Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Steven G Williams"'
Autor:
Rebecca C. Poulos, Peter G. Hains, Rohan Shah, Natasha Lucas, Dylan Xavier, Srikanth S. Manda, Asim Anees, Jennifer M. S. Koh, Sadia Mahboob, Max Wittman, Steven G. Williams, Erin K. Sykes, Michael Hecker, Michael Dausmann, Merridee A. Wouters, Keith Ashman, Jean Yang, Peter J. Wild, Anna deFazio, Rosemary L. Balleine, Brett Tully, Ruedi Aebersold, Terence P. Speed, Yansheng Liu, Roger R. Reddel, Phillip J. Robinson, Qing Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Clinical proteomics critically depends on the ability to acquire highly reproducible data over an extended period of time. Here, the authors assess reproducibility over four months across different mass spectrometers and develop a computational appro
Externí odkaz:
https://doaj.org/article/f31d48fe5cbd4e4fb32261099a109959
Autor:
Luminita Gabriela Horga, Samantha Halliwell, Tania Selas Castiñeiras, Chris Wyre, Cristina F. R. O. Matos, Daniela S. Yovcheva, Ross Kent, Rosa Morra, Steven G. Williams, Daniel C. Smith, Neil Dixon
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-18 (2018)
Abstract Background The secretion of recombinant disulfide-bond containing proteins into the periplasm of Gram-negative bacterial hosts, such as E. coli, has many advantages that can facilitate product isolation, quality and activity. However, the se
Externí odkaz:
https://doaj.org/article/567a76b5935f40208a61c4b153a36b6e
Autor:
Tania Selas Castiñeiras, Steven G. Williams, Antony Hitchcock, Jeffrey A. Cole, Daniel C. Smith, Tim W. Overton
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract Targeting of recombinant proteins to the Escherichia coli periplasm is a desirable industrial processing tool to allow formation of disulphide bonds, aid folding and simplify recovery. Proteins are targeted across the inner membrane to the p
Externí odkaz:
https://doaj.org/article/dd6e1f24aab44fdcaedaf5ac20461022
Autor:
Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J Seneviratne, Erin Sykes, Frances Thomas, Sara Valentini, Steven G Williams, Yangxiu Wu, Dylan Xavier, Karen L MacKenzie, Peter G Hains, Brett Tully, Phillip J Robinson, Qing Zhong, Mathew J Garnett, Roger R Reddel
SummaryThe proteome provides unique insights into biology and disease beyond the genome and transcriptome. Lack of large proteomic datasets has restricted identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab6090375c95783a1345c281a33a98b
https://doi.org/10.1101/2022.02.26.482008
https://doi.org/10.1101/2022.02.26.482008
Publikováno v:
Techniques and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d898532491296ac6eca9598d24b9e3
https://doi.org/10.3133/tm2a19
https://doi.org/10.3133/tm2a19
Autor:
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yangxiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip J. Robinson, Qing Zhong, Mathew J. Garnett, Roger R. Reddel
Publikováno v:
Cancer Cell
The proteome provides unique insights into disease biology beyond the genome and transcriptome. A lack of large proteomic datasets has restricted the identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3a20c7e98090d73382989efa0e217c
https://pubmed.ncbi.nlm.nih.gov/35839778
https://pubmed.ncbi.nlm.nih.gov/35839778
Autor:
Leah Dunn, Mackenzie Case, Kevin J. Gergely, Steven G. Williams, Anne Davidson, Alexa J. McKerrow
Publikováno v:
Global Ecology and Conservation, Vol 28, Iss, Pp e01598-(2021)
Preserving biodiversity and its many components is a priority of conservation science and how to efficiently allocate resources to preserve healthy populations of as many species, habitats, and ecosystems as possible. We used the U.S. Geological Surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e753bea73ef48204343876c766a25c
http://www.sciencedirect.com/science/article/pii/S2351989421001487
http://www.sciencedirect.com/science/article/pii/S2351989421001487
Autor:
Keith Ashman, Asim Anees, Terence P. Speed, Erin K. Sykes, Roger R. Reddel, Yansheng Liu, Jennifer M. S. Koh, Jean Yang, Merridee A. Wouters, Steven G. Williams, Peter J. Wild, Anna deFazio, Natasha Lucas, Max Wittman, Dylan Xavier, Michael Hecker, Sadia Mahboob, Michael Dausmann, Ruedi Aebersold, Peter G. Hains, Brett Tully, Rohan Shah, Phillip J. Robinson, Qing Zhong, Rosemary L. Balleine, Srikanth S. Manda, Rebecca C. Poulos
Publikováno v:
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72057dd71a63badf92c2a0858853f64
https://hdl.handle.net/20.500.11850/430457
https://hdl.handle.net/20.500.11850/430457
Publikováno v:
Journal of Fish and Wildlife Management. 9:554-564
Effective habitat conservation is predicated on maintaining high levels or increasing local persistence probability of the species it purports to protect. Thus, methodological approaches that improve the inferential value of local persistence are of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75cad17a840743f5a4a68069860320d6
https://doi.org/10.3996/112017-jfwm-089
https://doi.org/10.3996/112017-jfwm-089
Publikováno v:
Diversity and Distributions. 24:1464-1477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc2365896d300bb168bfa578d5357f5
https://doi.org/10.1111/ddi.12779
https://doi.org/10.1111/ddi.12779