Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Steven G. Irving"'
Publikováno v:
Blood. 96:2841-2848
The malignant Reed-Sternberg cell of Hodgkin disease is an aberrant B cell that persists in an immunolgically mediated inflammatory infiltrate. Despite its nonproductive immunoglobulin genes, the Reed-Sternberg cell avoids the usual apoptotic fate of
Autor:
Steven G. Irving, M. Hunter Jamerson, Rita M. Braziel, Christina Messineo, Eileen Hunter, Jeffrey Cossman, Adam Bagg
Publikováno v:
Blood. 91:2443-2451
Although Hodgkin's disease is highly responsive to treatments that cause apoptosis, it remains resistant to the physiological mechanisms intended to cause cell death. Presumably, the Reed-Sternberg cell defies endogenous apoptosis, persists, accumula
Autor:
Cyrus V. Hedvat, Steven G. Irving
Publikováno v:
Molecular Endocrinology. 9:1692-1700
The nuclear (steroid/thyroid/retinoid) receptor superfamily is a set of evolutionarily related ligand-inducible regulators of transcription. One subgroup within this family has been termed the orphan receptors because the potential ligands required f
Publikováno v:
Cytokine. 5:112-116
The expression and regulation of seven human members of a family of related cytokines, which play a role as effectors of inflammation, were analysed in hemopoietic cells and in fibroblasts. In T lymphocytes all genes: platelet basic protein (PBP); pl
Publikováno v:
Biochemical and biophysical research communications. 231(1)
We previously identified a DNA binding element termed the upstream regulatory element (URE) that contains the consensus initiator sequence (Inr) in the upstream promoter of the rat prodynorphin gene. The URE displays specific binding to the upstream
Autor:
Steven G. Irving, Saori Kamesaki, Ginette Y. Michaud, Kamesaki H, Jeffrey Cossman, Minoru Okuma, Naruyoshi Suwabe
Publikováno v:
Blood. 87(3)
GATA-1 protein is thought to be a positive regulator of erythroid differentiation. However, ectopic expression of a conditional GATA- 2/estrogen receptor chimera was shown to inhibit erythroid differentiation in a hormone-dependent manner, suggesting
Autor:
Douglas R. Oliveri, Hamid Siragy, Ginette Y. Michaud, Nicholas Sioutos, Adam Bagg, Steven G. Irving, Jeffrey Cossman, Joseph Locker, Dan P. Hartmann
Publikováno v:
Diagnostic molecular pathology : the American journal of surgical pathology, part B. 4(1)
To determine efficiently the clonality of B-cell lymphoproliferative disorders, we modified an immunoglobulin heavy-chain (IGH) gene rearrangement polymerase chain reaction (PCR) assay that requires only a single primer germline variable (VH) and joi
Publikováno v:
Arthroscopy : the journal of arthroscopicrelated surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 10(6)
Summary Meniscal replacement by allograft and meniscal regeneration through collagen meniscal scaffolds have been recently reported. To evaluate the effectiveness of a replaced or regrown meniscal cartilage, a method for measuring the size and functi
Publikováno v:
British Veterinary Journal. 141:129-134
Adult ewes were given 1·5 g cyclophosphamide intravenously, and 68 days later received an intrapulmonary inoculation of virus preparations isolated from a sheep bronchoalveolar carcinoma. The animals were under continuous inspection for a year after
Publikováno v:
Virology. 124:192-195
The genetic relatedness among viral genomes of caprine arthritis-encephalitis virus, visna virus, and progressive pneumonia virus, was determined. Whereas the genomic RNAs of two strains of visna virus are indistinguishable as reflected both by their