncbi.nlm.nih.gov/12522515
Autor:
James B. Lefkowith, William B. White, Clement Maurath, Nancy J Ridge, Andrew Whelton, Gerald A. Faich, G. Steven Geis, Kenneth M. Verburg
Publikováno v:
The American journal of cardiology. 89(4)
It has been hypothesized that cyclooxygenase 2 specific inhibitors may increase the risk of cardiovascular (CV) thromboembolic events because of their inhibition of vascular prostacyclin synthesis and lack of an effect on platelet thromboxane A(2) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8e574da8dde25f5ff1b381b8dbeb83
https://pubmed.ncbi.nlm.nih.gov/11835924
https://pubmed.ncbi.nlm.nih.gov/11835924
Publikováno v:
Clinical therapeutics. 23(2)
Current outpatient management of postoperative pain includes the use of oral opioid analgesics or nonsteroidal anti-inflammatory drugs; however, both types of medications are associated with side effects that can limit their usefulness in the outpati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbeda6d30c47ba0f8b06fb6f1a136c0
https://pubmed.ncbi.nlm.nih.gov/11293556
https://pubmed.ncbi.nlm.nih.gov/11293556